Predicting Flux And Pressure Relationships of Large Scale Filtration with USD Model Inputs: Method and application

Ultra Scale-Down tools have demonstrated the huge benefit for rapid process development with reduced material requirement and better solutions. In this poster, a method was reported to predict the flux and transmembrane pressure relationships of a diafiltration application for a crossflow filtration (CFF) process, based on data generated using an Ultra Scale-Down (USD) device that uses dead-end mode of operation to mimic CFF. A new flux prediction protocol was developed to accurately determine the system resistance of large scale crossflow filtration (CFF) systems, and, to predict CFF performance using USD data. Antibody fragment (Fab’) is expressed in E. coli as an intracellular product and E.coli homogenate was used for scale-up studies and to validate the prediction results. Predicted and actual flux-pressure drop and transmission data showed good agreement. Wall shear rate correlations have been established for both the lab scale cassette and the USD device, and a mimic has been developed by operating both scales at equivalent membrane averaged shear rates

A new approach in chaos shift keying for secure communication

A chaotic sequence for chaos shift keying (CSK) that provides auto- and cross-correlation properties (that are similar to those of random white noise) is used for spread spectrum systems. Due to its bifurcation behavior (depending on the initial condition), the number of chaotic sequences that can be generated by a single formula is not restricted and will not repeat itself. These characteristics provide an increase in system capacity and security performance. The paper presents a study of two different commonly used chaotic logistic maps and a modified chaotic logistic map for CSK spread spectrum system. The newly modified logistic map provides similar bits error rate (BER) performance to the best logistic map. Yet, it also provides an additional chaotic parameter for the control of its dynamic property, hence increasing the system security and capacity

There are no abnormal solutions of the Bethe−-Salpeter equation in the static model

The four-point Green's function of static QED, where a fermion and an antifermion are located at fixed space positions, is calculated in covariant gauges. The bound state spectrum does not display any abnormal state corresponding to excitations of the relative time. The equation that was established by Mugibayashi in this model and which has abnormal solutions does not coincide with the Bethe$-$Salpeter equation. Gauge transformation from the Coulomb gauge also confirms the absence of abnormal solutions in the Bethe$-$Salpeter equation.Comment: 11 pages, late

Variations in bilingual processing of positive and negative information

Past research suggests that the emotional content of words has greater impact when presented in a bilingual's first language (L1) compared to their second language (L2). This is predicted to be a consequence of automatic processing of emotional words in L1 compared to slower, semantic processing in L2. In the current study 58 Chinese-English bilinguals from Hong Kong rated the valence and arousal of positive, neutral, and negative words presented in Chinese (L1) and English (L2). In contrast to predictions, perceived emotionality of the words was higher in L2, with positive words rated more positively and negative words rated more negatively when presented in English compared to Chinese. The findings suggest that words presented in L2 did not have lower emotional impact than L1, the results indicate that emotional processing of words may be influenced by language proficiency and language complexity

Capital Flows Management During the Post-2007 Global Financial Crisis: The Experiences of SEACEN Economies

Although global financial stability in late 2010 and early 2011 has, in general, improved when compared to the 2008-2009 period of the sub-prime global financial crisis, vulnerabilities remain high. The recent World Economic Outlook of the IMF (WEO, September 2011) underlines the two speed recovery processes taking place in the world economies. In advanced economies, especially those hit hardest by the crisis, firms, government and household sectors continue to be heavily indebted and are likely to spur relatively weak demand. Although the financial markets of these economies have, in most parts, returned to profitability, the overall frail balance sheets reflect the general subdued state of the local economy. In sharp contrast, the emerging economies, including those of the SEACEN region, are posting robust growth rates until the second half of 2011, meeting new challenges associated with strong demand, rapid credit and excess liquidity. Price pressures, including potential asset price bubbles, have been the common themes of policy challenges for the SEACEN economies. Managing macro-financial risks, namely balancing growth, balance sheet soundness of the financial institutions, particularly the banking sector, and keeping a lid on inflationary pressures, have been and will likely be the primary policy challenges for these emerging markets in 2011 and 2012. This paper takes stock of recent trends and developments with regard to capital flows in the SEACEN economies. It elaborates in detail, the breakdowns and compositions of the flows. In particular, the focus of the analyses is on key flows such as the international bank lending activities to the region. The paper also summarises and analyses some of the basic push and pull factors of these flows to understand some of the domestic and external drivers of these flows. Some of the economic consequences of these capital flows and policy dilemma facing the SEACEN economies are also looked at. The paper also examines the policy responses of the central banks/monetary authorities, in particular, to mitigate the negative consequences and maximise the benefits of capital flows.

Interrater reliability in visual identification of interictal high-frequency oscillations on electrocorticography and scalp EEG.

High-frequency oscillations (HFOs), including ripples (Rs) and fast ripples (FRs), are promising biomarkers of epileptogenesis, but their clinical utility is limited by the lack of a standardized approach to identification. We set out to determine whether electroencephalographers experienced in HFO analysis can reliably identify and quantify interictal HFOs. Two blinded raters independently reviewed 10 intraoperative electrocorticography (ECoG) samples from epilepsy surgery cases, and 10 scalp EEG samples from epilepsy monitoring unit evaluations. HFOs were visually marked using bandpass filters (R, 80-250 Hz; FR, 250-500 Hz) with a sampling frequency of 2,000 Hz. There was agreement as to the presence or absence of epileptiform discharges (EDs), Rs, and FRs, in 17, 18, and 18 cases, respectively. Interrater reliability (IRR) was favorable with κ = 0.70, 0.80, and 0.80, respectively, and similar for ECoG and scalp electroencephalography (EEG). Furthermore, interclass correlation for rates of Rs (0.99, 95% confidence interval [CI] 0.96-0.99) and FRs (0.77, 95% CI 0.41-0.91) were superior in comparison to EDs (0.37, 95% CI -0.60 to 0.75). Our data suggest that HFO identification and quantification are reliable among experienced electroencephalographers. Our findings support the reliability of utilizing HFO data in both research and clinical arenas

A Physico-Chemical study of different Fig (Ficus Carica L.) varieties in Haramosh valley, Gilgit-Pakistan

The present study was conducted to analysis the basic physico-chemical properties of four Figs (Ficus carica L.) varieties i.e. English Fig, wild fig, dark brown fig and dark black fig and its by-products was prepared in Haramosh valley.Fresh fig fruits were picked or harvested when they begin to soften and the color change indicates maturity. Then washed, cut in quarters, pulped and then the pulp was processed into fig jam and squash. The physico-chemical analysis i.e. pH, total soluble solids (TSS), titratable acidity, reducing sugar, moisture content and ash content of four fresh varieties of fig were determined while physico-chemical analysisof by-products (Jam and squash) prepared from three fig varieties including english, dark brown and dark black fig was also determined. The results showed that pH and moisture content were gradually decreased in all samples during storage interval whereas TSS, titratable acidity, reducing sugar and ash content increased. Regarding physico-chemical analysis of by-products TSS, acidity, reducing sugar, non-reducing sugar and total sugar increased while pH decreased during storage interval.The maximum mean value for pH, moisture content and ash content was found in English fig however for TSS and reducing sugar maximum value was observed in dark black fig. Data regarding titratable acidity highest value was recorded from wild fig. Furthermore pysico-chemical properties of by-products shows that maximum mean value of pH was detected in dark brown fig whereas maximum value of acidity, TSS, reducing sugar and total sugar was recorded from English fig, however maximum value of non-reducing sugar was observed in dark black fig. It may be concluded from the study that English fig is favorable for a long period of storage.Moreover it is concluded that processing of fig fruit pulp into jam and squash resulted in a significant increase in physico-chemical characteristics such as TSS, titratable acidiy and sugar content however decreases its pH. The processing of fig fruit pulp into jam and squash ensures the safety and quality of the by-products without losing its nutritional and antioxidant benefits

Complex magnetic topology and strong differential rotation on the low-mass T Tauri star V2247 Oph

From observations collected with the ESPaDOnS spectropolarimeter at the Canada-France-Hawaii Telescope, we report the detection of Zeeman signatures on the low-mass classical TTauri star (cTTS) V2247Oph. Profile distortions and circular polarisation signatures detected in photospheric lines can be interpreted as caused by cool spots and magnetic regions at the surface of the star. The large-scale field is of moderate strength and highly complex; moreover, both the spot distribution and the magnetic field show significant variability on a timescale of only one week, as a likely result of strong differential rotation. Both properties make V2247Oph very different from the (more massive) prototypical cTTS BPTau; we speculate that this difference reflects the lower mass of V2247Oph. During our observations, V2247Oph was in a low-accretion state, with emission lines showing only weak levels of circular polarisation; we nevertheless find that excess emission apparently concentrates in a mid-latitude region of strong radial field, suggesting that it is the footpoint of an accretion funnel. The weaker and more complex field that we report on V2247Oph may share similarities with those of very-low-mass late-M dwarfs and potentially explain why low-mass cTTSs rotate on average faster than intermediate mass ones. These surprising results need confirmation from new independent data sets on V2247Oph and other similar low-mass cTTSs.Comment: MNRAS (in press) - 12 pages, 9 figure

Electronic superlattice revealed by resonant scattering from random impurities in Sr3Ru2O7

Resonant elastic x-ray scattering (REXS) is an exquisite element-sensitive tool for the study of subtle charge, orbital, and spin superlattice orders driven by the valence electrons, which therefore escape detection in conventional x-ray diffraction (XRD). Although the power of REXS has been demonstrated by numerous studies of complex oxides performed in the soft x-ray regime, the cross section and photon wavelength of the material-specific elemental absorption edges ultimately set the limit to the smallest superlattice amplitude and periodicity one can probe. Here we show -- with simulations and REXS on Mn-substituted Sr$_3$Ru$_2$O$_7$ -- that these limitations can be overcome by performing resonant scattering experiments at the absorption edge of a suitably-chosen, dilute impurity. This establishes that -- in analogy with impurity-based methods used in electron-spin-resonance, nuclear-magnetic resonance, and M\"ossbauer spectroscopy -- randomly distributed impurities can serve as a non-invasive, but now momentum-dependent probe, greatly extending the applicability of resonant x-ray scattering techniques