5 research outputs found
Ligand-Promoted Rh(III)-Catalyzed Coupling of Aryl C–H Bonds with Arylboron Reagents
RhodiumÂ(III)-catalyzed
C–H arylation of arenes with phenylboronic
acid pinacol esters has been achieved using a readily removable <i>N</i>-pentafluorophenylbenzamide directing group for the first
time. The use of a bidentate phosphine ligand (Binap) significantly
increased the yield of the cross-coupling of C–H bonds with
organoboron reagents
Ligand-Promoted Rh(III)-Catalyzed Coupling of Aryl C–H Bonds with Arylboron Reagents
RhodiumÂ(III)-catalyzed
C–H arylation of arenes with phenylboronic
acid pinacol esters has been achieved using a readily removable <i>N</i>-pentafluorophenylbenzamide directing group for the first
time. The use of a bidentate phosphine ligand (Binap) significantly
increased the yield of the cross-coupling of C–H bonds with
organoboron reagents
Rhodium-Catalyzed Direct <i>Ortho</i> C–H Arylation Using Ketone as Directing Group with Boron Reagent
A general method
for selective <i>ortho</i> C–H
arylation of ketone, with boron reagent enabled by rhodium complexes
with excellent yields, is developed. The transformation is characterized
by the use of air-stable Rh catalyst, high monoarylation selectivity,
and excellent yields of most of the substrates
Rh(III)-Catalyzed <i>meta</i>-C–H Olefination Directed by a Nitrile Template
A range of RhÂ(III)-catalyzed <i>ortho</i>-C–H
functionalizations have been developed; however, extension of this
reactivity to remote C–H functionalizations through large-ring
rhodacyclic intermediates has yet to be demonstrated. Herein we report
the first example of the use of a U-shaped nitrile template to direct
RhÂ(III)-catalyzed remote <i>meta</i>-C–H activation
via a postulated 12-membered macrocyclic intermediate. Because the
ligands used for RhÂ(III) catalysts are significantly different from
those of PdÂ(II) catalysts, this offers new opportunities for future
development of ligand-promoted <i>meta</i>-C–H activation
reactions
One-Pot Construction of Heteroarylation/Esterification Products of Acrylic Acids via Iridium(III)-Catalyzed C–H Activation
A carboxylate-assisted iridium(III)-catalyzed regioselective
C(sp2)–H heteroarylation/esterification reaction
of acrylic
acid is disclosed herein for the first time. This catalytic protocol
tolerates various α-substituted, β-substituted, and α,
β-disubstituted acrylic acids as well as heteroaromatic boronates
well. The resulting 3,4-dihydro-2H-pyran-6-carboxylic
acid derivative 3r highlighted the AIE-active luminophore
with multiple emission signal properties and a high quantum yield
of 28%, exhibiting the potential application of this methodology for
the synthesis of nitrogen-containing organic functional materials