Self-Catalyzed, Visible-Light-Induced Selective C3–H Aroylation of Quinoxalin-2(1<i>H</i>)‑ones with Arylaldehydes by Air as an Oxidant

A self-catalyzed, visible-light-induced, directly selective C3–H aroylation of quinoxalin-2(1H)-ones via energy transfer and hydrogen atom transfer (HAT) catalysis has been developed. The method is highly atom-economical, eco-friendly, and easy to handle. Notably, the reaction proceeded efficiently with ambient air as the sole oxidant at room temperature

Nitrogen-Doped Carbon Dot and CdTe Quantum Dot Dual-Color Multifunctional Fluorescent Sensing Platform: Sensing Behavior and Glucose and pH Detection

A novel fluorescent probe based on a nitrogen-doped carbon dot (N-CD) and CdTe quantum dot (CdTe QD) platform has been constructed for H2O2/glucose detection and pH sensing. In this work, H2O2-tolerant blue fluorescence N-CDs were added to the H2O2-mediated yellow fluorescence quenching of CdTe QDs to construct a dual-color ratiometric fluorescent H2O2 probe. H2O2-induced passivated group detachment and action on deep nanocrystals promoted CdTe QD fluorescence quenching. Meanwhile, the addition of the blue fluorescent background of N-CDs sharply reflected the color change in CdTe QDs. Under the optimized experimental conditions, the platform was effectively applied to the detection of H2O2 produced by the enzymatic reaction of glucose, showing high sensitivity (limit of detection 7.86 μM) and wide linear range (26–900 μM) for glucose detection. The pH-sensing behavior of CdTe QDs and N-CDs was attributed to the displacement of a weak acid (3-mercaptopropionic acid) by a strong acid (HCl) and the acid titration process of two coexisting bases (N-CDs and NH3·H2O), respectively. The loss of passivation and doping effects led to a decrease in the fluorescence intensity of CdTe QDs and N-CDs. Moreover, utilizing the ability of bimaterial system fluorescence to pH sensing, a semiquantitative pH detection based on the linear response was developed. The pH range was analyzed by three kinds of N-CD (Fex = 440 nm) and CdTe QD (Fex = 548 nm) typical emission spectral shapes. In addition, the recovery results showed that the bimaterial system was proved to be appropriate for the assay of glucose in spiked serum samples

Mechanochemical Modification of Oxygen/Nitrogen Species on Surface of Hard Carbon for Improved Sodium Storage

Oxygen and nitrogen are common but efficient heteroatoms for carbon materials to enhance electronic conductivity and electrochemical reactivity. The carbon–oxygen and carbon–nitrogen bonds are significant for the electrochemical performance of the doped carbon. Among these, CO groups and pyridinic-N have been widely recognized as the most active adsorption sites for Na+. In this work, the percentages of active O/N species on the surface have been regulated by a mechanochemical approach. The high content of CO groups along with pyridinic-N can be achieved in N-doped carbon nanospheres (NCS). NCS as an anode thus delivers a capacity of 281.6 mA h g–1 at 0.03 A g–1 after 120 cycles, which is enhanced by 75.1% in comparison to the untreated sample. It retains 134.9 mA h g–1 at 1 A g–1 up to 2000 cycles. The enhanced sodium storage properties are created by plentiful sodium adsorption sites, including CO groups and defects, and good electronic conductivity induced by pyridinic-N. The present work should supply a reference for adjusting heteroatoms on carbonaceous materials and their application in the energy storage field

Novel EIicitin from Pythium oligandrum Confers Disease Resistance against Phytophthora capsici in Solanaceae Plants

The mycoparasite Pythium oligandrum is a nonpathogenic oomycete that can boost plant immune responses. Elicitins are microbe-associated molecular patterns (MAMPs) specifically produced by oomycetes that activate plant defense. Here, we identified a novel elicitin, PoEli8, from P. oligandrum that exhibits immunity-inducing activity in plants. In vitro-purified PoEli8 induced strong innate immune responses and enhanced resistance to the oomycete pathogen Phytophthora capsici in Solanaceae plants, including Nicotiana benthamiana, tomato, and pepper. Cell death and reactive oxygen species (ROS) accumulation triggered by the PoEli8 protein were dependent on the plant coreceptors receptor-like kinases (RLKs) BAK1 and SOBIR1. Furthermore, REli from N. benthamiana, a cell surface receptor-like protein (RLP) was implicated in the perception of PoEli8 in N. benthamiana. These results indicate the potential value of PoEli8 as a bioactive formula to protect Solanaceae plants against Phytophthora

Novel EIicitin from Pythium oligandrum Confers Disease Resistance against Phytophthora capsici in Solanaceae Plants

The mycoparasite Pythium oligandrum is a nonpathogenic oomycete that can boost plant immune responses. Elicitins are microbe-associated molecular patterns (MAMPs) specifically produced by oomycetes that activate plant defense. Here, we identified a novel elicitin, PoEli8, from P. oligandrum that exhibits immunity-inducing activity in plants. In vitro-purified PoEli8 induced strong innate immune responses and enhanced resistance to the oomycete pathogen Phytophthora capsici in Solanaceae plants, including Nicotiana benthamiana, tomato, and pepper. Cell death and reactive oxygen species (ROS) accumulation triggered by the PoEli8 protein were dependent on the plant coreceptors receptor-like kinases (RLKs) BAK1 and SOBIR1. Furthermore, REli from N. benthamiana, a cell surface receptor-like protein (RLP) was implicated in the perception of PoEli8 in N. benthamiana. These results indicate the potential value of PoEli8 as a bioactive formula to protect Solanaceae plants against Phytophthora

Novel EIicitin from Pythium oligandrum Confers Disease Resistance against Phytophthora capsici in Solanaceae Plants

The mycoparasite Pythium oligandrum is a nonpathogenic oomycete that can boost plant immune responses. Elicitins are microbe-associated molecular patterns (MAMPs) specifically produced by oomycetes that activate plant defense. Here, we identified a novel elicitin, PoEli8, from P. oligandrum that exhibits immunity-inducing activity in plants. In vitro-purified PoEli8 induced strong innate immune responses and enhanced resistance to the oomycete pathogen Phytophthora capsici in Solanaceae plants, including Nicotiana benthamiana, tomato, and pepper. Cell death and reactive oxygen species (ROS) accumulation triggered by the PoEli8 protein were dependent on the plant coreceptors receptor-like kinases (RLKs) BAK1 and SOBIR1. Furthermore, REli from N. benthamiana, a cell surface receptor-like protein (RLP) was implicated in the perception of PoEli8 in N. benthamiana. These results indicate the potential value of PoEli8 as a bioactive formula to protect Solanaceae plants against Phytophthora

Directional Regulation of Surface Chemistry of Graphene Using Carbon Dots for Sodium-Ion Battery Anodes

In this study, we have fabricated carbon dot/reduced graphene oxide (CDs/rGO) composites using oxygen-functionalized CDs and conductive graphene oxide (GO) by a hydrothermal method and calcination at 250 °C. The CDs can manipulate the surface functional groups of the composites by consuming C–O bonds and introducing CO bonds. As sodium-ion battery anodes, CDs/rGO with a high CO group content exhibits a great reversible capacity of 308 mAh g–1 at 0.05 A g–1, which is up to 1.8 times that of rGO (173 mAh g–1). It retains a capacity of 116 mAh g–1 after 2000 cycles at 2 A g–1. When assembled into a full cell, the activated anode and NVP@C display a higher initial discharge capacity of 291 mAh ganode–1 with an average working voltage of 2.5 V. The good performance of CDs/rGO is mainly due to the synergistic effects of the CDs with abundant Na storage sites and rGO with a conductive network. The improved electrochemical properties are dominated by the capacitive Na storage mechanism. This work implies that the oxygen-functionalized CDs could serve as medium to regulate the surface chemistry of carbon materials

Additional file 2 of ANKRD29, as a new prognostic and immunological biomarker of non–small cell lung cancer, inhibits cell growth and migration by regulating MAPK signaling pathway

Supplementary Material