221 research outputs found

    The nature of the amenorrhea of lactation in humans.

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    On the standing wave mode of giant pulsations

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    Both odd-mode and even-mode standing wave structures have been proposed for giant pulsations. Unless a conclusion is drawn on the field-aligned mode structure, little progress can be made in understanding the excitation mechanism of giant pulsations. In order to determine the standing wave mode, we have made a systematic survey of magnetic field data from the AMPTE CCE spacecraft and from ground stations located near the geomagnetic foot point of CCE. We selected time intervals when CCE was close to the magnetic equator and also magnetically close to Syowa and stations in Iceland, and when either transverse or compressional Pc 4 waves were observed at CCE. Magnetograms from the ground stations were then examined to determine if there was a giant pulsation in a given time interval. One giant pulsation was associated with a compressional wave, while no giant pulsation was observed in association with transverse wave events. The CCE magnetic field record for the giant pulsation exhibited a remarkable similarity to a giant pulsation observed from the ATS 6 geostationary satellite near the magnetic equator (Hillebrand et al., 1982). In agreement with Hillebrand et al., we conclude that the compressional nature of the giant pulsation is due to an odd-mode standing wave structure. This conclusion places a strong constraint on the generation mechanism of giant pulsations. In particular, if giant pulsations are excited through the drift bounce resonance of ions with standing Alfvén waves, ω - mωd = ±Nωb, where ω is the wave frequency, m is the azimuthal wave number, ωd is the ion drift frequency,N is an integer, and ωb is the ion bounce frequency, then the resonance must occur at an even N

    Global features of the disturbance winds during storm time deduced from CHAMP observations

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    A wind-driven disturbance dynamo has been postulated many decades ago. But due to the sparseness of thermospheric wind measurements, details of the phenomena could not be investigated. In this study we use the CHAMP zonal wind observations from 2001 to 2005 to investigate the global features of the disturbance winds during magnetically disturbed periods. The disturbance zonal wind is mainly westward, which increases with magnetic activity and latitude. At subauroral region, the westward zonal wind is strongly enhanced in the magnetic local time (MLT) sector from afternoon to midnight, which we relate to the plasma drift within the subauroral polarization streams. At middle and low latitudes, the disturbance zonal wind is largely independent of season. Peak values of the disturbance zonal wind occur at different MLTs for different latitudes. That is around 1800MLT at subauroal region, with average values of about 200m/s; around 2300 MLT at middle latitudes, with average values of about 80m/s; and around 0300MLT at low latitudes, with average values up to 50m/s. The shift of the peak values of the westward disturbance zonal wind in local time at different latitudes could be considered as a response of the disturbance wind when it propagates from high to low latitudes. Further by applying for the first time a superposed epoch analysis, we show that the disturbance zonal wind responds with a delay to the sudden changes of solar wind input, which is different for the various latitudinal ranges. The propagation time of disturbance wind from the auroral region to the equator is about 3-4h. This is consistent with the speed of traveling atmospheric disturbances. Based on CHAMP observations, we try to illustrate the whole chain of processes from the solar wind driving to the ionospheric effects at lower latitudes. ©2015. American Geophysical Union. All Rights Reserved

    Recognition of human activity through hierarchical stochastic learning

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    The chance of freezing – a conceptional study to parameterize temperature-dependent freezing by including randomness of ice-nucleating particle concentrations

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    Ice-nucleating particle concentrations (INPCs) can spread over several orders of magnitude at any given temperature. However, this variability is rarely accounted for in heterogeneous ice-nucleation parameterizations. In this paper, we present an approach to incorporate the random variation in the INPC into the parameterization of immersion freezing and analyze this novel concept with various sensitivity tests. In the new scheme, the INPC is drawn from a relative frequency distribution of cumulative INPCs. At each temperature, this distribution describing the INPCs is expressed as a lognormal frequency distribution. The new parameterization scheme does not require aerosol information from the driving model to represent the heterogeneity of INPCs. The scheme's performance is tested in a large-eddy simulation of a relatively warm Arctic mixed-phase stratocumulus. We find that it leads to reasonable ice masses in the cloud, especially when compared to immersion freezing schemes that yield one fixed INPC per temperature and lead to almost no ice production in the simulated cloud. The scheme is sensitive to the median of the frequency distribution and highly sensitive to the standard deviation of the distribution, as well as to the frequency of drawing a new INPC and the resolution of the model. Generally, a higher probability of drawing large INPCs leads to substantially more ice in the simulated cloud. We expose inherent challenges to introducing such a parameterization and explore possible solutions and potential developments.</p

    The Pleistocene cinder cones surrounding Volcán Colima, Mexico re-visited: eruption ages and volumes, oxidation states, and sulfur content

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    Located at the volcanic front in the western Mexican arc, in the Colima Rift, is the active Volcán Colima, which lies on the southern end of the massive (∼450 km 3 ) Colima-Nevado volcanic complex. Along the margins of this andesitic volcanic complex, is a group of 11 scoria cones and associated lavas, which have been dated by the 40 Ar/ 39 Ar method. Nine scoria cones erupted ∼1.3 km 3 of alkaline magma (basanite, leucite-basanite, minette) between 450 and 60 ka, with >99% between 240 and 60 ka. Two additional cones (both the oldest and calc-alkaline) erupted <0.003 km 3 of basalt (0.5 Ma) and <0.003 km 3 of basaltic andesite (1.2 Ma), respectively. Cone and lava volumes were estimated with the aid of digital elevation models (DEMs). The eruption rate for these scoria cones and their associated lavas over the last 1.2 Myr is ∼1.2 km 3 /Myr, which is more than 400 times smaller than that from the andesitic Colima-Nevado edifice. In addition to these alkaline Colima cones, two other potassic basalts erupted at the volcanic front, but ∼200 km to the ESE (near the historically active Volcán Jorullo), and were dated at 1.06 and 0.10 Ma. These potassic suites reflect the tendency in the west-central Mexican arc for magmas close to the volcanic front to be enriched in K 2 O relative to those farther from the trench.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/47809/1/445_2005_Article_15.pd

    Geotail Measurements Compared with the Motions of High-Latitude Auroral Boundaries during Two Substorms

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    Geotail plasma and field measurements at -95 R(sub E) are compared with extensive ground-based, near-Earth, and geosynchronous measurements to study relationships between auroral activity and magnetotail dynamics during the expansion phases of two substorms. The studied intervals are representative of intermittent, moderate activity. The behavior of the aurora and the observed effects at Geotail for both events are harmonized by the concept of the activation of near-Earth X lines (NEXL) after substorm onsets, with subsequent discharges of one or more plasmoids down the magnetotail. The plasmoids must be viewed as three-dimensional structures which are spatially limited in the dawn-dusk direction. Also, reconnection at the NEXL must proceed at variable rates on closed magnetic field lines for significant times before beginning to reconnect lobe flux. This implies that the plasma sheet in the near-Earth magnetotail is relatively thick in comparison with an embedded current sheet and that both the NEXL and distant X line can be active simultaneously. Until reconnection at the NEXL engages lobe flux, the distant X line maintains control of the poleward auroral boundary. If the NEXL remains active after reaching the lobe, the auroral boundary can move poleward explosively. The dynamics of high-latitude aurora in the midnight region thus provides a means for monitoring these processes and indicating when significant lobe flux reconnects at the NEXL

    Inhibition of cholesterol recycling impairs cellular PrPSc propagation

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    The infectious agent in prion diseases consists of an aberrantly folded isoform of the cellular prion protein (PrPc), termed PrPSc, which accumulates in brains of affected individuals. Studies on prion-infected cultured cells indicate that cellular cholesterol homeostasis influences PrPSc propagation. Here, we demonstrate that the cellular PrPSc content decreases upon accumulation of cholesterol in late endosomes, as induced by NPC-1 knock-down or treatment with U18666A. PrPc trafficking, lipid raft association, and membrane turnover are not significantly altered by such treatments. Cellular PrPSc formation is not impaired, suggesting that PrPSc degradation is increased by intracellular cholesterol accumulation. Interestingly, PrPSc propagation in U18666A-treated cells was partially restored by overexpression of rab 9, which causes redistribution of cholesterol and possibly of PrPSc to the trans-Golgi network. Surprisingly, rab 9 overexpression itself reduced cellular PrPSc content, indicating that PrPSc production is highly sensitive to alterations in dynamics of vesicle trafficking
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