1,385 research outputs found
Phenomenological theory of the giant magnetoimpedance of composite wires
Composite wires with a three-layered structure are known to show a
particularly large magnetoimpedance effect. The wires consist of a highly
conductive core, an insulating layer and an outer ferromagnetic shell. In order
to understand the origin of the effect a theory based on a coupling of the
Maxwell equations to the Landau-Lifschitz-Gilbert equation is suggested. The
theory is phenomenological in the sense that it does not account for a domain
structure. However, theoretical results nicely reproduce those obtained in
various measurements. Furthermore, an upper limit of the magnetoimpedance ratio
for a given combination of materials can be determined.Comment: 4 pages, figure
Influence of Immune Status on the Airborne Colonization of Piglets with Methicillin-Resistant Staphylococcus aureus (MRSA) Clonal Complex (CC) 398
Colonized vertebrates including humans and pigs are to date the main reservoirs of livestock-associated Methicillin-resistant Staphylococcus aureus (LA-MRSA). Currently, the mechanisms underlying colonization of pigs are not fully understood.
We investigated the influence of piglet pre-immune status on airborne MRSA colonization. Three groups of MRSA-negative piglets were primed and exposed to airborne LA-MRSA (104 colony forming units (cfu)/m3) in an aerosol chamber for 24 h. One group was treated intramuscularly with dexamethasone (1 mg/kg body weight) to imitate weaning stress. The second group was exposed to bacterial endotoxin containing MRSA aerosol. Both conditions play a role in the development of multifactorial diseases and may promote MRSA colonization success. The third group served as control.
The piglets' MRSA status was monitored for 21 days via swab samples. At necropsy, specific tissues and organs were analyzed. Blood was collected to examine specific immunological parameters.
The duration of MRSA colonization was not extended in both treated groups compared to the control group, indicating the two immune-status influencing factors do not promote MRSA colonization. Blood sample analysis confirmed a mild dexamethasone-induced immune suppression and typical endotoxin-related changes in peripheral blood. Of note, the low-dose dexamethasone treatment showed a trend of increased MRSA clearance
Hybrid model decomposition of speech and noise in a radial basis function neural model framework
Transport control of dust particles via the Electrical Asymmetry Effect: experiment, simulation, and modeling
The control of the spatial distribution of micrometer-sized dust particles in
capacitively coupled radio frequency discharges is relevant for research and
applications. Typically, dust particles in plasmas form a layer located at the
sheath edge adjacent to the bottom electrode. Here, a method of manipulating
this distribution by the application of a specific excitation waveform, i.e.
two consecutive harmonics, is discussed. Tuning the phase angle \theta between
the two harmonics allows to adjust the discharge symmetry via the Electrical
Asymmetry Effect (EAE). An adiabatic (continuous) phase shift leaves the dust
particles at an equilibrium position close to the lower sheath edge. Their
levitation can be correlated with the electric field profile. By applying an
abrupt phase shift the dust particles are transported between both sheaths
through the plasma bulk and partially reside at an equilibium position close to
the upper sheath edge. Hence, the potential profile in the bulk region is
probed by the dust particles providing indirect information on plasma
properties. The respective motion is understood by an analytical model, showing
both the limitations and possible ways of optimizing this sheath-to-sheath
transport. A classification of the transport depending on the change in the dc
self bias is provided, and the pressure dependence is discussed.Comment: 25 pages, 16 figure
Minimum Weight Flat Antichains of Subsets
Building on classical theorems of Sperner and Kruskal-Katona, we investigate
antichains in the Boolean lattice of all subsets of
, where is flat, meaning that it contains
sets of at most two consecutive sizes, say , where contains only -subsets,
while contains only -subsets. Moreover, we assume
consists of the first -subsets in squashed
(colexicographic) order, while consists of all -subsets
not contained in the subsets in . Given reals , we
say the weight of is
. We characterize the minimum
weight antichains for any given , and we do the
same when in addition is a maximal antichain. We can then derive
asymptotic results on both the minimum size and the minimum Lubell function
Fischereiforschungskutter "Clupea" 50 Jahre
Der seit 1. Januar 1992 vom damaligen Bundesamt für Ernährung und Forstwirtschaft, der heutigen Bundesanstalt
für Landwirtschaft und Ernährung (BLE) bereederte und für Arbeiten der Bundesforschungsanstalt für Fischerei (BFAFi) verfügbare Fischereiforschungskutter (FFK) „Clupea“ wurde vor 50 Jahren am 7. November 1949 als Fischereikutter SAS 115 „Erfurt“ in Saßnitz in Dienst gestellt. Nach der Verlagerung einiger 17-m-Kutter an den Standort Karlshagen auf Usedom wurde daraus die „WOG 83“ (1955) und später die „KAR23“. Die „Erfurt“ wurde als Gespannpartner in der Heringsfischerei sowie autonom im Dorsch- und Plattfischfang mit Schleppnetzen eingesetzt
Prolactin secretory rhythm in women: immediate and long-term alterations after sexual contact
BACKGROUND Prolactin (PRL) is one of the most versatile hormones in the mammalian body, affecting reproductive, sexual and other functions. In rats, mating or vaginocervical stimulation activates a characteristic PRL secretory pattern for several days, which is essential for successful reproduction. Although the underlying mechanisms appear to be different, PRL is also crucial for human fertility. We have detected a PRL increase in women induced by sexual intercourse. Extending these findings, the current study aimed at analyzing the PRL secretory rhythm after sexual contact, in order to elucidate whether human females also show long-term alterations of the PRL secretory pattern. METHODS In a pilot study, serial blood samples were taken from women (n= 7) in mid-cycle to assess changes in PRL secretory rhythm induced by sexual intercourse, during a period of 32 h. RESULTS Compared with control condition, sexual intercourse with orgasm induced not only the well-established immediate PRL increase of ∼300% but also an additional PRL elevation around noon of the next day (P< 0.05). These fluctuations were measured on top of the regular circadian rhythm of PRL, manifested as a surge early in the morning. CONCLUSIONS We are able to demonstrate a long-term change in the PRL secretory rhythm after sexual intercourse with orgasm in females, suggesting memory effects. We hypothesize that the additionally secreted PRL could be beneficial for decidualization and implantation. Further studies with more participants are required to investigate in detail the implications of such effects on reproductive success in human
Web-based patient-reported outcomes using the International Consortium for Health Outcome Measurement dataset in a major German university hospital: observational study
Background: Collecting patient-reported outcome (PRO) data systematically enables objective evaluation of treatment and its related outcomes. Using disease-specific questionnaires developed by the International Consortium for Health Outcome Measurement (ICHOM) allows for comparison between physicians, hospitals, and even different countries. Objective: This pilot project aimed to establish a digital system to measure PROs for new patients with breast cancer who attended the Charité Breast Center. This approach should serve as a blueprint to further expand the PRO measurement to other disease entities and departments. Methods: In November 2016, we implemented a Web-based system to collect PRO data at Charité Breast Center using the ICHOM dataset. All new patients at the Breast Center were enrolled and answered a predefined set of questions using a tablet computer. Once they started their treatment at Charité, automated emails were sent to the patients at predefined treatment points. Those emails contained a Web-based link through which they could access and answer questionnaires. Results: By now, 541 patients have been enrolled and 2470 questionnaires initiated. Overall, 9.4% (51/541) of the patients were under the age of 40 years, 49.7% (269/541) between 40 and 60 years, 39.6% (214/541) between 60 and 80 years, and 1.3% (7/541) over the age of 80 years. The average return rate of questionnaires was 67.0%. When asked about the preference regarding paper versus Web-based questionnaires, 6.0% (8/134) of the patients between 50 and 60 years, 6.0% (9/150) between 60 and 70 years, and 12.7% (9/71) over the age of 70 years preferred paper versions. Conclusions: Measuring PRO in patients with breast cancer in an automated electronic version is possible across all age ranges while simultaneously achieving a high return rate
- …
