A new model based on adiabatic flame temperature for evaluation of the upper flammable limit of alkane-air-CO2 mixtures

© 2017 Elsevier B.V. For security issue of alkane used in Organic Rankine Cycle, a new model to evaluate the upper flammability limits for mixtures of alkanes, carbon dioxide and air has been proposed in present study. The linear relationship was found at upper flammability limits between molar fraction of diluent in alkane-CO 2 mixture and calculated adiabatic flame temperature. The prediction ability of the variable calculated adiabatic flame temperature model that incorporated the linear relationship above is greatly better than the models that adopted the fixed calculated adiabatic flame temperature at upper flammability limit. The average relative differences between results predicted by the new model and observed values are less than 3.51% for upper flammability limit evaluation. In order to enhance persuasion of the new model, the observed values of n-butane-CO 2 and isopentane-CO 2 mixtures measured in this study were used to confirm the validity of the new model. The predicted results indicated that the new model possesses the capacity of practical application and can adequately provide safe non-flammable ranges for alkanes diluted with carbon dioxide

sj-docx-1-inq-10.1177_00469580231217982 – Supplemental material for Associations Among Online Health Information Seeking Behaviors, Electronic Health Literacy and Food Neophobia: A Cross-Sectional Study

Supplemental material, sj-docx-1-inq-10.1177_00469580231217982 for Associations Among Online Health Information Seeking Behaviors, Electronic Health Literacy and Food Neophobia: A Cross-Sectional Study by Hua Tian and Jie Chen in INQUIRY: The Journal of Health Care Organization, Provision, and Financing</p

Enantioselective 6-<i>exo</i>-Bromoaminocyclization of Homoallylic <i>N</i>‑Tosylcarbamates Catalyzed by a Novel Monophosphine-Sc(OTf)₃ Complex

A highly enantioselective 6-<i>exo</i>-bromoaminocyclization of (<i>E</i>)-homoallylic <i>N</i>-tosylcarbamates catalyzed by a novel monophosphine-Sc­(OTf)₃ complex is described, giving a wide variety of optically active oxazinanones with high enantioselectivities

DataSheet_1_The Efficacy of Denosumab in Patients With Rheumatoid Arthritis: A Systematic Review and Pooled Analysis of Randomized or Matched Data.docx

ObjectiveThe purpose of this study was to evaluate the efficacy of denosumab treatment in patients with rheumatoid arthritis (RA).MethodsThe Medline, Embase and Cochrane Library databases were searched for relevant clinical studies. Studies that assessed the efficacy of denosumab in patients with RA were identified. The primary endpoints were the percent changes in bone mineral density (BMD), and the changes in modified total Sharp score (mTSS), modified Sharp erosion score and joint space narrowing (JSN) score. Pooled analyses were calculated using random-effect models.ResultsAfter searching the literature and performing further detailed assessments, 10 studies with a total of 1758 patients were included in the quantitative analysis. Pooled analyses showed that denosumab treatment significantly increased the percent changes in lumbar spine BMD [mean difference (MD): 5.12, confidence intervals (CI): 4.15 to 6.09], total hip BMD (MD: 2.72, 95% CI: 1.80 to 3.64) and femoral neck BMD (MD: 2.20, 95% CI: 0.94 to 3.46) compared with controls. Moreover, denosumab treatment significantly decreased the changes in mTSS (MD: -0.63, 95% CI: -0.86 to -0.41) and modified Sharp erosion score (MD: -0.62, 95% CI: -0.88 to -0.35). Subgroup analysis indicated that denosumab was superior to bisphosphonates for the improvement of BMD and the mitigation of joint destruction.ConclusionDenosumab treatment was associated with increased BMD and alleviated progression of joint destruction in RA patients, even when compared with bisphosphonates.</p

Quantification of plasma free 3,3′,5-triiodo-l-thyronine (T₃) and free 3,3′,5,5′-l-thyroxine (T₄) contents and the relative mRNA expression levels of hepatic transthyretin (<i>ttr</i>) in female goldfish exposed to 0, 0.01, 0.10, and 1.00 mg/L 40% monocrotophos (MCP) pesticide.

<p>(designated C, MCP0.01, MCP0.10, and MCP1.00, respectively). For panel C, fold change (Y axis) represents the expression of the target gene mRNA relative to that of the control group (equals 1 by definition). The data are presented as the means ± standard deviations (n = 9). Asterisks indicate statistically significant differences from the control group (*0.01<<i>P</i><0.05, **<i>P</i><0.01).</p

Enantioselective 6-<i>exo</i>-Bromoaminocyclization of Homoallylic <i>N</i>‑Tosylcarbamates Catalyzed by a Novel Monophosphine-Sc(OTf)₃ Complex

A highly enantioselective 6-<i>exo</i>-bromoaminocyclization of (<i>E</i>)-homoallylic <i>N</i>-tosylcarbamates catalyzed by a novel monophosphine-Sc­(OTf)₃ complex is described, giving a wide variety of optically active oxazinanones with high enantioselectivities

Relative mRNA expression levels of pituitary thyroid-stimulating hormone <i>β</i> subunit (<i>tshβ</i>) and quantification of plasma TSH content in female goldfish exposed to 0, 0.01, 0.10, and 1.00 mg/L 40% monocrotophos (MCP) pesticide.

<p>(designated C, MCP0.01, MCP0.10, and MCP1.00, respectively). For panel A, fold change (Y axis) represents the expression of the target gene mRNA relative to that of the control group (equals 1 by definition). The data are presented as the means ± standard deviations (n = 9). Asterisks indicate statistically significant differences from the control group (*0.01<<i>P</i><0.05, **<i>P</i><0.01).</p

Pearson correlation coefficients for the plasma thyroid hormone levels and the expression of certain genes related to the hypothalamus-pituitary-thyroid axis.

<p>*Statistically significant at 0.01<<i>P</i><0.05.</p><p>Pearson correlation coefficients for the plasma thyroid hormone levels and the expression of certain genes related to the hypothalamus-pituitary-thyroid axis.</p