4 research outputs found

    Guiding AMR Parsing with Reverse Graph Linearization

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    Abstract Meaning Representation (AMR) parsing aims to extract an abstract semantic graph from a given sentence. The sequence-to-sequence approaches, which linearize the semantic graph into a sequence of nodes and edges and generate the linearized graph directly, have achieved good performance. However, we observed that these approaches suffer from structure loss accumulation during the decoding process, leading to a much lower F1-score for nodes and edges decoded later compared to those decoded earlier. To address this issue, we propose a novel Reverse Graph Linearization (RGL) enhanced framework. RGL defines both default and reverse linearization orders of an AMR graph, where most structures at the back part of the default order appear at the front part of the reversed order and vice versa. RGL incorporates the reversed linearization to the original AMR parser through a two-pass self-distillation mechanism, which guides the model when generating the default linearizations. Our analysis shows that our proposed method significantly mitigates the problem of structure loss accumulation, outperforming the previously best AMR parsing model by 0.8 and 0.5 Smatch scores on the AMR 2.0 and AMR 3.0 dataset, respectively. The code are available at https://github.com/pkunlp-icler/AMR_reverse_graph_linearization.Comment: Findings of EMNLP202

    Genetic Basis of Virulence Attenuation Revealed by Comparative Genomic Analysis of Mycobacterium tuberculosis Strain H37Ra versus H37Rv

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    Tuberculosis, caused by Mycobacterium tuberculosis, remains a leading infectious disease despite the availability of chemotherapy and BCG vaccine. The commonly used avirulent M. tuberculosis strain H37Ra was derived from virulent strain H37 in 1935 but the basis of virulence attenuation has remained obscure despite numerous studies. We determined the complete genomic sequence of H37Ra ATCC25177 and compared that with its virulent counterpart H37Rv and a clinical isolate CDC1551. The H37Ra genome is highly similar to that of H37Rv with respect to gene content and order but is 8,445 bp larger as a result of 53 insertions and 21 deletions in H37Ra relative to H37Rv. Variations in repetitive sequences such as IS6110 and PE/PPE/PE-PGRS family genes are responsible for most of the gross genetic changes. A total of 198 single nucleotide variations (SNVs) that are different between H37Ra and H37Rv were identified, yet 119 of them are identical between H37Ra and CDC1551 and 3 are due to H37Rv strain variation, leaving only 76 H37Ra-specific SNVs that affect only 32 genes. The biological impact of missense mutations in protein coding sequences was analyzed in silico while nucleotide variations in potential promoter regions of several important genes were verified by quantitative RT-PCR. Mutations affecting transcription factors and/or global metabolic regulations related to in vitro survival under aging stress, and mutations affecting cell envelope, primary metabolism, in vivo growth as well as variations in the PE/PPE/PE-PGRS family genes, may underlie the basis of virulence attenuation. These findings have implications not only for improved understanding of pathogenesis of M. tuberculosis but also for development of new vaccines and new therapeutic agents

    Real-Time Video Super-Resolution on Smartphones with Deep Learning, Mobile AI 2021 Challenge: Report

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    Video super-resolution has recently become one of the most important mobile-related problems due to the rise of video communication and streaming services. While many solutions have been proposed for this task, the majority of them are too computationally expensive to run on portable devices with limited hardware resources. To address this problem, we introduce the first Mobile AI challenge, where the target is to develop an end-to-end deep learning-based video super-resolution solutions that can achieve a real-time performance on mobile GPUs. The participants were provided with the REDS dataset and trained their models to do an efficient 4X video upscaling. The runtime of all models was evaluated on the OPPO Find X2 smartphone with the Snapdragon 865 SoC capable of accelerating floating-point networks on its Adreno GPU. The proposed solutions are fully compatible with any mobile GPU and can upscale videos to HD resolution at up to 80 FPS while demonstrating high fidelity results. A detailed description of all models developed in the challenge is provided in this paper.N
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