Suun terveys ja krooniset sairaudet

English summar

Mitä lääkärin tulee tietää parodontiitista?

VertaisarvioituRiski sairastua parodontiittiin on yksilöllinen. Taudille altistavat puutteellinen suuhygienia, tupakointi ja huonossa hoitotasapainossa oleva diabetes. Diagnosointi edellyttää hammaslääkärin kliinistä ja röntgenologista tutkimusta. Parodontiitin hoidossa on keskeistä hampaan pintojen ja syventyneiden ientaskujen mekaaninen puhdistus sekä tupakasta vieroittaminen. Hoitamaton tauti pahentaa ja ylläpitää elimistön subkliinistä systeemistä tulehdustilaa, joka vaikuttaa moniin yleissairauksiin.Peer reviewe

Kuppa kummittelee suussa

Vertaisarvioitu. Näin hoidan.Lähes kaikki sukupuolitaudit voivat esiintyä ensimmäisenä myös suun limakalvoilla ja aiheuttaa epäspesifisiä oireita, esimerkiksi haavaumia. Siksi suun ja nielun limakalvojen kliiniseen näkymään ja oireisiin tulee kiinnittää huomiota ja muistaa myös sukupuolitautien mahdollisuus erotusdiagnostiikassa. Kymmenen viime vuoden aikana kuppahavaintojen määrä on lisääntynyt maailmanlaajuisesti, ja tämä on liittynyt erityisesti miesten väliseen seksiin. Primaarivaiheessa kuppa ilmenee suussa aristamattomana, kovareunaisena haavaumana. Diagnosointi on hankalaa tapauksissa, joissa kuppahaavoja esiintyy ainoastaan suuontelossa eikä potilaan anamneesin perusteella herää epäilyä sukupuolitaudin mahdollisuudesta

SNP Analysis of Caries and Initial Caries in Finnish Adolescents

Background. Dental caries is the most common infection in the world and is influenced by genetic and environmental factors. Environmental factors are largely known, but the role of genetic factors is quite unknown. The aim was to investigate the genetic background of caries in Finnish adolescents. Materials and Methods. This study was carried out at the Kotka Health Center in Eastern Finland. 94 participants aged 15-17 years gave approval for the saliva and DNA analyses. However, one was excluded in DNA analysis; thus, the overall number of participants in analysis was 93. Caries status was recorded clinically and from bite-wing X-rays to all 94 participants. Genomic DNA was extracted by genomic QIAamp (R) DNA Blood Mini Kit and genotyped for polymorphisms. The results were analyzed using additive and logistic regression models. Results. No significant associations between caries and the genes studied were found. However, SNPs in DDX39B and MPO showed association tendencies but were not statistically significant after false discovery rate (FDR) analysis. SNPs in VDR, LTA, and MMP3 were not statistically significant with initial caries lesions after FDR analysis. Conclusion. The present study could not demonstrate statistically significant associations between caries and the genes studied. Further studies with larger populations are needed.Peer reviewe

Oral symptoms and oral health-related quality of life in patients with chronic kidney disease from predialysis to posttransplantation

ObjectiveThis prospective follow-up cohort study analyzed chronic kidney disease (CKD) patients' oral symptoms, health habits, and oral health-related quality of life (OHRQoL), from predialysis to posttransplantation. A simplified questionnaire method (Oral Health Quality Score, OHQS), based on these and clinical findings, was constructed and tested for identifying patients in need for referral to a dentist.Material and methodsFifty-three CKD patients were followed up for a mean of 10.3years. Clinical oral, radiological, and salivary examination was performed at baseline and posttransplantation. Total Dental Index (TDI) indicating inflammation was calculated. The patients filled out a questionnaire on symptoms, oral hygiene and health care habits, smoking, alcohol use, and medication. General health-related quality of life was assessed with the 15-dimensional (15D) instrument at posttransplantation. Descriptive and analytical methods were used in statistics.ResultsOHQS significantly correlated with high TDI (p=0.017), number of teeth (p=0.031), and unstimulated salivary flow rate (p=0.001) in transplanted patients. Number of daily medications showed a negative correlation with the OHQS (r=-0.30; p=0.028). The prevalence of oral symptoms was slightly, but not significantly, more common posttransplantation compared with predialysis stage.ConclusionOHQS identified patients with high oral inflammatory score thus confirming our study hypothesis.Clinical relevanceUse of OHQS and measuring salivary flow indicate patients at risk for oral diseases. These markers might be easy to use chair-side also by auxiliary personnel.Peer reviewe