Raw data for figures 1-7: Anacardic acid, a histone acetyltransferase inhibitor, modulates LPS-induced IL-8 expression in a human alveolar epithelial cell line A549.

<p>Figure 1: The dose- and time- dependent IL-8 release from A549 cells in vitro.</p> <p>Figure 2: Time course analysis of LPS-mediated IL-8 gene expression in A549 cells in vitro.</p> <p>Figure 3: Time course analysis of LPS-induced histone H4 acetylation at the promoter region of the IL-8 gene in A549 cells in vitro .</p> <p>Figure 4: Effect of TSA on LPS-stimulated IL-8 release from A549 cells in vitro.</p> <p>Figure 5: Time course analysis of TSA on LPS-stimulated IL-8 gene activation from A549 cells in vitro.</p> <p>Figure 6: Effect of anacardic acid on LPS-stimulated IL-8 release from A549 cells in vitro.</p> <p>Figure 7: Time course analysis of anacardic acid on LPS-stimulated IL-8 gene activation in A549 cells in vitro.</p

Mucin (Qniumucin), a Glycoprotein from Jellyfish, and Determination of Its Main Chain Structure

We extracted a novel glycoprotein, a member of the mucin family, from five species of jellyfish with high yields (1%−3% dry weight, 0.02%−0.1% wet weight) and determined its main chain structure and molecular mass. The glycoprotein contains unique tandem repeats of eight amino acids, of which two threonine residues are probably glycosylated by N-acetyl-d-galactosamine (GalNAc). We named this substance, which is common in jellyfish and similar to the human mucin MUC5AC, “qniumucin” and suggested the utilization of this compound as a new marine resource

Correlation Between Pulmonary Function Test Results and Biomarkers and Serum ROM Levels.

Correlation Between Pulmonary Function Test Results and Biomarkers and Serum ROM Levels.</p

Biomarkers and Serum ROM Levels Between Groups With and Without Severe Exacerbation.

<p>Biomarkers and Serum ROM Levels Between Groups With and Without Severe Exacerbation.</p

Correlation between serum reactive oxygen metabolite (ROM) levels and pulmonary function parameters.

<p>(A) Serum ROM levels and þV₁. (B) Serum ROM levels and FEV₁/FVC. þV₁, percent predicted forced expiratory volume in 1 second; FVC, forced vital capacity.</p

Patient Characteristics.

Patient Characteristics.</p

Biomarkers and Serum ROM Levels in Exon 5 Polymorphism of GSTP1 Genotypes.

Biomarkers and Serum ROM Levels in Exon 5 Polymorphism of GSTP1 Genotypes.</p

Correlation between serum reactive oxygen metabolite (ROM) levels and biomarkers.

<p>(A) Serum ROM levels and white blood cell (WBC) count. (B) Serum ROM levels and neutrophil count. (C) Serum ROM levels and eosinophil count. (D) Serum ROM levels and fractional exhaled nitric oxide (FeNO).</p

Receiver operating characteristic curve for serum reactive oxygen metabolite (ROM) levels associated with severe exacerbation in 3 months.

<p>The cutoff level was 358 CARR U. AUC, area under the curve.</p

Correlation Between Serum ROM Levels and Biomarkers.

<p>Correlation Between Serum ROM Levels and Biomarkers.</p