12,602 research outputs found
Who are the Self-employed? A New Approach
Whilst the individual supply-side characteristics of the self-employed are well documented, the literature has largely neglected (or mis-specified) demand-side aspects. Our econometric framework, based on the parameterised DOGEV model, allows us to separately, and simultaneously, model supply and demand-side influences. We show that whilst individual characteristics are important determinants of type of employment contract held, there are important contract-specific factors influencing the contract an individual is employed under. Our results suggest that workers may be "captive" to particular types of employment because of the sectors in which they work, the number of hours they prefer to work and their ethnicity.self-employment, captivity
Quantum-assisted biomolecular modelling
Our understanding of the physics of biological molecules, such as proteins
and DNA, is limited because the approximations we usually apply to model inert
materials are not in general applicable to soft, chemically inhomogeneous
systems. The configurational complexity of biomolecules means the entropic
contribution to the free energy is a significant factor in their behaviour,
requiring detailed dynamical calculations to fully evaluate. Computer
simulations capable of taking all interatomic interactions into account are
therefore vital. However, even with the best current supercomputing facilities,
we are unable to capture enough of the most interesting aspects of their
behaviour to properly understand how they work. This limits our ability to
design new molecules, to treat diseases, for example. Progress in biomolecular
simulation depends crucially on increasing the computing power available.
Faster classical computers are in the pipeline, but these provide only
incremental improvements. Quantum computing offers the possibility of
performing huge numbers of calculations in parallel, when it becomes available.
We discuss the current open questions in biomolecular simulation, how these
might be addressed using quantum computation and speculate on the future
importance of quantum-assisted biomolecular modelling.Comment: 10 + epsilon pages, 2 figure
Blurring the Margins: Ardalén (2012) and Collective Memory in Spain
The title of Miguelanxo Prado's Ardalén is a word invented by its author, but which refers to a real phenomenon: a long-distance wind that carries the scent of salt and sea far inland from the coast. In the fictional tale, this sea breeze carries with it not just air and smells, but also stories, as well as living sea creatures. Appropriate to its title, this winner of the 2012 National Spanish Comics Prize blurs lines between the real and the imaginary, between self and other, between land and sea, and between life and death. Blurry margins exist metaphorically in the book's story as well as visually in its images, both within its panels and in its gutters. Drawing on Anne Whitehead's recent discussion of modes of inscription and collective memory, this article explores the representation of memory and the fantastic in Miguelanxo Prado's 2012 graphic novel Ardalén, noting the strong implications of Ardalén's main character's incapacity to distinguish between what he lived and what he heard in the context of the Recovery of Historical Memory in Spain's early 21st century.The title of Miguelanxo Prado's Ardalén is a word invented by its author, but which refers to a real phenomenon: a long-distance wind that carries the scent of salt and sea far inland from the coast. In the fictional tale, this sea breeze carries with it not just air and smells, but also stories, as well as living sea creatures. Appropriate to its title, this winner of the 2012 National Spanish Comics Prize blurs lines between the real and the imaginary, between self and other, between land and sea, and between life and death. Blurry margins exist metaphorically in the book's story as well as visually in its images, both within its panels and in its gutters. Drawing on Anne Whitehead's recent discussion of modes of inscription and collective memory, this article explores the representation of memory and the fantastic in Miguelanxo Prado's 2012 graphic novel Ardalén, noting the strong implications of Ardalén's main character's incapacity to distinguish between what he lived and what he heard in the context of the Recovery of Historical Memory in Spain's early 21st century.La novela gráfica Ardalén (2012) de Miguelanxo Prado se titula con una palabra inventada por su autor, pero que se refiere a un fenómeno verdadero: un viento de larga distancia que lleva el olor de la sal y del mar lejos de la costa al interior del país. En la novela gráfica, esta brisa marina lleva consigo no sólo sus aires y sus olores, sino también historias, recuerdos, así como criaturas marinas vivas. Apropiado a su título, este libro ganador del Premio Nacional de Cómic de 2012 borra fronteras entre lo real y lo imaginario, entre persona y colectividad, entre tierra y mar, y entre vida y muerte. Los márgenes borrosos existen metafóricamente en la historia del libro, así como visualmente en sus imágenes, tanto dentro de sus viñetas como en los espacios entre sus vi- ñetas. Basándose en el reciente análisis de Anne Whitehead sobre los modos de inscripción y la memoria colectiva, el presente artículo explora la representación de la memoria y lo fantástico en la novela gráfica Ardalén de Miguelanxo Prado, señalando las fuertes implicaciones de la incapacidad del protagonista en Ardalén de distinguir entre lo que vivió y lo que oyó contar en el contexto de la Recuperación de la Memoria Histórica en el siglo xxi de España
‘Unfettered expression of thought’? Experiences of anonymous online role play
Advocates suggest that anonymity allows all learners to have an equal voice in a learning environment, and that it encourages participation. This paper explores tutors’ and learners’ experiences of an anonymous, synchronous role play activity conducted using online discussion forums. A qualitative study was undertaken to investigate the experiences of five groups of learners and four tutors. Data were obtained from an online questionnaire and interviews with students and tutors. The findings reveal a huge diversity in responses to the activity. Learners’ emotions before the activity ranged from ‘confident’ to ‘panic’. Afterwards many stated that ‘anonymity’ was the best thing about the activity, suggesting that it ‘loosened inhibitions’ and allowed ‘unfettered expression of thought’. At the same time, some respondents admitted trying to guess the identity of participants, and played their roles with varying degrees of conviction and engagement. Some participants may even have refrained from playing any part in the activity, hiding behind their anonymity. For tutors issues of control were significant and issues of facilitation were raised, although inappropriate behaviour was rare. This study has revealed the diversity of learners’ responses to online role play, and the generally positive attitude towards anonymity. It also highlights the potential for anonymity to contribute to inequality in participation and raises the question of whether genuine anonymity can be useful or achievable. Key findings with significance for future implementation of similar role play activities are presented here
Reproductive performance of resident and migrant males, females and pairs in a partially migratory bird
We thank everyone from the Centre for Ecology & Hydrology (CEH) who contributed to data collection, and Scottish Natural Heritage for access to the Isle of May National Nature Reserve. We thank the Scottish Ornithologists’ Club (SOC) for their support, and all volunteer observers, particularly Raymond Duncan, Moray Souter and Bob Swann. HG was funded by a Natural Environment Research Council (NERC) CASE studentship supported by CEH and SOC, FD, SW, MPH, MN and SB were funded by NERC and the Joint Nature Conservation Committee, and JMR was part-funded by the Royal Society. Finally, we thank the Associate Editor and two reviewers for constructive comments on the manuscript. The data are available from the Dryad Digital Repository https://doi.org/10.5061/dryad.532j0 (Grist et al., 2017)Peer reviewedPublisher PD
Obesity prevalence and associated risk factors in outdoor living domestic horses and ponies
Reasons for performing study. The prevalence of obesity in companion animals, including horses and ponies has risen drastically in recent years and risk factors have been little investigated. Horses are unique amongst companion animals in that many are outdoor-living and forage independently on pasture; they also have a dual utility and companionship role. The body condition of wild and free-living equines is known to vary seasonally, yet previous estimates of the prevalence of obesity and associated risk factors in domestic animals do not consider this. Most previous studies were conducted during the summer months when pasture quality is greater and obesity prevalence is likely to be highest. In addition, many previous estimates do not use validated body condition scoring methods and rely on owner reporting.Objectives. To examine the prevalence and risk factors predictive of equine obesity at both the end of winter and the end of summer, in a domestic population of leisure horses with daily access to pasture. Using validated body condition scoring methods and a single, trained observer.Methods. Body condition and belly girth measurements were taken at the end of winter and during the summer in a population of leisure horses (n = 96) with outdoor pasture access for ≥6 h per day. Risk factor information was obtained by two owner questionnaires and analysed statistically using a mixed effects logistic regression model. The dependent variable was obese (BCS ≥ 7/9) or non-obese (BCS < 7/9). Risk factors associated with seasonal change in belly girth were also explored using a mixed effects linear regression model.Results. Obesity prevalence rose significantly from 27.08% at the end of winter to 35.41% during summer (p < 0.001). Breed was the risk factor most strongly associated with obesity (p < 0.001). Supplementary feed was not a strong predictor and there was no association with low intensity structured exercise. As winter BCS increased, the percentage seasonal change in belly girth decreased.Conclusions. Obesity prevalence differed between winter and summer in domestic equines. Supplementary feed and low intensity structured exercise in equines living outdoors for ≥6 h per day had limited or no effect on obesity levels. Seasonal variation in body condition was lower in obese equines.Potential relevance. It is important to consider season when studying equine obesity and obesity-associated disorders. Risk factor analysis suggests preventative measures may need to be breed specific. The metabolic implications of a lessened seasonal change in body condition in obese animals, warrants investigation
A Langmuir approach on monolayer interactions to investigate surface active peptides
The Langmuir Blodgett apparatus provides a versatile system for studying the interfacial properties of peptides and peptide-membrane interactions under controlled conditions. Using amphiphilic α-helical peptides to highlight studies undertaken, here we discuss the use of this system to provide information on the surface activity of peptides and describe the insights these studies give into biological functio
Material choices for fibre in the Neolithic: an approach through the measurement of mechanical properties
Studies of the Mesolithic-Neolithic transition in Europe have focused on plants and animals exploited for food. However, the exploitation of plants for fibres underwent a significant change with the addition of domestic flax as a fibre crop. While the technology of flax fibre processing is increasingly understood by archaeologists, its material value as a fibre crop in comparison to indigenous fibre is less well explored. We examine the mechanical properties of flax and two indigenous fibres (lime bast, willow bast), by testing fibre strips for tensile properties and discuss the results in the light of material choices in these periods
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