18,782 research outputs found

    Anthropological Linguistics (LING21, ANTH020N) Syllabus

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    Anthropological Linguistics course description:Communication and culture mutually define one another across communities worldwide. Human linguistic diversity, language contact and language change, and face-to-face communication continue to be key areas of inquiry for both linguistics and anthropology. Colonialism, globalization, mobility, and new technologies are changing the way we transmit and conceive of cultural knowledge, community, and our selves and the natural environment. In this course we draw attention to codeswitching, creoles, language endangerment, and constructed languages as reflections of our changing societies. We also address the ethics of fieldwork as a means of investigating these important social phenomena at the interfaces of language/ecology, language/identity, Global North/South

    Getting Started With COCA

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    In this assignment, students will learn basic methods in corpus linguistics, an emerging field at the intersection of humanities and quantitative social science. They will learn how to search large English language corpora (e.g., the 900 million word Cambridge International Corpus) to look for otherwise hidden patterns of language use. They will be able to track the emergence of new words, shifts in meaning in existing words, and note the obsolescence of some words. They will interpret their findings in light of how language usage reflects societal attitudes and social change

    Photonic integration platform with pump free microfluidics

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    Chip based particle sensing using 3D capillary fill microfluidics integrated with monolithically integrated lasers and photodetectors is used to demonstrate the feasibility of true chip scale photonic measurements of fluids. The approach is scalable and manufactured using industry standard compound semiconductor fabrication tools. The need for fluid speed regulation via external pumps is removed by measuring local particle velocity at the point of interrogation and particle position within the fluid flow is derived from multiple time resolved forward scattered light signals. Particle size discrimination of 10 and 15 μm polystyrene microbeads is used as an example

    ADAS analysis of the differential emission measure structure of the inner solar corona. II. A study of the `quiet Sun' inhomogeneities from SOHO CDS-NIS spectra

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    We present a study of the differential emission measure (DEM) of a `quiet Sun' area observed in the extreme ultraviolet at normal incidence by the Coronal Diagnostic Spectrometer (CDS) on the SOHO spacecraft. The data used for this work were taken using the NISAT_S observing sequence. This takes the full wavelength ranges from both the NIS channels (308-381 Angtr. and 513-633 Angst.) with the 2 arcsec by 240 arcsec slit, which is the narrowest slit available, yielding the best spectral resolution. In this work we contrast the DEM from subregions of 2 by 80 arcsec2^2 with that obtained from the mean spectrum of the whole raster (20 by 240 arcsec2^2). We find that the DEM maintains essentially the same shape in the subregions, differing by a constant factor between 0.5 and 2 from the mean DEM, except in areas were the electron density is below 2×1072 \times 10^7 cm3^{-3} and downflow velocities of 50 km/s are found in the transition region. Such areas are likely to contain plasma departing from ionisation equilibrium, violating the basic assumptions underlying the DEM method. The comparison between lines of Li-like and Be-like ions may provide further evidence of departure from ionisation equilibrium. We find also that line intensities tend to be lower where velocities of the order of 30 km/s or higher are measured in transition region lines. The DEM analysis is also exploited to improve the line identification performed by Brooks et al (1999) and to investigate possible elemental abundance variations from region to region. We find that the plasma has composition close to photospheric in all the subregions examined.Comment: 18 pages, 9 figures, 7 tables. Table 5 is available only online. A copy of Table 5 can be found at http://webusers.ct.astro.it/acl/table5.dat. The ReadMe file is at http://webusers.ct.astro.it/acl/ReadMe. Accepted by Astronomy and Astrophysic

    The Nature of the Secondary Star in the Black Hole X-Ray Transient V616 Mon (=A0620-00)

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    We have used NIRSPEC on Keck II to obtain KK-band spectroscopy of the low mass X-ray binary V616 Mon (= A0620-00). V616 Mon is the proto-typical soft x-ray transient containing a black hole primary. As such it is important to constrain the masses of the binary components. The modeling of the infrared observations of ellipsoidal variations in this system lead to a derived mass of 11.0 M_{\sun} for the black hole. The validity of this derivation has been called into question due to the possiblity that the secondary star's spectral energy distribution is contaminated by accretion disk emission (acting to dilute the variations). Our new KK-band spectrum of V616 Mon reveals a late-type K dwarf secondary star, but one that has very weak 12^{\rm 12}CO absorption features. Comparison of V616 Mon with SS Cyg leads us to estimate that the accretion disk supplies only a small amount of KK-band flux, and the ellipsoidal variations are not seriously contaminated. If true, the derived orbital inclination of V616 Mon is not greatly altered, and the mass of the black hole remains large. A preliminary stellar atmosphere model for the KK-band spectrum of V616 Mon reveals that the carbon abundance is approximately 50% of the solar value. We conclude that the secondary star in V616 Mon has either suffered serious contamination from the accretion of supernova ejecta that created the black hole primary, or it is the stripped remains of a formerly more massive secondary star, one in which the CNO cycle had been active.Comment: 20 pages, 5 figure

    Hypomethylation of CYP2E1 and DUSP22 Promoters Associated With Disease Activity and Erosive Disease Among Rheumatoid Arthritis Patients.

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    OBJECTIVE:Epigenetic modifications have previously been associated with rheumatoid arthritis (RA). In this study, we aimed to determine whether differential DNA methylation in peripheral blood cell subpopulations is associated with any of 4 clinical outcomes among RA patients. METHODS:Peripheral blood samples were obtained from 63 patients in the University of California, San Francisco RA cohort (all satisfied the American College of Rheumatology classification criteria; 57 were seropositive for rheumatoid factor and/or anti-cyclic citrullinated protein). Fluorescence-activated cell sorting was used to separate the cells into 4 immune cell subpopulations (CD14+ monocytes, CD19+ B cells, CD4+ naive T cells, and CD4+ memory T cells) per individual, and 229 epigenome-wide DNA methylation profiles were generated using Illumina HumanMethylation450 BeadChips. Differentially methylated positions and regions associated with the Clinical Disease Activity Index score, erosive disease, RA Articular Damage score, Sharp score, medication at time of blood draw, smoking status, and disease duration were identified using robust regression models and empirical Bayes variance estimators. RESULTS:Differential methylation of CpG sites associated with clinical outcomes was observed in all 4 cell types. Hypomethylated regions in the CYP2E1 and DUSP22 gene promoters were associated with active and erosive disease, respectively. Pathway analyses suggested that the biologic mechanisms underlying each clinical outcome are cell type-specific. Evidence of independent effects on DNA methylation from smoking, medication use, and disease duration were also identified. CONCLUSION:Methylation signatures specific to RA clinical outcomes may have utility as biomarkers or predictors of exposure, disease progression, and disease severity

    Investigating whether adverse prenatal and perinatal events are associated with non-clinical psychotic symptoms at age 12 years in the ALSPAC birth cohort

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    Background. Non-clinical psychosis-like symptoms (PLIKS) occur in about 15% of the population. It is not clear whether adverse events during early development alter the risk of developing PLIKS. We aimed to examine whether maternal infection, diabetes or pre-eclampsia during pregnancy, gestational age, perinatal cardiopulmonary resuscitation or 5-min Apgar score were associated with development of psychotic symptoms during early adolescence. Method. A longitudinal study of 6356 12-year-old adolescents who completed a semi-structured interview for psychotic symptoms in the Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort. Prenatal and perinatal data were obtained from obstetric records and maternal questionnaires completed during pregnancy. Results. The presence of definite psychotic symptoms was associated with maternal infection during pregnancy [adjusted odds ratio (OR) 1.44, 95% confidence interval (CI) 1.11–1.86, p=0.006], maternal diabetes (adjusted OR 3.43, 95% CI 1.14–10.36, p=0.029), need for resuscitation (adjusted OR 1.50, 95% CI 0.97–2.31, p=0.065) and 5-min Apgar score (adjusted OR per unit decrease 1.30, 95% CI 1.12–1.50, p<0.001). None of these associations were mediated by childhood IQ score. Most associations persisted, but were less strong, when including suspected symptoms as part of the outcome. There was no association between PLIKS and gestational age or pre-eclampsia. Conclusions. Adverse events during early development may lead to an increased risk of developing PLIKS. Although the status of PLIKS in relation to clinical disorders such as schizophrenia is not clear, the similarity between these results and findings reported for schizophrenia indicates that future studies of PLIKS may help us to understand how psychotic experiences and clinical disorders develop throughout the life-course

    GALEX, Optical and IR Light Curves of MQ Dra: UV Excesses at Low Accretion Rates

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    Ultraviolet light curves constructed from NUV and FUV detectors on GALEX reveal large amplitude variations during the orbital period of the Low Accretion Rate Polar MQ Dra (SDSSJ1553+55). This unexpected variation from a UV source is similar to that seen and discussed in the Polar EF Eri during its low state of accretion, even though the accretion rate in MQ Dra is an order of magnitude lower than even the low state of EF Eri. The similarity in phasing of the UV and optical light curves in MQ Dra imply a similar location for the source of light. We explore the possibilities of hot spots and cyclotron emission with simple models fit to the UV, optical and IR light curves of MQ Dra. To match the GALEX light curves with a single temperature circular hot spot requires different sizes of spots for the NUV and FUV, while a cyclotron model that can produce the optical harmonics with a magnetic field near 60 MG requires multipoles with fields > 200 MG to match the UV fluxes.Comment: accepted for ApJ; 15 pages, 7 tables, 8 fig
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