The effects of antidepressants appear to be rapid and at environmentally relevant concentrations

The effects of antidepressants on wildlife are currently raising some concern because of an increased number of publications indicating biological effects at environmentally relevant concentrations (\u3c100 ng/L). These results have been met with some scepticism because of the higher concentrations required to detect effects in some species and the perceived slowness to therapeutic effects recorded in humans and other vertebrates. Because their mode of action is thought to be by modulation of the neurotransmitters serotonin, dopamine, and norepinephrine, aquatic invertebrates that possess transporters and receptors sensitive to activation by these pharmaceuticals are potentially affected by them. The authors highlight studies on the effects of antidepressants, particularly on crustacean and molluskan groups, showing that they are susceptible to a wide variety of neuroendocrine disruptions at environmentally relevant concentrations. Interestingly, some effects observed in these species can be observed within minutes to hours of exposure. For example, exposure of amphipod crustaceans to several selective serotonin reuptake inhibitors can invoke changes in swimming behavior within hours. In mollusks, exposure to selective serotonin reuptake inhibitors can induce spawning in male and female mussels and foot detachment in snails within minutes of exposure. In the light of new studies indicating effects on the human brain from selective serotonin reuptake inhibitors using magnetic resonance imaging scans, the authors discuss possible reasons for the discrepancy in former results in relation to the read-across hypothesis, variation in biomarkers used, modes of uptake, phylogenetic distance, and the affinity to different targets and differential sensitivity to receptors

Relay-proof channels using UWB lasers

Alice is a hand-held device. Bob is a device providing a service, such as an ATM, an automatic door, or an anti-aircraft gun pointing at the gyro-copter in which Alice is travelling. Bob and Alice have never met, but share a key, which Alice uses to request a service from Bob (dispense cash, open door, don't shoot). Mort pretends to Bob that she is Alice, and her accomplice Cove pretends to Alice that he is Bob. Mort and Cove relay the appropriate challenges and responses to one another over a channel hidden from Alice and Bob. Meanwhile Alice waits impatiently in front of a different ATM, or the wrong door, or another gun. How can such an attack be prevented?Final Accepted Versio

Shape and size of the arenas affect amphipod behaviours: implications for ecotoxicology

The use of behaviour in ecotoxicology is expanding, however the lack of standardisation and validation of these assays currently presents a major drawback in moving forward in the development of behavioural assays. Furthermore, there is a current paucity of control data on test species, particularly invertebrate models. In this study we assessed a range of behaviours associated with spatial distribution and locomotion in relation to arena size and shape in two species of amphipod crustacean (Echinogammarus marinus and Gammarus pulex). Arena shape had significant effects on almost all behavioural parameters analysed. Increasing arena size resulted in an increased mean velocity and activity plus increased proportional use of the central zones. These results indicate that ‘ceiling effects’ may occur in some ecotoxicological studies resulting in potentially ‘false’ negative effects if careful consideration is not paid to experimental design. Differences in behaviours were observed between the two species of amphipod. For example, G. pulex spend approximately five times (∼20%) more of the available time crossing the central zones of the arenas compared to E. marinus (∼4%) which could have implications on assessing anxiolytic behaviours. The results of this study highlight several behaviours with potential for use in behavioural ecotoxicology with crustaceans but also underscore the need for careful consideration when designing these behavioural assays

Pronounced and prevalent intersexuality does not impede the ‘Demon Shrimp’ invasion

Crustacean intersexuality is widespread and often linked to infection by sex-distorting parasites. However, unlike vertebrate intersexuality, its association with sexual dysfunction is unclear and remains a matter of debate. The ‘Demon Shrimp,’ Dikerogammarus haemobaphes, an amphipod that has invaded continental waterways, has recently become widespread in Britain. Intersexuality has been noted in D. haemobaphes but not investigated further. We hypothesise that a successful invasive population should not display a high prevalence of intersexuality if this condition represents a truly dysfunctional phenotype. In addition, experiments have indicated that particular parasite burdens in amphipods may facilitate invasions. The rapid and ongoing invasion of British waterways represents an opportunity to determine whether these hypotheses are consistent with field observations. This study investigates the parasites and sexual phenotypes of D. haemobaphes in British waterways, characterising parasite burdens using molecular screening, and makes comparisons with the threatened Gammarus pulex natives. We reveal that invasive and native populations have distinct parasitic profiles, suggesting the loss of G. pulex may have parasite-mediated eco-system impacts. Furthermore, the parasite burdens are consistent with those previously proposed to facilitate biological invasions. Our study also indicates that while no intersexuality occurs in the native G. pulex, approximately 50% of D. haemobaphes males present pronounced intersexuality associated with infection by the microsporidian Dictyocoela berillonum. This unambiguously successful invasive population presents, to our knowledge, the highest reported prevalence of male intersexuality. This is the clearest evidence to date that such intersexuality does not represent a form of debilitating sexual dysfunction that negatively impacts amphipod populations

Chaotic Dynamics of a Free Particle Interacting Linearly with a Harmonic Oscillator

We study the closed Hamiltonian dynamics of a free particle moving on a ring, over one section of which it interacts linearly with a single harmonic oscillator. On the basis of numerical and analytical evidence, we conjecture that at small positive energies the phase space of our model is completely chaotic except for a single region of complete integrability with a smooth sharp boundary showing no KAM-type structures of any kind. This results in the cleanest mixed phase space structure possible, in which motions in the integrable region and in the chaotic region are clearly separated and independent of one another. For certain system parameters, this mixed phase space structure can be tuned to make either of the two components disappear, leaving a completely integrable or completely chaotic phase space. For other values of the system parameters, additional structures appear, such as KAM-like elliptic islands, and one parameter families of parabolic periodic orbits embedded in the chaotic sea. The latter are analogous to bouncing ball orbits seen in the stadium billiard. The analytical part of our study proceeds from a geometric description of the dynamics, and shows it to be equivalent to a linked twist map on the union of two intersecting disks.Comment: 17 pages, 11 figures Typos corrected to display section label