Table1_A multi-branch network to detect post-operative complications following hip arthroplasty on X-ray images.pdf

Background: Postoperative complications following total hip arthroplasty (THA) often require revision surgery. X-rays are usually used to detect such complications, but manually identifying the location of the problem and making an accurate assessment can be subjective and time-consuming. Therefore, in this study, we propose a multi-branch network to automatically detect postoperative complications on X-ray images.Methods: We developed a multi-branch network using ResNet as the backbone and two additional branches with a global feature stream and a channel feature stream for extracting features of interest. Additionally, inspired by our domain knowledge, we designed a multi-coefficient class-specific residual attention block to learn the correlations between different complications to improve the performance of the system.Results: Our proposed method achieved state-of-the-art (SOTA) performance in detecting multiple complications, with mean average precision (mAP) and F1 scores of 0.346 and 0.429, respectively. The network also showed excellent performance at identifying aseptic loosening, with recall and precision rates of 0.929 and 0.897, respectively. Ablation experiments were conducted on detecting multiple complications and single complications, as well as internal and external datasets, demonstrating the effectiveness of our proposed modules.Conclusion: Our deep learning method provides an accurate end-to-end solution for detecting postoperative complications following THA.</p

Data from previous studies examining risk factors for periprosthetic joint infection (PJI) or surgical site infection (SSI) in patients who underwent THA and TKA.

<p>Abbreviations: THA, total hip arthroplasty; TKA, total knee arthroplasty; TJA, total joint arthroplasty.</p

Risk Factors for Periprosthetic Joint Infection after Total Hip Arthroplasty and Total Knee Arthroplasty in Chinese Patients

<div><p>Purpose</p><p>The purpose of this hospital-based case–control study was to evaluate the risk factors for periprosthetic joint infection (PJI) of total hip arthroplasty (THA) and total knee arthroplasty (TKA) in Chinese patients.</p><p>Method</p><p>From January 2000 to December 2012, 45 patients undergoing THA and TKA who developed PJI were recruited for case subjects; controls were 252 without PJI, matched by year of index for surgery and type of surgery. Conditional logistic regressions were run to compute odds ratios (ORs) and 95% confidence intervals (CIs).</p><p>Results</p><p>Demographic factors and comorbid conditions associated with an increased adjusted risk of PJI (in decreasing order of significance) were diabetes (OR = 5.47, 95% CI: 1.77–16.97; <i>p</i> = 0.003), age (65–75 vs. 45–65 years) (OR = 3.36, 95% CI: 1.30–8.69; <i>p</i> = 0.013), BMI (≥28 vs. 18.5–28 kg/m²) (OR = 2.77, 95% CI: 1.20–6.40; <i>p</i> = 0.017), place of residence (rural) (OR = 2.63, 95% CI: 1.13–6.10; <i>p</i> = 0.025) and alcohol abuse (OR = 2.95, 95% CI: 1.06–8.23; <i>p</i> = 0.039).</p><p>Conclusion</p><p>Patients with diabetes, older age, BMI of ≥28 kg/m² and alcohol abuse or living in rural areas, had increased PJI risk. Additional systematic large-scale studies are needed to verify these results.</p></div

Patient demographics and other characteristics according to aseptic loosening status.

<p>: X² test for the variables; THA: total hip arthroplasty; TKA: total knee arthroplasty.</p

Patient comorbidities according to occurrence of PJI.

<p>All values are expressed as n (%).</p><p>*According to the chi-square test.</p

Cytoprotective Genes Identified by Functional Cloning.

<p>Cytoprotective Genes Identified by Functional Cloning.</p

Calmodulin overexpression protects against OGD and NMDA Excitotoxicity.

<p>(A and B) Representative photomicrographs of cortical cultures transfected with empty vector or calmodulin and then exposed to (A) 90 min OGD or (B) 500 µM NMDA for 5 min. Cell death was assessed 24 h later. Arrows or arrowheads indicate dead or surviving transfected neurons, respectively.</p

Independent risk factors for PJI after multivariate regression analysis.

<p>Abbreviations: BMI, body mass index; CI, confidence interval; THA, total hip arthroplasty; TKA, total knee arthroplasty.</p

Data from previous studies examining risk factors (positive results in this article) for periprosthetic joint infection or surgical site infection in patients who underwent THA and TKA, in detail.

<p>Abbreviations: BMI, body mass index; HR, hazard ratio; NS, not significant; OA, osteoarthritis; OR, odds ratio; THA, total hip arthroplasty; TKA, total knee arthroplasty; RR, relative risk.</p

Patient comorbid conditions according to aseptic loosening status.

<p>: X² test for the variables; BMI: body mass index.</p