Sensitivities and positive predictive values for detection of severe pneumococcal pneumonia (Pneumonia Severity Index risk class IV-V) at different nasopharyngeal DNA density cut-off levels.

<p>^a Data presented as % (patients with severe pneumococcal pneumonia and DNA density ≥ cut-off/all patients with severe pneumococcal pneumonia).</p><p>^b Data presented as % (patients with severe pneumococcal pneumonia and DNA density ≥ cut-off /all patients with DNA density ≥ cut-off).</p><p>Sensitivities and positive predictive values for detection of severe pneumococcal pneumonia (Pneumonia Severity Index risk class IV-V) at different nasopharyngeal DNA density cut-off levels.</p

Flow chart of the study population with and without nasopharyngeal aspirate tested with PCR for pneumococcal DNA.

<p>Flow chart of the study population with and without nasopharyngeal aspirate tested with PCR for pneumococcal DNA.</p

Factors and their independent association with nasopharyngeal pneumococcal density.

<p>Regression analysis with bootstrapping in 47 patients with complete information about the included parameters.</p

Clinical and microbiological factors and their association with nasopharyngeal pneumococcal density.

<p>^a Solid tumor, blood malignancy, liver disease, renal disease, chronic obstructive pulmonary disease, heart disease, stroke, diabetes.</p><p>^b Serotypes 3, 6B, 11A, 12F, 19A, 19F, 23F, and 35B.</p><p>Univariate analysis on 57 patients if not otherwise stated.</p

Characteristics of patients with community-acquired pneumonia with pneumococcal DNA detected and not detected in nasopharyngeal (NP) aspirate.

<p>Data are presented as numbers (%), unless otherwise indicated.</p><p>^a<i>Streptococcus pneumoniae</i> detected by blood culture and/or culture of respiratory secretions and/or urinary antigen test.</p><p>^b Solid tumor, blood malignancy, liver disease, renal disease, chronic obstructive pulmonary disease, heart disease, stroke, diabetes.</p><p>Characteristics of patients with community-acquired pneumonia with pneumococcal DNA detected and not detected in nasopharyngeal (NP) aspirate.</p