第665回 千葉医学会例会・第18回 佐藤外科例会 6.

Estimates of Diptychus maculatus divergence times obtained with BEASTv1.8.0. (DOCX 86 kb

Additional file 4: Table S3. of Phylogeography of Diptychus maculatus (Cyprinidae) endemic to the northern margin of the QTP and Tien Shan region

Mean divergence values between clades for Diptychus maculatus. (DOCX 16 kb

Additional file 3: Table S2. of Phylogeography of Diptychus maculatus (Cyprinidae) endemic to the northern margin of the QTP and Tien Shan region

The F ST values among the populations of Diptychus maculatus based on the combined mtDNA data. (DOCX 21 kb

Color-Tunable Emission and Energy Transfer in Ca₃Gd₇(PO₄)(SiO₄)₅O₂: Ce³⁺/Tb³⁺/Mn²⁺ Phosphors

Ce³⁺-, Tb³⁺-, and Mn²⁺-activated Ca₃Gd₇(PO₄)­(SiO₄)₅O₂ (CGPS) silicate–phosphate oxyapatite phosphors have been prepared via conventional solid-state reaction processes. The Ce³⁺ emission at different lattice sites has been identified and discussed. The dual energy transfer of Ce³⁺ → Tb³⁺ and Ce³⁺ → Mn²⁺ has been investigated. The energy transfer from Ce³⁺ to Mn²⁺ in CGPS phosphors has been demonstrated to be a resonant type via a dipole–quadrupole mechanism, and the critical distances (<i>R</i>_C) for Ce³⁺ to Mn²⁺ calculated by the concentration quenching and spectral overlap methods are 9.71 and 9.15 Å, respectively. A color-tunable emission in CGPS phosphors can be realized by Ce³⁺ → Tb³⁺ or Ce³⁺ → Mn²⁺ energy transfer. CGPS:0.05Ce³⁺/ 0.15Tb³⁺ shows the optimum green emission. Meanwhile, white cathodoluminescence (CL) has been realized in a single-phased Ca₃Gd₇(PO₄)­(SiO₄)₅O₂ host by codoping with Ce³⁺ and Mn²⁺ with CIE (0.322, 0.326). Furthermore, the CL properties of CGPS:Ce³⁺/Tb³⁺/Mn²⁺ phosphors, including the dependence of the CL intensity on the accelerating voltage and filament current, the decay behavior of the CL intensity under electron bombardment, and the stability of the CIE chromaticity coordinates, have been investigated in detail. Because of the good CL properties and good CIE chromaticity coordinates, the as-prepared phosphors have potential application in field emission display devices

Light-Induced Charge Transfer to Achieve Deep-Red Emission in SrSc₂O₄:Bi toward Multiple Optical Applications

Bismuth (Bi) is used for luminescent materials due to its unique optical performance, but deep-red light from Bi-doped materials is rarely reported. In particular, establishing a design principle for Bi-doped red materials is considered to be a significant challenge. Herein, using a deep-red SrSc2O4:Bi material featuring Bi–Bi pair emission, light-induced charge-transfer from BiSc3+–BiSr3+ to BiSc4+–BiSr2+ enables the realization of Bi2+2P3/2(1) → 2S1/2 deep-red emission. Intriguingly, SrSc2O4:Bi displays an excellent zero-thermal-quenching performance from 298 to 423 K, with a peak intensity that retains 98% of the intensity at 298 K and an integrated intensity at 423 K that even reaches 110% of the initial intensity. The intriguing spectroscopic characteristics of SrSc2O4:Bi make it a promising candidate in the agricultural field, night-vision security, and the medical treatment area. This work advances the understanding of red luminescence in Bi-activated luminescent materials and thus can initiate more exploitation of red materials for emerging applications

Color Tuning Luminescence of Ce³⁺/Mn²⁺/Tb³⁺-Triactivated Mg₂Y₈(SiO₄)₆O₂ via Energy Transfer: Potential Single-Phase White-Light-Emitting Phosphors

Ce³⁺, Mn²⁺, and Tb³⁺-activated Mg₂Y₈(SiO₄)₆O₂ (MYS) oxyapatite phosphors have been prepared via solid state reaction process. The Ce³⁺ emission at different lattice sites in MYS host has been identified and discussed. Under UV excitation, there exist dual energy transfers (ET), that is, Ce³⁺ → Mn²⁺ and Ce³⁺ → Tb³⁺ in the MYS: Ce³⁺/Mn²⁺/Tb³⁺ system. The energy transfer from Ce³⁺ to Mn²⁺ in MYS: Ce³⁺/Mn²⁺ phosphors has been demonstrated to be a resonant type via a dipole–quadrupole mechanism, and the critical distance (<i>R</i>_C) calculated by quenching concentration method and spectral overlap method are 10.5 and 9.7 Å, respectively. The emitting colors of MYS: Ce³⁺/Mn²⁺/Tb³⁺ samples can be adjusted from blue to orange-red via ET of Ce³⁺ → Mn²⁺ and from blue to green via ET of Ce³⁺ → Tb³⁺, respectively. More importantly, a wide-range-tunable white light emission with high quantum yields (37–47%) were obtained by precise control of the contents of Ce³⁺, Mn²⁺, and Tb³⁺ ions. On the other hand, the CL properties of MYS: Ce³⁺/Mn²⁺/Tb³⁺ phosphors have been investigated in detail. The results indicate that the as-prepared MYS: Ce³⁺/Mn²⁺/Tb³⁺ phosphors have good CL intensity and CIE coordinate stability with a color-tunable emission crossing the whole visible light region under low-voltage electron beam excitation. In conclusion, the white light with varied hues has been obtained in Ce³⁺, Mn²⁺ and Tb³⁺-activated MYS phosphors by utilizing the principle of energy transfer and properly designed activator contents as well as the select of excitation wavelength under UV and low-voltage electron beam excitation

CD97 small isoform supports metastatic spread of orthotopically implanted gastric cancer.

<p>(A) The size of subcutaneous formed tumor masses of CD97/EGF1,2,5 kd group was significantly smaller. (B) Primary tumor weight of orthotopically transplanted gastric cancer in CD97/EGF1,2,5 kd group was significantly lighter (*p<0.01). (C) The metastatic tumor cells within regional lymph nodes were counted by C4.4A staining and FACS (*p<0.01). (D) Immunohistochemistry: CD44, VEGFR, CD31 and CD97 expression in early metastatic regional lymph nodes of CD97/EGF1,2,5 kd group were strongly down regulated.</p

Generation of transfectants with stable knockdown of CD97 small isoform.

<p>(A) CD97 expression on gastric carcinoma cell lines SGC-7901, AGS, BGC-823 and MGC-801. (B) Expression of CD97 isoforms in SGCwt, SGC-NS and CD97/EGF1,2,5 knockdown groups. Semi-quantitative RT-PCR analysis, performed with the Bio 1D software, revealed differentially expressed (C) CD97 small and (D) big isoforms of the four cell lines, and significantly decreased levels of (E) CD97 small isoforms in CD97/EGF1,2,5 knockdown group as compared with corresponding controls (*p<0.01). (F) The ∼85 kDa CD97 protein was detected by Western blot analysis in total cellular extracts of SGCwt cells, SGC-NS and CD97/EGF1,2,5 knockdown transfectants.</p

RNAi candidate target sequences for CD97 isoform 3.

<p>RNAi candidate target sequences for CD97 isoform 3.</p

16S rRNA-Hap

Specimens were collected from the Ili River, Kaidu River, and Junggar Basin in Xinjiang，China. DNA sequences were edited using the program DNASTAR 5.0 (DNASTAR Inc.), and were aligned using CLUSTALW as implemented in MEGA 5.0