Step response and impulse response of the genes to perturbation of silica in cultured fibroblasts.

<p>Step response and impulse response of the genes to perturbation of silica in cultured fibroblasts.</p

Root-locus of gene expression in SSc fibroblasts.

<p>Root-locus of gene expression in SSc fibroblasts.</p

Scheme of a SISO system

<p>Scheme of a SISO system</p

Eigenvalues of the transition matrix A of the state-space model for the genes in a regulatory network responding to silica in cultured human normal and SSc fibroblasts.

<p>Eigenvalues of the transition matrix A of the state-space model for the genes in a regulatory network responding to silica in cultured human normal and SSc fibroblasts.</p

State-space model for the regulatory gene network responding to silica stimulation in cultured human fibroblasts.

<p>The numbers next to the edges are the coefficients in the state-space equations for the normal (black color) and SSc (red color) fibroblasts, respectively. The numbers in the boxes denote the mean expression values of the genes in normal (black color) and SSc (red color) fibroblasts.</p

Root-locus of gene expression in normal fibroblasts.

<p>Root-locus of gene expression in normal fibroblasts.</p

Unit step signal and impulse signal.

<p>Unit step signal and impulse signal.</p

Characteristics of patients with and without ECG abnormalities in the GENISOS Study Population.

<p>Characteristics of patients with and without ECG abnormalities in the GENISOS Study Population.</p

Frequencies of different ECG findings and their impact on mortality in the GENISOS cohort.

<p>Frequencies of different ECG findings and their impact on mortality in the GENISOS cohort.</p

Association of ECG findings with low ejection fraction and elevated right ventricular systolic pressure on echocardiogram.

<p>Association of ECG findings with low ejection fraction and elevated right ventricular systolic pressure on echocardiogram.</p