116 research outputs found

    An investigation of cadmium, hard chromium and their possible replacement coatings for aerospace applications

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    High velocity oxygen fuel (HVOF) thermally sprayedWC/Co/Cr coating is considered as an electroplated hard Cr (EHC) coating replacement and Al-based coatings including electrodeposited Al (EDAl), flame sprayed Al (FSAl) and SermeTel 962 are considered as electrodeposited Cd (EC) coating replacements. This is due to the environmental issues surrounding the continued use of the latter two systems. All these coatings were characterised in terms of composition, morphology, microstructure, porosity and corrosion resistance (electrochemical linear polarisation resistance). Surface analytical techniques used included scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), X-ray photoelectron spectroscopy (XPS) and focused ion beam scanning electron microscopy (FIBSEM). The feasibility of these coatings to replace EHC and EC coatings has also been identified. [Continues.

    The electrodeposition of zinc alloys from ionic liquid electrolytes

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    Electrodeposited zinc alloys have long been recognised as effective barrier and sacrificial coatings for ferrous substrates. The effect of alloying zinc with, in the main, more noble metals, has produced finishes of higher corrosion resistance than simply electrodeposited zinc. In this manner zinc alloys such as zinc-nickel, zinc-cobalt and zinc-iron are routinely electrodeposited on an industrial scale. A further zinc alloy, zinc-manganese, has shown a high level of promise in terms of corrosion resistance but is difficult to electrodeposit from conventional aqueous solutions. The present investigations are centred around examining the formation of zinc alloys, by electrodeposition, from non-aqueous ionic liquids. These electrolytes are essentially molten salts which maintain their liquid state at, or near, to room temperature. Being non-aqueous they are unlikely to promote significant hydrogen evolution from active metal surfaces - a severe problem for the electrodeposition of zinc-manganese alloys from aqueous electrolytes. Electrodeposition conditions for the latter will be discussed in terms of electrolyte types, current density and solution characteristics such as agitation type and temperature. Zinc-manganese alloy electrodeposits will be characterised in terms of their composition and morphology. Finally corrosion resistance data will be presented and this will be compared with other more conventionally deposited zinc alloys

    Effect of heat treatment on zinc whisker growth from electrodeposited coatings

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    The effects of simple heat treatments on electrodeposited zinc coatings formed on mild steel substrates were examined. It was found that over a temperature range of 50-200°C for 1 and 24 h periods zinc whisker growth was evident. The additional effects of electrodeposited coating thickness and subsequent chromium-based passivation processes were also examined in terms of their effect on whisker growth. Individual whisker morphologies were investigated utilising a field emission gun scanning electron microscopy (FEGSEM) and focused ion beam field emission gun scanning electron microscopy (FIB-FEGSEM)

    Data for: Comparison of Clustering Algorithms applied to Fluid Characterization using NMR T1-T2 Maps of Shale

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    Data for: Comparison of Clustering Algorithms applied to Fluid Characterization using NMR T1-T2 Maps of Shal

    Image1_Transcription factors direct epigenetic reprogramming at specific loci in human cancers.JPEG

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    The characterization of epigenetic changes during cancer development and progression led to notable insights regarding the roles of cancer-specific epigenetic reprogramming. Recent studies showed that transcription factors (TFs) are capable to regulate epigenetic reprogramming at specific loci in different cancer types through their DNA-binding activities. However, the causal association of dynamic histone modification change mediated by TFs is still not well elucidated. Here we evaluated the impacts of 636 transcription factor binding activities on histone modification in 24 cancer types. We performed Instrumental Variables analysis by using genetic lesions of TFs as our instrumental proxies, which previously discovered to be associated with histone mark activities. As a result, we showed a total of 6 EpiTFs as strong directors of epigenetic reprogramming of histone modification in cancers, which alters the molecular and clinical phenotypes of cancer. Together our findings highlight a causal mechanism driven by the TFs and genome-wide histone modification, which is relevant to multiple status of oncogenesis.</p

    Image2_Transcription factors direct epigenetic reprogramming at specific loci in human cancers.JPEG

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    The characterization of epigenetic changes during cancer development and progression led to notable insights regarding the roles of cancer-specific epigenetic reprogramming. Recent studies showed that transcription factors (TFs) are capable to regulate epigenetic reprogramming at specific loci in different cancer types through their DNA-binding activities. However, the causal association of dynamic histone modification change mediated by TFs is still not well elucidated. Here we evaluated the impacts of 636 transcription factor binding activities on histone modification in 24 cancer types. We performed Instrumental Variables analysis by using genetic lesions of TFs as our instrumental proxies, which previously discovered to be associated with histone mark activities. As a result, we showed a total of 6 EpiTFs as strong directors of epigenetic reprogramming of histone modification in cancers, which alters the molecular and clinical phenotypes of cancer. Together our findings highlight a causal mechanism driven by the TFs and genome-wide histone modification, which is relevant to multiple status of oncogenesis.</p

    Video_2_Hemifacial spasm caused by unruptured fusiform vertebral aneurysm treated with endovascular coil embolization: a case report.MOV

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    Hemifacial spasm due to fusiform aneurysm of the vertebral artery is extremely rare. The lateral spread response (LSR) is routinely used to monitor hemifacial spasms during microvascular decompression to predict the degree of postoperative remission of hemifacial spasm. We report a case of hemifacial spasm caused by an unruptured fusiform vertebral aneurysm treated with intravascular intervention and monitoring of LSR. A 59-year-old man was admitted to the hospital with a left facial spasm that gradually worsened for 1 year. Preoperative cerebrovascular angiography indicated fusiform aneurysms in the intracranial segment of the left vertebral artery close to the left facial nerve. The patient underwent parent artery occlusion and aneurysm embolization, and LSR was monitored intraoperatively. After intraoperative aneurysm embolization, LSR disappeared immediately. The postoperative review of cerebrovascular angiography indicated that the parent artery and aneurysm were embolized successfully, and the patient's left facial spasm was relieved after surgery. Hemifacial spasm caused by the vertebral artery fusiform aneurysm can be safely and effectively treated by parent artery occlusion and aneurysm embolization. Meanwhile, intraoperative LSR monitoring can be used to predict postoperative efficacy.</p

    sj-docx-1-etp-10.1177_10422587231184079 – Supplemental material for A Recombinant Framework of Technological Information Disclosure and Reward-Based Crowdfunding Performance of Technology Projects

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    Supplemental material, sj-docx-1-etp-10.1177_10422587231184079 for A Recombinant Framework of Technological Information Disclosure and Reward-Based Crowdfunding Performance of Technology Projects by Han Jiang, Yuchen Zhang and Jie Jiao in Entrepreneurship Theory and Practice</p

    Video_1_Hemifacial spasm caused by unruptured fusiform vertebral aneurysm treated with endovascular coil embolization: a case report.MOV

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    Hemifacial spasm due to fusiform aneurysm of the vertebral artery is extremely rare. The lateral spread response (LSR) is routinely used to monitor hemifacial spasms during microvascular decompression to predict the degree of postoperative remission of hemifacial spasm. We report a case of hemifacial spasm caused by an unruptured fusiform vertebral aneurysm treated with intravascular intervention and monitoring of LSR. A 59-year-old man was admitted to the hospital with a left facial spasm that gradually worsened for 1 year. Preoperative cerebrovascular angiography indicated fusiform aneurysms in the intracranial segment of the left vertebral artery close to the left facial nerve. The patient underwent parent artery occlusion and aneurysm embolization, and LSR was monitored intraoperatively. After intraoperative aneurysm embolization, LSR disappeared immediately. The postoperative review of cerebrovascular angiography indicated that the parent artery and aneurysm were embolized successfully, and the patient's left facial spasm was relieved after surgery. Hemifacial spasm caused by the vertebral artery fusiform aneurysm can be safely and effectively treated by parent artery occlusion and aneurysm embolization. Meanwhile, intraoperative LSR monitoring can be used to predict postoperative efficacy.</p
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