5,283 research outputs found
Universal Ratios of Characteristic Lengths in Semidilute Polymer Solutions
We use experimental and simulation data from the literature to infer five
characteristic lengths, denoted , , , , and
of a semidilute polymer solution. The first two of these are defined in
terms of scattering from the solution, the third is defined in terms of osmotic
pressure, the fourth by the spatial monomer concentration profile, and the last
by co-operative diffusion. In a given solution the ratios of any of these five
lengths are expected to be universal constants. Knowing these constants thus
allows one to use one measured property of a solution as a means of inferring
others. We calculate these ratios and estimate their uncertainties for
solutions in theta as well as good-solvent conditions. The analysis is
strengthened by use of scattering properties of isolated polymers inferred from
computer simulations.Comment: 15 pages(pdf), to be submitted to Macromolecules or J. Chem. Phy
Confined Multilamellae Prefer Cylindrical Morphology
By evaporating a drop of lipid dispersion we generate the myelin morphology
often seen in dissolving surfactant powders. We explain these puzzling
nonequilibrium structures using a geometric argument: The bilayer repeat
spacing increases and thus the repulsion between bilayers decreases when a
multilamellar disk is converted into a myelin without gain or loss of material
and with number of bilayers unchanged. Sufficient reduction in bilayer
repulsion can compensate for the cost in curvature energy, leading to a net
stability of the myelin structure. A numerical estimate predicts the degree of
dehydration required to favor myelin structures over flat lamellae.Comment: 6 pages, 3 figures, submitted to Euro. Phys. J.
Explore the Functional Connectivity between Brain Regions during a Chemistry Working Memory Task.
Previous studies have rarely examined how temporal dynamic patterns, event-related coherence, and phase-locking are related to each other. This study assessed reaction-time-sorted spectral perturbation and event-related spectral perturbation in order to examine the temporal dynamic patterns in the frontal midline (F), central parietal (CP), and occipital (O) regions during a chemistry working memory task at theta, alpha, and beta frequencies. Furthermore, the functional connectivity between F-CP, CP-O, and F-O were assessed by component event-related coherence (ERCoh) and component phase-locking (PL) at different frequency bands. In addition, this study examined whether the temporal dynamic patterns are consistent with the functional connectivity patterns across different frequencies and time courses. Component ERCoh/PL measured the interactions between different independent components decomposed from the scalp EEG, mixtures of time courses of activities arising from different brain, and artifactual sources. The results indicate that the O and CP regions' temporal dynamic patterns are similar to each other. Furthermore, pronounced component ERCoh/PL patterns were found to exist between the O and CP regions across each stimulus and probe presentation, in both theta and alpha frequencies. The consistent theta component ERCoh/PL between the F and O regions was found at the first stimulus and after probe presentation. These findings demonstrate that temporal dynamic patterns at different regions are in accordance with the functional connectivity patterns. Such coordinated and robust EEG temporal dynamics and component ERCoh/PL patterns suggest that these brain regions' neurons work together both to induce similar event-related spectral perturbation and to synchronize or desynchronize simultaneously in order to swiftly accomplish a particular goal. The possible mechanisms for such distinct component phase-locking and coherence patterns were also further discussed
Structural insights into the gating of DNA passage by the topoisomerase II DNA-gate.
Type IIA topoisomerases (Top2s) manipulate the handedness of DNA crossovers by introducing a transient and protein-linked double-strand break in one DNA duplex, termed the DNA-gate, whose opening allows another DNA segment to be transported through to change the DNA topology. Despite the central importance of this gate-opening event to Top2 function, the DNA-gate in all reported structures of Top2-DNA complexes is in the closed state. Here we present the crystal structure of a human Top2 DNA-gate in an open conformation, which not only reveals structural characteristics of its DNA-conducting path, but also uncovers unexpected yet functionally significant conformational changes associated with gate-opening. This structure further implicates Top2's preference for a left-handed DNA braid and allows the construction of a model representing the initial entry of another DNA duplex into the DNA-gate. Steered molecular dynamics calculations suggests the Top2-catalyzed DNA passage may be achieved by a rocker-switch-type movement of the DNA-gate
Dynamic evaluation of a mini train powered by the hybrid fuel cell
Fuel cell system is widely used in the mobile devices and USA space program. This project studies the feasibility of powering a small train with a hybrid fuel cell system by employing electric power integration technology. Specifically, this study performs the dynamic tests on a mini train powered by Proton Exchange Membrane Fuel Cell (PEMFC). The original 12 V, 100 AH lead-acid battery, which can provide 12 V, 0.5 Hp for the locomotive and carry 9~12 people, is replaced by a hybrid Proton Exchange Membrane Fuel Cell. After an oval railroad and a low-pressure metal hydrogen storage canister recharging station are built, the mini train is tested on weekend and holidays at the outdoor park of National Science and Technology Museum, Taiwan. The dynamic performance of the PEMFC system is analyzed and the feasibility of applying this system to mini trains is evaluated. After one year of running, the mini train has been operated over 1,200 hours and has been transported over 30,000 passengers. The hybrid PEMFC system works perfectly and meets the original goal. Results also indicate that the temperature significantly affects system performance
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Expansion of Thaumarchaeota habitat range is correlated with horizontal transfer of ATPase operons.
Thaumarchaeota are responsible for a significant fraction of ammonia oxidation in the oceans and in soils that range from alkaline to acidic. However, the adaptive mechanisms underpinning their habitat expansion remain poorly understood. Here we show that expansion into acidic soils and the high pressures of the hadopelagic zone of the oceans is tightly linked to the acquisition of a variant of the energy-yielding ATPases via horizontal transfer. Whereas the ATPase genealogy of neutrophilic Thaumarchaeota is congruent with their organismal genealogy inferred from concatenated conserved proteins, a common clade of V-type ATPases unites phylogenetically distinct clades of acidophilic/acid-tolerant and piezophilic/piezotolerant species. A presumptive function of pumping cytoplasmic protons at low pH is consistent with the experimentally observed increased expression of the V-ATPase in an acid-tolerant thaumarchaeote at low pH. Consistently, heterologous expression of the thaumarchaeotal V-ATPase significantly increased the growth rate of E. coli at low pH. Its adaptive significance to growth in ocean trenches may relate to pressure-related changes in membrane structure in which this complex molecular machine must function. Together, our findings reveal that the habitat expansion of Thaumarchaeota is tightly correlated with extensive horizontal transfer of atp operons
A LITERATURE REVIEW OF SUSTAINABLE TOURISM (1990-2016): DEVELOPMENT TRAJECTORY AND FRAMEWORK
Purpose of the study—Tourism is one of the largest and fastest growing industries in the world. Just like an enterprise today, sustainability is the long-term objective pursued by tourism industry. However, little effort has been made to systematically provide sufficient information to academicians and practitioners who have great research interests in sustainable tourism. Therefore, this paper aims to figure out the knowledge mapping of sustainable tourism and to indicate its research hot spots and trends for future research.
Methodology—This paper surveys the development trajectory of sustainable tourism using a literature review and classification of articles retrieved from 5 online databases with solo keyword “sustainable tourism” from 1900 to 2016.
Main findings—Based on the scope of 641 articles, this study reveals that the number of publication on sustainable tourism has significantly increased since 2006. In addition, these articles are scattered across 125 journals and mostly published in 23 academic journals. The majority of targeted countries/regions for sustainable tourism focus on Asia, Europe and America.
Limitation—Restricted to limited knowledge, we make a brief literature survey on sustainable tourism from 1990-2016 to explore how sustainable tourism and its applications have developed in this period.
Originality/value—In fact, sustainable tourism is a belief and an overall concept in every tourism activities. Though this research has done lots, it still has rooms to make more complete. Finally, we present a conceptual framework integrating 13 classifications criteria derived from our analysis with 3247 keywords. Most interestingly, we further present a conceptual framework with a visual effect to operationalize the coverage of sustainable tourism. Based on our analysis, any researcher can easily find the popular and right journal to get into it, if he/she is in need, he/she also can roughly know its applications so far and completely get a whole picture of sustainable tourism quickly
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