1,323 research outputs found
Representation in Wales: an empirical analysis of the policy divisions between voters and candidates
Politics in Wales is often portrayed as being relatively consensual when compared with the rest of the United Kingdom and enjoying healthy levels of trust between voters and elites. Recent events like the decision of Welsh voters to reject the European Union membership against the advice of most of its political establishment, however, are calling to question this perception. Using 2016 Welsh Candidate Study and 2016 Welsh Election Study data, this paper evaluates the extent of policy divisions between voters and candidates in Wales. I find that candidates hold more liberal policy positions and are less likely to think of immigration as the most important policy priority. In addition, they tend to favour a different approach to parliamentary representation, deeming it more acceptable for Assembly Members to discard the views of their voters in favour of their own views or those of their party
The Different Physical Mechanisms that Drive the Star-Formation Histories of Giant and Dwarf Galaxies
We present an analysis of star-formation and nuclear activity in galaxies as
a function of both luminosity and environment in the SDSS DR4 dataset. Using a
sample of 27753 galaxies at 0.00590% complete to Mr=-18.0 we
find that the EW(Ha) distribution is strongly bimodal, allowing galaxies to be
robustly separated into passive and star-forming populations about a value
EW(Ha)=2A. In high-density regions ~70% of galaxies are passive independent of
luminosity. In the rarefied field however, the fraction of passively-evolving
galaxies is a strong function of luminosity, dropping from ~50% for Mr<-21 to
zero by Mr~-18. Indeed for the lowest luminosity range covered (-18<Mr<-16)
none of the ~600 galaxies in the lowest density quartile are passive. The few
passively-evolving dwarf galaxies in field regions appear as satellites to
bright (~L*) galaxies. The fraction of galaxies with optical AGN signatures
decreases steadily from ~50% at Mr~-21 to ~0% by Mr~-18 closely mirroring the
luminosity-dependence of the passive galaxy fraction in low-density
environments. This result reflects the increasing importance of AGN feedback
with galaxy mass for their evolution, such that the star-formation histories of
massive galaxies are primarily determined by their past merger history. In
contrast, the complete absence of passively-evolving dwarf galaxies more than
~2 virial radii from the nearest massive halo (i.e. cluster, group or massive
galaxy) indicates that internal processes, such as merging, AGN feedback or gas
consumption through star-formation, are not responsible for terminating
star-formation in dwarf galaxies. Instead the evolution of dwarf galaxies is
primarily driven by the mass of their host halo, probably through the combined
effects of tidal forces and ram-pressure stripping.Comment: 29 pages, 11 figures. Accepted for publication in MNRA
Competent retrofitting policy and inflation resilience: The cheapest energy is that which you don't use
Given that it is widely acknowledged that the cheapest energy is that which you don't use, we take a tangential approach to issues of energy prices and inflation and focus on energy efficiency policy that reduces demand at source. Our focus is housing retrofitting from an institutional or framework perspective. We briefly set out what retrofitting is (since this is a moving target), and what the need for it is in the UK. We then focus on the Climate Change Committee's current assessment of policy. This brings to the fore the government's minimalist approach to âdeveloping a marketâ. We argue that this approach invokes an individualised market psychology which is both conceptually and practically problematic, given the need for urgency and the current situation of inflation and uncertainty. We conclude by suggesting a fundamental rethink is required
Unpacking Giftedness : Research and Strategies for Promoting Racial and Socioeconomic Equity
Giftedness as a construct continues to be contested in academia, in the classroom and around kitchen tables. It means different things to different communities and, as a result, acquiring the gifted label looks different around the country. Once labeled, student giftedness produces different responses depending on state and district guidelines. A constant among the patchwork of defining, identifying and responding to student giftedness, though, is a serious racial and economic disparity in who is considered gifted and who is not. This report provides key takeaways from research literature on gifted and talented (GT) programs. It is organized according to five questions: 1) What does it mean to be gifted? 2) Who receives gifted services? 3) Why does this matter? 4) What factors contribute to disparities in gifted services? and 5) What strategies help to address disparities in gifted education
Observation and Spectral Measurements of the Crab Nebula with Milagro
The Crab Nebula was detected with the Milagro experiment at a statistical
significance of 17 standard deviations over the lifetime of the experiment. The
experiment was sensitive to approximately 100 GeV - 100 TeV gamma ray air
showers by observing the particle footprint reaching the ground. The fraction
of detectors recording signals from photons at the ground is a suitable proxy
for the energy of the primary particle and has been used to measure the photon
energy spectrum of the Crab Nebula between ~1 and ~100 TeV. The TeV emission is
believed to be caused by inverse-Compton up-scattering scattering of ambient
photons by an energetic electron population. The location of a TeV steepening
or cutoff in the energy spectrum reveals important details about the underlying
electron population. We describe the experiment and the technique for
distinguishing gamma-ray events from the much more-abundant hadronic events. We
describe the calculation of the significance of the excess from the Crab and
how the energy spectrum is fit. The fit is consistent with values measured by
IACTs between 1 and 20 TeV. Fixing the spectral index to values that have been
measured below 1 TeV by IACT experiments (2.4 to 2.6), the fit to the Milagro
data suggests that Crab exhibits a spectral steepening or cutoff between about
20 to 40 TeV.Comment: Submitted to Astrophysical Journa
A Multi-Year Longitudinal Study of Water Quality Parameters in Four Salmon-Bearing and Recreational Streams on Mount Hood, Oregon
Four streamsâClear Fork, Lost Creek, Camp Creek and Still Creekâin northwestern Oregonâs Sandy River Basin were monitored for temperature, dissolved oxygen levels, and fecal bacterial concentrations in a multi-year analysis examining stream health for recreational users and anchor habitat for Pacific Salmon.Temperatures were recorded using micro âT temperature loggers at 15 locations, during 22 July - 5 September 2006, 2 July - 4 September 2007, 20 June - 7 September 2008, 23 June - 9 September 2009, and 2 July â9 September 2010. The Seven-Day Average Maximum water temperature (7-DAM) of 13°C was used as a reference value for the biological limit governing suitable salmonid spawning and egg incubation conditions. The maximum 7-DAM temperatures occurred on different dates and all streams neared or exceeded the 13°C standard at least once each summer. Dissolved oxygen levels were measured at weekly or longer intervals in 2006, 2007, 2008, and 2009. Dissolved oxygen levels fell below the 9.0 ppm standard for Clear Fork on almost half the sampling dates in 2006, 2007, and 2009. Concentrations of the bacterial genus Enterococcus were measured as an indicator of fecal contamination.Samples were collected at 15 sites along the four streams. Weekly samples were collected during a 9 week period from July - September 2007, an 11 week period from June - September 2008, and an 11 week period from June - September 2009. Enterococcus counts exceeded the federal recommended national criterion value of 61 colony forming units (CFU) per 100 mL every year in Camp Creek and occasionally elsewhere, with exceedances trending towards late summer
Public perceptions of climate change as a human health risk : surveys of the United States, Canada and Malta
We used data from nationally representative surveys conducted in the United States, Canada and Malta between 2008 and 2009 to answer three questions: Does the public believe that climate change poses human health risks, and if so, are they seen as current or future risks? Whose health does the public think will be harmed? In what specific ways does the public believe climate change will harm human health? When asked directly about the potential impacts of climate change on health and well-being, a majority of people in all three nations said that it poses significant risks; moreover, about one third of Americans, one half of Canadians, and two-thirds of Maltese said that people are already being harmed. About a third or more of people in the United States and Canada saw themselves (United States, 32%; Canada, 67%), their family (United States, 35%; Canada, 46%), and people in their community (United States, 39%; Canada, 76%) as being vulnerable to at least moderate harm from climate change. About one third of Maltese (31%) said they were most concerned about the risk to themselves and their families. Many Canadians said that the elderly (45%) and children (33%) are at heightened risk of harm, while Americans were more likely to see people in developing countries as being at risk than people in their own nation. When prompted, large numbers of Canadians and Maltese said that climate change can cause respiratory problems (78â91%), heat-related problems (75â84%), cancer (61â90%), and infectious diseases (49â62%). Canadians also named sunburn (79%) and injuries from extreme weather events (73%), and Maltese cited allergies (84%). However, climate change appears to lack salience as a health issue in allthree countries: relatively few people answered open-ended questions in a manner that indicated clear top-of-mind associations between climate change and human health risks. We recommend mounting public health communication initiatives that increase the salience of the human health consequences associated with climate change.peer-reviewe
Gauging NOTCH1 Activation in Cancer Using Immunohistochemistry
Fixed, paraffin-embedded (FPE) tissues are a potentially rich resource for studying the role of NOTCH1 in cancer and other pathologies, but tests that reliably detect activated NOTCH1 (NICD1) in FPE samples have been lacking. Here, we bridge this gap by developing an immunohistochemical (IHC) stain that detects a neoepitope created by the proteolytic cleavage event that activates NOTCH1. Following validation using xenografted cancers and normal tissues with known patterns of NOTCH1 activation, we applied this test to tumors linked to dysregulated Notch signaling by mutational studies. As expected, frequent NICD1 staining was observed in T lymphoblastic leukemia/lymphoma, a tumor in which activating NOTCH1 mutations are common. However, when IHC was used to gauge NOTCH1 activation in other human cancers, several unexpected findings emerged. Among B cell tumors, NICD1 staining was much more frequent in chronic lymphocytic leukemia than would be predicted based on the frequency of NOTCH1 mutations, while mantle cell lymphoma and diffuse large B cell lymphoma showed no evidence of NOTCH1 activation. NICD1 was also detected in 38% of peripheral T cell lymphomas. Of interest, NICD1 staining in chronic lymphocytic leukemia cells and in angioimmunoblastic lymphoma was consistently more pronounced in lymph nodes than in surrounding soft tissues, implicating factors in the nodal microenvironment in NOTCH1 activation in these diseases. Among carcinomas, diffuse strong NICD1 staining was observed in 3.8% of cases of triple negative breast cancer (3 of 78 tumors), but was absent from 151 non-small cell lung carcinomas and 147 ovarian carcinomas. Frequent staining of normal endothelium was also observed; in line with this observation, strong NICD1 staining was also seen in 77% of angiosarcomas. These findings complement insights from genomic sequencing studies and suggest that IHC staining is a valuable experimental tool that may be useful in selection of patients for clinical trials
Decommissioning care: The need for rigorous multifaceted evaluations of decisions to withdraw health services
In this Perspective on the two clinical trials of Terry Haines and colleagues that incrementally removed and reinstated allied healthcare services, Aziz Sheikh discusses the evidence base for the routine provision of such services
The Long-Baseline Neutrino Experiment: Exploring Fundamental Symmetries of the Universe
The preponderance of matter over antimatter in the early Universe, the
dynamics of the supernova bursts that produced the heavy elements necessary for
life and whether protons eventually decay --- these mysteries at the forefront
of particle physics and astrophysics are key to understanding the early
evolution of our Universe, its current state and its eventual fate. The
Long-Baseline Neutrino Experiment (LBNE) represents an extensively developed
plan for a world-class experiment dedicated to addressing these questions. LBNE
is conceived around three central components: (1) a new, high-intensity
neutrino source generated from a megawatt-class proton accelerator at Fermi
National Accelerator Laboratory, (2) a near neutrino detector just downstream
of the source, and (3) a massive liquid argon time-projection chamber deployed
as a far detector deep underground at the Sanford Underground Research
Facility. This facility, located at the site of the former Homestake Mine in
Lead, South Dakota, is approximately 1,300 km from the neutrino source at
Fermilab -- a distance (baseline) that delivers optimal sensitivity to neutrino
charge-parity symmetry violation and mass ordering effects. This ambitious yet
cost-effective design incorporates scalability and flexibility and can
accommodate a variety of upgrades and contributions. With its exceptional
combination of experimental configuration, technical capabilities, and
potential for transformative discoveries, LBNE promises to be a vital facility
for the field of particle physics worldwide, providing physicists from around
the globe with opportunities to collaborate in a twenty to thirty year program
of exciting science. In this document we provide a comprehensive overview of
LBNE's scientific objectives, its place in the landscape of neutrino physics
worldwide, the technologies it will incorporate and the capabilities it will
possess.Comment: Major update of previous version. This is the reference document for
LBNE science program and current status. Chapters 1, 3, and 9 provide a
comprehensive overview of LBNE's scientific objectives, its place in the
landscape of neutrino physics worldwide, the technologies it will incorporate
and the capabilities it will possess. 288 pages, 116 figure
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