Clinical and radiographic outcomes of upper thoracic versus lower thoracic upper instrumented vertebrae for adult scoliosis: a meta-analysis

<div><p>The aim of this study was to evaluate the clinical and radiographic outcomes of upper thoracic (UT) versus lower thoracic (LT) upper instrumented vertebrae (UIV) for adult scoliosis by meta-analysis. We conducted a literature search in three databases to retrieve related studies up to March 15, 2017. The preliminary screened studies were assessed by two reviewers according to the selection criteria. All analyses were carried out using the statistical software package R version 2.31. Odds ratios (OR) with 95% confidence intervals (CI) were used to describe the results. The I2 statistic and Q statistic test were used for heterogeneity assessment. Egger's test was performed to detect publication bias. To assess the effect of each study on the overall pooled OR or standardized mean difference (SMD), sensitive analysis was conducted. Ten trials published between 2007 and 2015 were eligible and included in our study. Meta-analysis revealed that the UT group was associated with more blood loss (SMD=0.4779, 95%CI=0.3349-0.6209, Z=6.55, P<0.0001) and longer operating time (SMD=0.5780, 95%CI=0.1971-0.958, Z=2.97, P=0.0029) than the LT group. However, there was no significant difference in Oswestry Disability Index, Scoliosis Research Society (SRS) function subscores, radiographic outcomes including sagittal vertical axis, lumbar lordosis, and thoracic kyphosis, length of hospital stay, and revision rates between the two groups. No evidence of publication bias was found between the two groups. Fusion from the lower thoracic spine (below T10) has as advantages a shorter operation time and less blood loss than upper thoracic spine (above T10) in posterior long-segment fixation for degenerative lumbar scoliosis.</p></div

Datasets.zip from An ion trap design for a space-deployable strontium-ion optical clock

A folder with the datasets part of this study

Integrated photonics enables continuous-beam electron phase modulation

The ability to tailor laser light on a chip using integrated photonics has allowed for extensive control over fundamental light-matter interactions in manifold quantum systems including atoms, trapped ions, quantum dots, and defect centers. Free electrons, enabling high-resolution microscopy for decades, are increasingly becoming the subject of laser-based quantum manipulation. Using free-space optical excitation and intense laser pulses, this has led to the observation of free-electron quantum walks, attosecond electron pulses, and imaging of electromagnetic fields. Enhancing the interaction with electron beams through chip-based photonics promises unique applications in nanoscale quantum control and sensing, but has yet to enter electron microscopy. Here, we merge integrated photonics with electron microscopy, demonstrating coherent phase modulation of an electron beam using a silicon nitride microresonator driven by a continuous-wave laser. The high-Q factor (~$10^6$) cavity enhancement and a waveguide designed for phase matching lead to efficient electron-light scattering at unprecedentedly low, few-microwatt optical powers. Specifically, we fully deplete the initial electron state at a cavity-coupled power of 6 $\mu$W and create >500 photon sidebands for only 38 mW in the bus waveguide. Moreover, we demonstrate $\mu$eV electron energy gain spectroscopy (EEGS). Providing simultaneous optical and electronic spectroscopy of the resonant cavity, the fiber-coupled photonic structures feature single-mode electron-light interaction with full control over the input and output channels. This approach establishes a versatile framework for exploring free-electron quantum optics, with future developments in strong coupling, local quantum probing, and electron-photon entanglement. Our results highlight the potential of integrated photonics to efficiently interface free electrons and light

Cavity-mediated electron-photon pairs

Advancing quantum information, communication and sensing relies on the generation and control of quantum correlations in complementary degrees of freedom. Here, we demonstrate the preparation of electron-photon pair states using the phase-matched interaction of free electrons with the evanescent vacuum field of a photonic-chip-based optical microresonator. Spontaneous inelastic scattering produces intracavity photons coincident with energy-shifted electrons. Harnessing these pairs for correlation-enhanced imaging, we achieve a two-orders of magnitude contrast improvement in cavity-mode mapping by coincidence-gated electron spectroscopy. This parametric pair-state preparation will underpin the future development of free-electron quantum optics, providing a pathway to quantum-enhanced imaging, electron-photon entanglement, and heralded single-electron and Fock-state photon sources