Natural Course of Uncorrected Visual Acuity of Chidren in Primary Schools and the Relationship between Uncorrected Visual Acuity and Life Habits

Quantitative Tool. (PDF 219 kb

Bivariate and multivariate logistic regression model of the odds of having a large lesion diagnosed at the first VIA screening, by HIV status and facility characteristics, all countries combined.

<p>(r) Reference category</p><p>Bivariate and multivariate logistic regression model of the odds of having a large lesion diagnosed at the first VIA screening, by HIV status and facility characteristics, all countries combined.</p

Cervical cancer screening and treatment outcomes in three countries.

<p>Cervical cancer screening and treatment outcomes in three countries.</p

Bivariate and multivariate logistic regression model of the odds of screening VIA positive, by HIV status and facility characteristics, all countries combined.^*

<p>(r) Reference category</p><p>* The total number of women included in this analysis is lower than the total number of women screened due to missing variables for some women, who were excluded from analysis.</p><p>Bivariate and multivariate logistic regression model of the odds of screening VIA positive, by HIV status and facility characteristics, all countries combined.^{<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0139242#t003fn002" target="_blank">*</a>}</p

Baseline facility and provider characteristics, by country.

<p>Baseline facility and provider characteristics, by country.</p

Additional file 1: of Program assessment of efforts to improve the quality of postpartum counselling in health centers in Morogoro region, Tanzania

Table S1. Reported supervision provided to RCH providers (n = 88) from July 2011 to June 2012. (DOCX 31 kb

Table_1_Outcome of patients with stage I immature teratoma after surveillance or adjuvant chemotherapy.docx

ObjectiveImmature teratomas are rare malignant ovarian germ cell tumours, typically diagnosed in young women, where fertility-sparing surgery is the treatment of choice. The role of adjuvant chemotherapy in stage I disease remains controversial. We evaluated the impact of surveillance versus chemotherapy on the recurrence rate in stage I immature teratomas.MethodsWe collected a single centre retrospective series of patients with stage I immature teratomas treated with fertility-sparing surgery at San Gerardo Hospital, Monza, Italy, between 1980 and 2019. Potential risk factors for recurrence were investigated by multivariate logistic regression.ResultsOf the 74 patients included, 12% (9/74) received chemotherapy, while 88% (65/74) underwent surveillance. Median follow-up was 188 months. No difference in recurrence was found in stage IA/IB and IC immature teratomas [10% (6/60) vs. 28.6% (4/14) (P=0.087)], grade 1, grade 2, and grade 3 [7.1% (2/28) vs. 14.3% (4/28) vs. 22.2% (4/18) (p=0.39)], and surveillance versus chemotherapy groups [13.9% (9/65) vs. 11.1% (1/9)) (p = 1.00)]. In univariate analysis, the postoperative approach had no impact on recurrence. The 5-year disease-free survival was 87% and 90% in the surveillance and chemotherapy groups, respectively; the overall survival was 100% in both cohorts.ConclusionsOur results support the feasibility of surveillance in stage I immature teratomas. Adjuvant chemotherapy may be reserved for relapses. However, the potential benefit of chemotherapy should be discussed, especially for high-risk tumours. Prospective series are warranted to confirm our findings.What is already known on this topicTo date, no consensus has been reached regarding the role of adjuvant chemotherapy in stage I immature teratomas of the ovary. Some studies suggest that only surveillance is an acceptable choice. However, guidelines are not conclusive on this topic.What this study addsNo difference in terms of recurrence was observed between the surveillance and the adjuvant chemotherapy group. All patients who relapsed were successfully cured with no disease-related deaths.How this study might affect research, practice or policyAdjuvant chemotherapy should be appropriately discussed with patients. However, it may be reserved for relapse according to our data.</p

Additional file 1: Figure S1. of Profile, knowledge, and work patterns of a cadre of maternal, newborn, and child health CHWs focusing on preventive and promotive services in Morogoro Region, Tanzania

Overview of Integrated Program MNCH CHW rollout per district. Figure S2. Mean composite scores for CHW knowledge and reported service provision on maternal and child health care across the continuum of care and for specific services. Figure S3. Observed use of job aids during pregnancy home visits (n = 37). Table S1. Ordered logistic regression models for composite scores for overall CHW knowledge and specific sub-domains of pregnancy, postpartum, newborn care, and child health controlling for gender, date of training, education, age, and assets. Table S2. Ordered logistic regression models for composite scores for family planning, infection/injury prevention, malaria, HIV transmission, and nutrition controlling for gender, date of training, education, age, and assets