2,668 research outputs found

    Measurements of Higgs boson production and properties in the WW decay channel with both W's decaying into electrons or muons plus neutrino using the CMS detector

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    AbstractIn the data collected so far at the LHC collider, the CMS experiment measured a strong evidence for a new resonance at an invariant mass of about 125 GeV. The analysis is outlined in its most important aspects, as well as the main results obtained. In fact, this final state allows for a very precise determination of the signal cross-section, and for the investigation of the tensor structure of the resonance decay. Results show that the behaviour of the new particle is compatible with the expectations for a Standard Model Higgs boson

    SLN melanoma micrometastasis predictivity of nodal status: a long term retrospective study

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    BACKGROUND: Completion lymph node dissection (CLND) is the gold standard treatment for patients with a positive sentinel lymph node (SLN) biopsy. Considering the morbidity associated with CLND it is important to identify histological features of the primary tumor and/or of SLN metastasis that could help to spare from CLND a subset of patients who have a very low risk of non-SLN metastasis. The objective of this study is to identify patients with a very low risk to develop non-SLNs recurrences and to limit unnecessary CLND. METHODS: A retrospective long-term study of 80 melanoma patients with positive SLN, undergone CLND, was assessed to define the risk of additional metastasis in the regional nodal basin, on the basis of intranodal distribution of metastatic cells, using the micro-morphometric analysis (Starz classification). RESULTS: This study demonstrates that among the demographic and pathologic features of primary melanoma and of SLN only the Starz classification shows prognostic significance for non-SLN status (p<0.0001). This parameter was also significantly associated with disease-free survival rate (p<0.0013). CONCLUSION: The Starz classification can help to identify, among SLN positive patients, those who can have a real benefit from CLND. From the clinical point of view this easy and reliable method could lead to a significant reduction of unnecessary CLND in association with a substantial decrease in morbidity. The study results indicate that most of S1 subgroup patients might be safely spared from completion lymphatic node dissection. Furthermore, our experience demonstrated that Starz classification of SLN is a safe predictive index for patient stratification and treatment planning

    Same Sign WW Scattering Process as a Probe of Higgs Boson in pp Collision at s\sqrt{s} = 10 TeV

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    WW scattering is an important process to study electroweak symmetry breaking in the Standard Model at the LHC, in which the Higgs mechanism or other new physics processes must intervene to preserve the unitarity of the process below 1 TeV. This channel is expected to be one of the most sensitive to determine whether the Higgs boson exists. In this paper, the final state with two same sign Ws is studied, with a simulated sample corresponding to the integrated luminosity of 60 fb1^{-1} in pp collision at s=\sqrt{s}=10 TeV. Two observables, the invariant mass of μμ\mu\mu from W decays and the azimuthal angle difference between the two μ\mus, are utilized to distinguish the Higgs boson existence scenario from the Higgs boson absence scenario. A good signal significance for the two cases can be achieved. If we define the separation power of the analysis as the distance, in the log-likelihood plane, of pseudo-experiments outcomes in the two cases, with the total statistics expected from the ATLAS and CMS experiments at the nominal centre-of-mass energy of 14 TeV, the separation power will be at the level of 4 σ\sigma.Comment: 5 pages, 4 figures, 3 table

    Effects of zoledronic acid and dexamethasone on early phases of socket healing after tooth extraction in rats : a preliminary macroscopic and microscopic quantitative study

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    The exact pathogenesis of medication-related osteonecrosis of the jaw (MRONJ) is still unknown. The aim of this paper was to investigate the effects of zoledronic acid and dexamethasone on the early phases of socket healing in rats subjected to tooth extractions. Thirty male Sprague-Dawley rats were divided into 2 groups: pharmacologically treated group (T, n=20) and non-pharmacologically treated group (C, n=10). T group rats received 0.1 mg/Kg of zoledronic acid (ZOL) and 1 mg/Kg of dexamethasone (DEX) three times a week for 10 consecutive weeks. C group rats were infused with vehicle. After 9 weeks from the first infusion, first maxillary molars were extracted in each of the rats. Quantitative macroscopic and microscopic analysis was performed to evaluate socket healing 8 days after extraction. Pharmacologically treated rats showed significant inhibition of bone remodeling. Connective tissue/alveolar bone ratio, osteoclast number and woven bone deposition were significantly reduced in group T compared to group C. Conversely, the proportion of necrotic bone was higher in group T compared to group C (0.8% and 0.3%, respectively. P=0.031). ZOL plus DEX do not cause gross effects on socket healing at a macroscopic level. Our findings confirmed that exposure to ZOL plus DEX impairs alveolar wound repair. Inhibition of osteoclastic resorption of socket walls after tooth extraction and the inability to dispose of the necrotic bone may be considered the initial steps of MRONJ onset

    Probing New Physics via pp-> W+W- -> lvjj at the CERN LHC

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    TeV scale new Physics, e.g., Large Extra Dimensions or Models with anomalous triple vector boson couplings, can lead to excesses in various kinematic regions on the semi-leptonic productions of pp -> WW -> lvjj at the CERN LHC, which, although suffers from large QCD background compared with the pure leptonic channel, can benefit from larger production rates and the reconstructable 4-body mass Mlvjj. We study the search sensitivity through the lvjj channel at the 7TeV LHC on relevant new physics, via probing the hard tails on the reconstructed Mlvjj and the transverse momentum of W-boson (PTW), taking into account main backgrounds and including the parton shower and detector simulation effects. Our results show that with integrated luminosity of 5fb-1, the LHC can already discovery or exclude a large parameter region of the new physics, e.g., 95% CL. limit can be set on the Large Extra Dimensions with a cut-off scale up to 1.5 TeV, and the WWZ anomalous coupling down to, e.g. |\lambda_Z|~0.1. Brief results are also given for the 8TeV LHC.Comment: 13 pages, 6 figures, 2 table

    A sensitivity study of triboson production processes to dimension-6 EFT operators at the LHC

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    We present the first parton-level study of anomalous effects in triboson production in both fully and semi-leptonic channels in proton-proton collisions at 13 TeV at the Large Hadron Collider (LHC). The sensitivity to anomalies induced by a minimal set of bosonic dimension-6 operators from the Warsaw basis is evaluated with specific analyses for each final state. A likelihood-based strategy is employed to assess the most sensitive kinematic observables per channel, where the contribution of Effective Field Theory operators is parameterized at either the linear or quadratic level. The impact of the mutual interference terms of pairs of operators on the sensitivity is also examined. This benchmark study explores the complementarity and overlap in sensitivity between different triboson measurements and paves the way for future analyses at the LHC experiments. The statistical combination of the considered final states allows setting stringent bounds on five bosonic Wilson coefficients

    Research of Regional Air Transportation Development Strategy in China

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    支线航空运输作为民航运输体系中重要的组成部分,其持续、健康、快速的发展无论对区域经济的推动,民航行业的发展,振兴我国航空工业乃至构建和谐社会等各个层面都具有重大意义。 然而,与我国民航运输总体的高速发展不相称的是,支线航空的发展却一直非常缓慢,徘徊不前。本文试图通过深入的分析和研究,从行业宏观角度及航空公司的微观角度揭示我国支线航空发展存在的问题及其根源,并有针对性地提出促进支线航空发展的策略建议。 本文首先以中外业界广为接受和认同的支线航空运输市场的界定标准为基础,结合我国国情和发展的观念对我国支线航空市场作出了界定。在此基础上,结合行业生命周期理论,通过研究欧美发达航空市场的支线航空发...As an important part of civil air transportation system, regional air transportation is the key to boost the regional economy; improve the civil air transportation industry; support the Chinese aviation manufacturing industry as well as build the harmonious society. However, unlike the fast development of the whole civil air transportation industry, regional air transportation develops very slowl...学位:工商管理硕士院系专业:管理学院工商管理教育中心(MBA中心)_工商管理硕士(MBA)学号:20031503

    Milt androgen profile and evaluation of sperm morpho-functional characteristics of wild-caught and farmed European eels (Anguilla anguilla)

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    Evaluating milt samples before their preservation and/or reproductive use is critical to correctly develop assisted reproductive strategies for teleost species. This is especially true in case of “critically endangered” species, like the European eel (Anguilla anguilla), whose life cycle is not closed yet, leading to the necessity of capturing younglings from natural populations for both research and productive purposes. Despite androgens being involved in spermatogenesis and playing pivotal roles in the pre-migratory morphological and physiological changes, their quantification in different biological tissues is still to be refined in European eels. The aim of this study was to evaluate the feasibility of extraction and quantification of testosterone (T) and 11-ketotestosterone (11-KT) from male European eel milts. The secondary aim was to investigate potential differences in androgens’ profiles and/or functional characteristics of spermatozoa between wild-caught and farmed specimens. Twenty-four male European eels obtained from the North Adriatic region (14 wild-caught and 10 farmed) underwent a maturation-inducing hormonal treatment for milt production; blood and milt samples were then collected for androgens quantification upon ELISA and RIA methodologies. Spermatozoa were also evaluated for viability and objective motility. Plasma showed average T and 11-KT levels of 2.32 and 6.88 ng/mL, respectively, while milt 0.24 (T) and 1.09 ng/mL (11-KT). Significantly higher spermatozoa concentrations and motility were observed in farmed eels’ milts. This work contributes to deepening the knowledge on teleost physiology, being the first report quantifying T and 11-KT from European eels’ seminal plasma and comparing the quality of milts of farmed vs wild specimens
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