508 research outputs found

    Appreciating the Performance of Neuroscience Mining in NeuroIS research: A Case Study on Consumer\u27s Product Perceptions in the Two UI Modes—Dark UI vs. Light UI

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    The goal of the current study was to provide information on the potential of neuroscience mining (NSM) for comprehending NeuroIS paradigms. NSM is an interdisciplinary field that combines neuroscience and business mining, which is the application of big data analytics, computational social science, and other fields to business problems. Therefore, NSM makes it possible to apply predictive models to NeuroIS datasets, such as machine learning and deep learning, to find intricate patterns that are hidden by conventional regression-based analysis. We predicted 28 individual EEG power spectra separated brainwave data using a Random Forest (RF) model. Next, we used NSM to precisely predict how consumers would perceive a product online, depending on whether a light or dark user interface (UI) mode was being used. The model was then used to extract more precise results that could not be obtained using more conventional linear-based analytical models using sensitivity analysis. The benefits of using NSM in NeuroIS research are as follows: (1) it can relieve the burden of the three-horned dilemma described by Runkel and McGrath; (2) it can enable more temporal data to be directly analyzed on the target variables; and (3) sensitivity analysis can be performed on a condition/individual basis, strengthening the rigor of findings by reducing sample bias that can be lost in grand averaging of data when analyzed with methods like GLM

    Appreciating the Performance of Neuroscience Mining in NeuroIS research: A Case Study on Consumer's Product Perceptions in the Two UI Modes—Dark UI vs. Light UI

    Get PDF
    The goal of the current study was to provide information on the potential of neuroscience mining (NSM) for comprehending NeuroIS paradigms. NSM is an interdisciplinary field that combines neuroscience and business mining, which is the application of big data analytics, computational social science, and other fields to business problems. Therefore, NSM makes it possible to apply predictive models to NeuroIS datasets, such as machine learning and deep learning, to find intricate patterns that are hidden by conventional regression-based analysis. We predicted 28 individual EEG power spectra separated brainwave data using a Random Forest (RF) model. Next, we used NSM to precisely predict how consumers would perceive a product online, depending on whether a light or dark user interface (UI) mode was being used. The model was then used to extract more precise results that could not be obtained using more conventional linear-based analytical models using sensitivity analysis. The benefits of using NSM in NeuroIS research are as follows: (1) it can relieve the burden of the three-horned dilemma described by Runkel and McGrath; (2) it can enable more temporal data to be directly analyzed on the target variables; and (3) sensitivity analysis can be performed on a condition/individual basis, strengthening the rigor of findings by reducing sample bias that can be lost in grand averaging of data when analyzed with methods like GLM

    Enhancement on Radon Adsorption Property of GAC using Nano-size Carbon Colloids

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    Granular activated carbon (GAC) is well-known as an efficient adsorbent against a number of gaseous pollutants. Radon is one of those pollutants, and radon has been classified as the second leading cause of lung cancer in USA. This study was to enhance the radon removal efficiency with applying nano-technology. Nano-size carbon colloids (NCC) was produced through electrolysis which is simple and cheap. NCC was used for impregnation with activated carbon. Surface areas of both NCC-treated and non-treated activated carbon did not show a significant difference. However, the results of radon removal efficiency show that impregnated carbon with NCC could capture about 1.3 ~ 2 times of more radon gas compared to non-treated activated carbon. It is assumed that nano-size carbon colloids might have filled up meso-pores, and meso-pores turned into micro-pores eventually. Because meso-pores initially accounted for large portion of whole pores, more radon could be captured to NCC-impregnated activated carbon. Keywords: Radon, Nano-Size Carbon Collid, Activated Carbo

    STRAIN BEHAVIOUR OF ULTRA-HIGH-STRENGTH CONCRETE UNDER THE ELEVATED TEMPERATURE AND 0.25FCK LOADING

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    The high-temperature creep of Ultra-High-Strength Concrete (UHSC) has been investigated in this study. The purpose of this study is to evaluated total strain and high-temperature creep at elevated temperatures under loading condition of UHSC. To evaluate the strain behaviour of UHSC at elevated temperatures, ϕ100 mm × 200 mm cylindrical specimens of UHSC with compressive strengths of 80, 130 and 180 MPa concrete were heated to 700 °C at a rate of 1 °C/min. The total strain and high-temperature-creep were measured under the loading condition of 0.25 of the compressive strength at room temperature. As results, Total strain of UHSC increased showing shrinkage with increasing compressive strength. The high-temperature creep of UHSC increased with the temperature and higher level of compressive strength showed bigger high-temperature creep

    Current Trends for Treating Lateral Epicondylitis

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    Lateral epicondylitis, also known as ‘tennis elbow’, is a degenerative rather than inflammatory tendinopathy, causing chronic recalcitrant pain in elbow joints. Although most patients with lateral epicondylitis resolve spontaneously or with standard conservative management, few refractory lateral epicondylitis are candidates for alternative non-operative and operative modalities. Other than standard conservative treatments including rest, analgesics, non-steroidal anti-inflammatory medications, orthosis and physical therapies, nonoperative treatments encompass interventional therapies include different types of injections, such as corticosteroid, lidocaine, autologous blood, platelet-rich plasma, and botulinum toxin, which are available for both short-term and long-term outcomes in pain resolution and functional improvement. In addition, newly emerging biologic enhancement products such as bone marrow aspirate concentrate and autologous tenocyte injectates are also under clinical use and investigations. Despite all non-operative therapeutic trials, persistent debilitating pain in patients with lateral epicondylitis for more than 6 months are candidates for surgical treatment, which include open, percutaneous, and arthroscopic approaches. This review addresses the current updates on emerging non-operative injection therapies as well as arthroscopic intervention in lateral epicondylitis

    Homeobox gene Dlx-2 is implicated in metabolic stress-induced necrosis

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    <p>Abstract</p> <p>Background</p> <p>In contrast to tumor-suppressive apoptosis and autophagic cell death, necrosis promotes tumor progression by releasing the pro-inflammatory and tumor-promoting cytokine high mobility group box 1 (HMGB1), and its presence in tumor patients is associated with poor prognosis. Thus, necrosis has important clinical implications in tumor development; however, its molecular mechanism remains poorly understood.</p> <p>Results</p> <p>In the present study, we show that Distal-less 2 (Dlx-2), a homeobox gene of the Dlx family that is involved in embryonic development, is induced in cancer cell lines dependently of reactive oxygen species (ROS) in response to glucose deprivation (GD), one of the metabolic stresses occurring in solid tumors. Increased Dlx-2 expression was also detected in the inner regions, which experience metabolic stress, of human tumors and of a multicellular tumor spheroid, an <it>in vitro </it>model of solid tumors. Dlx-2 short hairpin RNA (shRNA) inhibited metabolic stress-induced increase in propidium iodide-positive cell population and HMGB1 and lactate dehydrogenase (LDH) release, indicating the important role(s) of Dlx-2 in metabolic stress-induced necrosis. Dlx-2 shRNA appeared to exert its anti-necrotic effects by preventing metabolic stress-induced increases in mitochondrial ROS, which are responsible for triggering necrosis.</p> <p>Conclusions</p> <p>These results suggest that Dlx-2 may be involved in tumor progression via the regulation of metabolic stress-induced necrosis.</p
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