Long-term survival by etiology.

<p>The median survival was significantly longer in HCV-related HCC patients than in HBV-related HCC patients. (2.17 vs. 1.34 years, <i>P</i><0.01).</p

Adjusted difference in the survival between hepatitis B virus and hepatitis C virus related hepatocellular carcinoma by subgroup.

<p>Abbreviation: HBV, hepatitis B virus; HCV, hepatitis C virus; CI, confidence interval; NR, not reached. In each adjusted model, hepatitis B was used as reference for hepatitis C and following variables were adjusted: age, gender, Child-Pugh class, AJCC/mUICC stage, and initial treatment modality.</p><p>Adjusted difference in the survival between hepatitis B virus and hepatitis C virus related hepatocellular carcinoma by subgroup.</p

Characteristics of study population.

<p>Abbreviation: HBV, hepatitis B virus; HCV, hepatitis C virus; S.D, standard deviation; INR, international normalized ratio; AJCC/mUICC, American Joint Committee on Cancer/International Union Against Cancer; BCLC, Barcelona Clinic Liver Cancer; TACE, transarterial chemoembolization; TACI, transarterial chemoinfusion.</p><p>*These 3 patients received ¹⁶⁶holmium injection therapy. Values are expressed as mean ± standard deviation, median (quartile), or no (%).</p>†<p>BCLC stage and performance status was not collected at the time of data collection. Hence, BCLC stage was re-coded (staged) by authors with Child-Pugh class, tumor size, tumor number and presence of portal vein invasion and extrahepatic spread, without performance status.</p><p>Characteristics of study population.</p

Baseline characteristics of study participants by group (N = 13,806).

Baseline characteristics of study participants by group (N = 13,806).</p

Comparison of prognostic factors between hepatitis B virus- and hepatitis C virus-related hepatocellular carcinoma.

<p>Abbreviation: HBV, hepatitis B virus; HCC, hepatocellular carcinoma; HCV, hepatitis C virus; HR, hazard ratio.</p><p>Comparison of prognostic factors between hepatitis B virus- and hepatitis C virus-related hepatocellular carcinoma.</p

Ratio of annual change rates in the coronary artery calcium scores by SLD severity.

Ratio of annual change rates in the coronary artery calcium scores by SLD severity.</p

The age-specific incidence rates of hepatocellular carcinoma (HCC) by the etiology (A), by gender in HBV-related HCC (B) and by gender in HCV-related HCC (C).

<p>The annual incidence rates of HBV-related HCC peaked in the 50–59 age group, while the annual incidence rates of HCV-related HCC kept gradually increasing until age ≥70 s. Similar trend was observed after stratified by gender, although the peak mean annual incidence rates was observed in the 50–59 in men and in the 60–69 in women in HBV-related HCC (B). Diamonds (♦) and triangles (▴) represent for HBV and HCV-related HCC in (A), men and women in (B) and (C), respectively.</p

Survival by etiology.

<p>Abbreviation: HBV, hepatitis B virus; HCV, hepatitis C virus. HR, hazard ratio. Model 1  =  crude hazard ratio, Model 2  =  adjusted for age, gender, Model 3  =  Model 2 + Child-Pugh class and AJCC/mUICC stage, Model 4  =  Model 3 + initial treatment modality.</p><p>Survival by etiology.</p

Additional file 1 of Modest alcohol intake and mortality in individuals with elevated alanine aminotransferase levels: a nationwide cohort study

Additional file 1: Table S1. Multivariable-adjusted hazard ratios for liver-related and all-cause mortality associated with alcohol intake by alanine aminotransferase (ALT) level status in sensitivity analyses. Table S2. Multivariable-adjusted hazard ratios for liver-related and all-cause mortality associated with elevated alanine aminotransferase (ALT) levels by alcohol intake status in sensitivity analyses

Ratio of annual change rates in the coronary artery calcium scores of participants (N = 13,811).

Ratio of annual change rates in the coronary artery calcium scores of participants (N = 13,811).</p