201 research outputs found

    Characteristics of study participants by sex from National Health and Nutrition Examination Survey (1999–2004).

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    <p><sup></sup> The description of categorical variable based on non-missing data only.</p

    Growth and Thermophysical Properties of the Nonlinear Optical Crystal LuAl<sub>3</sub>(BO<sub>3</sub>)<sub>4</sub>

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    Single crystals of LuAl<sub>3</sub>(BO<sub>3</sub>)<sub>4</sub> (LuAB) have been grown with the top-seeded solution growth method from a new tungstate based flux Li<sub>2</sub>WO<sub>4</sub>–B<sub>2</sub>O<sub>3</sub>. The crystallization region of LuAB is revealed in a quasi-ternary system of LuAB–Li<sub>2</sub>WO<sub>4</sub>–B<sub>2</sub>O<sub>3</sub>. Correlation between the crystallization region of LuAB and an excess of Al<sub>2</sub>O<sub>3</sub> in the flux system has been identified for the first time. Compared with the commonly used K<sub>2</sub>Mo<sub>3</sub>O<sub>10</sub>–B<sub>2</sub>O<sub>3</sub> flux at 1100 °C, the Li<sub>2</sub>WO<sub>4</sub>–B<sub>2</sub>O<sub>3</sub> flux has lower volatility with lower incorporation of tungstate into the crystals. Thermophysical properties of the crystal have been investigated for the first time, where the thermal expansion coefficients along two crystallographic directions in the temperature range of 30–800 °C were determined to be α<sub>1</sub> = 3.38 × 10<sup>–6</sup> K<sup>–1</sup> and α<sub>3</sub> = 10.4 × 10<sup>–6</sup> K<sup>–1</sup>. The specific heat was about 0.65 J/(g·K) at room temperature. The thermal conductivities at room temperature were 12.47 W/(m·K) and 10.443 W/(m·K) along the <i>a</i> and <i>c</i> axes, respectively, and the Vickers hardness values were measured at 1449 (HV) for (100) and 1595 (HV) for (001) faces

    The standardized regression coefficients of serum C-peptide level for total body and regional bone mineral density from multiple regression analysis stratified by serum insulin level <sup>a</sup>.

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    <p>β coefficients are adjusted for age, sex, ethnicity, height, weight, education level, physical activity, smoking status, alcohol use, triglycerides and creatinine level.<sup></sup> Model 1, the </p><p><sup></sup> Model 2, additionally adjusted for the fasting plasma glucose.</p><p><sup></sup> Model 3, additionally adjusted for the serum alkaline phosphatase.</p><p><sup></sup> Slopes of regression significant at the <0.001 level.</p><p><sup></sup> Slopes of regression significant at the <0.01 level.</p><p><sup></sup> Slopes of regression significant at the <0.05 level.</p><p> = 4,359.<sup>a</sup> Fasting serum insulin, n</p

    The standardized regression coefficients of serum C-peptide level for total body and regional bone mineral density from multiple regression analysis stratified by BMI.

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    <p>β coefficients are adjusted for age, gender, ethnicity, height, weight, education level, physical activity, smoking status, alcohol use, triglycerides and creatinine level.<sup></sup> Model 1, the </p><p><sup></sup> Model 2, additionally adjusted for the fasting plasma glucose.</p><p><sup></sup> Model 3, additionally adjusted for the serum alkaline phosphatase.</p><p><sup></sup> Slopes of regression significant at the <0.001 level.</p><p><sup></sup> Slopes of regression significant at the <0.01 level.</p><p><sup></sup> Slopes of regression significant at the <0.05 level.</p

    Catalytic C6 Functionalization of 2,3-Disubstituted Indoles by Scandium Triflate

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    We report herein an unprecedented direct catalytic C6 functionalization reaction of 2,3-disubstituted indoles with various N–Ts aziridines catalyzed by Sc­(OTf)<sub>3</sub> under mild conditions. Mechanistic studies revealed that a kinetically favored but reversible formal [3 + 2] annulation occurs initially. The direct C6 functionalization, although having a relatively higher energetic barrier, delivers the thermodynamically favorable products

    DataSheet1_Green production information transparency and online purchase behavior: Evidence from green agricultural products in China.pdf

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    The “lemon effect,” which is the result of information asymmetry and barriers to trust, poses serious challenges to the sustainable development of green agricultural products. Therefore, enhancing consumers’ trust is critical to maintain sustainable purchasing behavior. Information transparency has been widely attention as a marketing tool, and previous research related to agricultural products has focused on the visible information. Based on signaling theory, this study takes an invisible information perspective and empirically investigates how production information transparency of green agricultural products affects consumer trust and online purchasing behavior. The results of structural equation modeling analysis show that production technology information transparency and production means information transparency have different effects on the dimensions of consumer trust (in competence and benevolence). Moreover, trust in competence has a significant positive impact on trust in benevolence; they both have significant impacts on consumers’ online green purchase behavior. The results of this study contribute to signaling theory and the product transparency literature, and offer significant implications to practitioners of the green agricultural sectors.</p

    DataSheet_1_The role of MARCH9 in colorectal cancer progression.docx

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    Colorectal cancer (CRC) is the third most common cancer with a high global incidence and mortality. Mutated genes or dysregulated pathways responsible for CRC progression have been identified and employed as biomarkers for diagnosis and prognosis. In this study, a ubiquitination regulator, MARCH9, was shown to accelerate CRC progression both in vitro and in vivo. CRC samples from The Cancer Genome Atlas (TCGA) showed significantly upregulated MARCH9 expression by individual cancer stage, histological subtype, and nodal metastasis status. Knockdown of MARCH9 inhibited, while MARCH9 overexpression promoted, CRC cell proliferation and migration. Knockdown of MARCH9 also induced CRC cell apoptosis and caused cell cycle arrest. Further investigation showed that MARCH9 promoted CRC progression by downregulating the expression of a deubiquitinase cylindromatosis (CYLD) gene and activating p65, a member of the nuclear factor-κB (NF-κB) protein family. Finally, in vivo xenograft studies confirmed that MARCH9 knockdown suppressed tumor growth in nude mice. Thus, this study demonstrated that MARCH9 may be a novel and effective therapeutic target for CRC therapy.</p

    Facet Recognition and Molecular Ordering of Ionic Liquids on Metal Surfaces

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    Ionic liquids are widely used as solvents and reaction media due to low volatility, stability up to high temperature, and large dipole moment. Emergent applications also aim at the anisotropic growth of metal nanostructures in ionic liquids through facet-selective interactions although the governing mechanisms remain poorly understood. We employed a combination of quantum mechanical and classical simulations to analyze the structure and energetics of the self-assembly of ionic liquids on metal surfaces from single ion pairs to multilayers, using the example of 1-ethyl-3-methylimidazolium ethyl sulfate ([EMIM]­[ES]) on the crystallographic {111}, {100}, and {110} facets of gold. Adsorption is controlled by the interplay of soft epitaxy, ionic interactions, induced charges, and steric effects related to the geometry of the cation and anion. These factors lead to characteristic molecular patterns on individual surfaces. Binding energies are similar irrespective of surface coverage and only slightly increase from {111} to {100} and {110} surfaces due to stronger surface corrugation and higher induced charge. The results explain specific experimental observations and aid in understanding particle growth in ionic liquid media. A mechanistic hypothesis for the formation of anisotropic gold nanorods in the presence of silver ions is made, in which silver retards the growth along {100} and {110} facets through underpotential deposition

    Funnel plot for the studies included to analysis the association between NSE concentration and mortality in patients with traumatic brain injury.

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    <p>Funnel plot for the studies included to analysis the association between NSE concentration and mortality in patients with traumatic brain injury.</p
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