2,209 research outputs found

    A method to assess the application of additive manufacturing to inventory replenishment : a thesis presented in partial fulfilment of the requirements for the Master of Supply Chain Management at Massey University, Albany, New Zealand

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    Companies have historically struggled to deal with their stock, especially the long inventory tail. As most of the inventory management techniques that deal with slow-moving stock have proved to be rather inefficient, this research investigates the use of additive manufacturing to 3D print items on demand and therefore mitigate the inventory carrying and associated costs. This research has been applied to a Hydraulic Equipment Business in New Zealand, which was tested through an inequation that models the traditional manufacturing and 3D printing costs, yielding the ‘tipping point’ for the use of the 3D printing technology. Even though the results obtained herein were negative for this particular case regarding the use of additive manufacturing, this research has developed a methodology to assess the trade-off between traditional manufacturing and 3D printing and also provides insights into the characteristics of the inventory of the businesses that are most likely to benefit from the use of the technology

    Pervasive gaps in Amazonian ecological research

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    Alterações cognitivas na infecção pelo HIV: uma revisão sistemática: Cognitive changes in HIV infection: a systematic review

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    Provocada pelo vírus da imunodeficiência humana, com a síndrome da imunodeficiência adquirida, numa pessoa tem o seu sistema imunológico prejudicado, tornando-se suscetível a outras doenças e infecção. Tem-se a estimativa de que 50% dos infectados com o referido vírus podem sofrer alterações cognitivas. Diante disso, este estudo tem como objetivo refletir sobre mudanças estruturais cerebrais e comprometimento cognitivo em pacientes com HIV. Portanto, trata-se de uma revisão sistemática de literatura, desenvolvida a partir da seleção de estudos nas bases de dados Scielo, Pubmed e BVS/Medline a partir do uso de descritores DeCS/MeSH e aplicação de critérios de inclusão e exclusão. Após a análise e interpretação dos dados, concluiu-se que há uma significativa prevalência de HAND em adultos infectados por HIV, no que se refere a alterações cognitivas, especialmente entre pacientes do sexo feminino, de baixa escolaridade e renda, com diagnóstico tardio e baixa quantidade de linfócitos CD4 no início do tratamento. Entre essas pessoas, revelam-se comprometimentos quanto à memória, atenção, controle de impulsos, velocidade de processamento e motora, dentre outros

    Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an

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    Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis

    Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches