29 research outputs found

    Psychological adjustment and heart rate variability in ovarian cancer survivors

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    Introduction: Body image, posttraumatic growth, quality of life, coping, and social support are relevant concepts to ovarian cancer survivors. This study aimed to examine the associations among these concepts as well as their relationships with heart rate variability (HRV), which is an index of vagal tone. Methods: an exploratory and correlational study was conducted on 25 ovarian cancer survivors. We used self-report measures to assess psychological variables. HRV parameters recorded for this study were analyzed in the time domain and in the frequency domain. Spearman correlations were performed. Results: Positive attitude coping strategy was associated with psychological and physical distress related to problems of appearance (Rho = -.57, p < .01), emotional functioning (Rho = .53, p < .01), and global health (Rho = .47, p < .05). Problem solving coping strategy was correlated with a higher posttraumatic growth, namely greater personal strength (Rho = .44, p < .05) and better relationships with others (Rho = .40, p < .05). Seeking social support was associated with growth in relationships with others (Rho = .40, p < .05). Higher HRV parameters were associated with higher physical functioning (SDNN: Rho = .59, p < .01; RMSSD: Rho = .54; p < .01; pNN50: Rho = .56, p < .01; HF: Rho = .58, p < .01). The ratio of low-frequency to high-frequency power (LF/HF) was negatively associated with posttraumatic growth (i.e., personal strength: Rho = .51, p < .05; new possibilities: Rho = -.54, p < .01). Discussion: Positive attitude and problem solving coping strategies may facilitate psychological adjustment to ovarian cancer. The strong association between markers of vagal tone and physical functioning offers insights on the possible role of vagus nerve in ovarian cancer survivors. These findings should be further investigated by future studies with larger samples and longitudinal designs

    JWSTJWST Insight Into a Lensed HSTHST-dark Galaxy and its Quiescent Companion at z=2.58z=2.58

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    Using the novel JWSTJWST/NIRCam observations in the Abell 2744 field, we present a first spatially resolved overview of an HSTHST-dark galaxy, spectroscopically confirmed at z=2.58z=2.58 with magnification μ≈1.9\mu\approx1.9. While being largely invisible at ∼\sim1 μ\mum with NIRCam, except for sparse clumpy sub-structures, the object is well-detected and resolved in the long-wavelength bands with a spiral shape clearly visible in F277W. By combining ancillary ALMA and HerschelHerschel data, we infer that this object is an edge-on dusty spiral with an intrinsic stellar mass log(M∗/M⊙)∼11.3(M_*/M_\odot)\sim11.3 and a dust-obscured SFR∼300 M⊙\sim 300~M_\odot~yr−1^{-1}. A massive quiescent galaxy (log(M∗/M⊙)∼10.8(M_*/M_\odot)\sim10.8) with tidal features lies 2\farcs{0} away (rr∼\sim9 kpc), at a consistent redshift as inferred by JWSTJWST photometry, indicating a potential major merger. The dusty spiral lies on the main-sequence of star formation, and shows high dust attenuation in the optical (3<AV<4.53<A_{\rm V}<4.5). In the far-infrared, its integrated dust SED is optically thick up to λ0∼500\lambda_0 \sim 500 μ\mum, further supporting the extremely dusty nature. Spatially resolved analysis of the HSTHST-dark galaxy reveals a largely uniform AV∼4A_{\rm V}\sim 4 area spanning ∼\sim57 kpc2^2, which spatially matches to the ALMA 1 mm continuum emission. Accounting for the surface brightness dimming and the depths of current JWSTJWST surveys, unlensed analogs of the HSTHST-dark galaxy at z>4z>4 would be only detectable in F356W and F444W in UNCOVER-like survey, and become totally JWSTJWST-dark at z∼6z\sim6. This suggests that detecting highly attenuated galaxies in the Epoch of Reionization might be a challenging task for JWSTJWST.Comment: 15 pages, 5 figures, 1 table. Accepted to ApJ