ANALISA DAN PERANCANGAN SISTEM INFORMASI PERENCANAAN PREVENTIVE MAINTENANCE PADA PT. KEONG NUSANTARA ABADI INDONESIA

ANALISA DAN PERANCANGAN SISTEM INFORMASI PERENCANAAN PREVENTIVE MAINTENANCE PADA PT. KEONG NUSANTARA ABADI INDONESIA - preventive maintenance, breakdown, age replacement, MTTR, MTTF, interval penggantian, reliability, sistem informasi, dan Object Oriented Analysis and Desig

INTERAKSI SOSIAL REMAJA ANTAR ETNIK DI DESA SALATIGA KECAMATAN MANDOR KABUPATEN LANDAK

Tujuan penelitian ini adalah untuk mengetahui interaksi yang terjadi pada remaja antar etnik di Desa Salatiga Kecamatan Mandor Kabupaten Landak. Metode yang digunakan dalam penelitian ini menggunakan metode kualitatif dengan teknik pengumpulan data berupa wawancara, observasi dan dokumentasi. Teknik analisis data menggunakan analisis data interaktif yang terdiri dari reduksi data, penyajian data dan penarikan kesimpulan. Teknik keabsahan data menggunakan teknik triangulasi sumber dan triangulasi teknik. Hasil penelitian menunjukkan bahwa bentuk interaksi sosial remaja antar etnik di Desa Salatiga berupa kerja sama, toleransi dan asimilasi. Kerjasama yang terjadi berupa kegiatan bersama seperti berkumpul bersama, mengobrol, membuat rujak bersama, membuat kue, dan bermain bola bersama. Toleransi yang terjadi berupa tidak adanya perselisihan di antara remaja antar etnik tersebut dengan terbentuknya rasa saling sepakat untuk tidak melakukan perselisihan dengan etnik lain. Asimilasi berupa upaya mengurangi perbedaan dengan penggunaan bahasa daerah dan bahasa Indonesia

Analyzing Molecular Traits of H9N2 Avian Influenza Virus Isolated from a Same Poultry Farm in West Java Province, Indonesia, in 2017 and 2023 [version 2; peer review: 1 approved, 2 approved with reservations]

Background Indonesia is one of the countries that is endemic to avian influenza virus subtype H9N2. This study aims to compare the molecular characteristics of avian influenza virus (AIV) subtype H9N2 from West Java. Methods Specific pathogen-free (SPF) embryonated chicken eggs were used to inoculate samples. RNA extraction and RT–qPCR confirmed the presence of H9 and N2 genes in the samples. RT–PCR was employed to amplify the H9N2-positive sample. Nucleotide sequences were obtained through Sanger sequencing and analyzed using MEGA 7. Homology comparison and phylogenetic tree analysis, utilizing the neighbor-joining tree method, assessed the recent isolate’s similarity to reference isolates from GenBank. Molecular docking analysis was performed on the HA1 protein of the recent isolate and the A/Layer/Indonesia/WestJava-04/2017 isolate, comparing their interactions with the sialic acids Neu5Ac2-3Gal and Neu5Ac2-6Gal. Results RT–qPCR confirmed the isolate samples as AIV subtype H9N2. The recent virus exhibited 11 amino acid residue differences compared to the A/Layer/Indonesia/WestJava-04/2017 isolate. Phylogenetically, the recent virus remains within the h9.4.2.5 subclade. Notably, at antigenic site II, the recent isolate featured an amino acid N at position 183, unlike A/Layer/Indonesia/WestJava-04/2017. Molecular docking analysis revealed a preference of HA1 from the 2017 virus for Neu5Ac2-3Gal, while the 2023 virus displayed a tendency to predominantly bind with Neu5Ac2-6Gal. Conclusion In summary, the recent isolate displayed multiple mutations and a strong affinity for Neu5Ac2-6Gal, commonly found in mammals

Menumbuhkan Sikap Multikulturalisme Remaja sebagai Bentuk Pendidikan IPS oleh Orang Tua

Penelitian ini bertujuan untuk mengetahui tentang pandangan orang tua terhadap multikulturalisme, peran orang tua menumbuhkan sikap multikulturalisme kalangan remaja, sikap multikulturalisme di kalangan remaja, dan relevansi antara peran orang tua menumbuhkan sikap multikulturalisme kalangan remaja dengan pelaksanaan pendidikan IPS di Indonesia. Metode penelitian yang digunakan adalah metode kualitatif yang mendasarkan pada teori interaksionisme simbolik milik Hebert Blumer. Instrumen pengumpulan data dilakukan melalui observasi nonpartisipasi, wawancara mendalam dan dokumentasi tertulis atau foto.Teknik analisis data menggunakan tahapan proses analisis interaktif dalam penelitian kualitatif milik miles dan Huberman. Hasil penelitian menunjukkan para orang tua cenderung memandang multikulturalisme sebagai sesuatu yang dibutuhkan kalangan remaja dalam proses sosialnya. Peran orang tua menumbuhkan sikap mulrikulturalsime berupa pemberian keleluasaan dan dukungan dalam praktik pertemanan, serta keteladanan orang tua tentang sikap multikulturalisme dalam kehidupan sehari-hari. Sikap multikulturalisme kalangan remaja berupa sikap toleransi, tolong-menolong, menjunjung tinggi prisnsip kesetaraan dan mengutamakan dialog saat terjadi perselisihan. Terdapat relevansi antara peran orang tua dan  sikap multikulturalisme dengan tujuan pelaksanaan pendidikan IPS di Indonesia.</jats:p

Burden and attitude to resistant and refractory migraine: a survey from the European Headache Federation with the endorsement of the European Migraine & Headache Alliance

Background: New treatments are currently offering new opportunities and challenges in clinical management and research in the migraine field. There is the need of homogenous criteria to identify candidates for treatment escalation as well as of reliable criteria to identify refractoriness to treatment. To overcome those issues, the European Headache Federation (EHF) issued a Consensus document to propose criteria to approach difficult-to-treat migraine patients in a standardized way. The Consensus proposed well-defined criteria for resistant migraine (i.e., patients who do not respond to some treatment but who have residual therapeutic opportunities) and refractory migraine (i.e., patients who still have debilitating migraine despite maximal treatment efforts). The aim of this study was to better understand the perceived impact of resistant and refractory migraine and the attitude of physicians involved in migraine care toward those conditions. Methods: We conducted a web-questionnaire-based cross-sectional international study involving physicians with interest in headache care. Results: There were 277 questionnaires available for analysis. A relevant proportion of participants reported that patients with resistant and refractory migraine were frequently seen in their clinical practice (49.5% for resistant and 28.9% for refractory migraine); percentages were higher when considering only those working in specialized headache centers (75% and 46% respectively). However, many physicians reported low or moderate confidence in managing resistant (8.1% and 43.3%, respectively) and refractory (20.7% and 48.4%, respectively) migraine patients; confidence in treating resistant and refractory migraine patients was different according to the level of care and to the number of patients visited per week. Patients with resistant and refractory migraine were infrequently referred to more specialized centers (12% and 19%, respectively); also in this case, figures were different according to the level of care. Conclusions: This report highlights the clinical relevance of difficult-to-treat migraine and the presence of unmet needs in this field. There is the need of more evidence regarding the management of those patients and clear guidance referring to the organization of care and available opportunities