1,203 research outputs found

    Transcript for Episode 06: New Kids on the Block: Forrest Anderson Brings Baby Boomers into Montana Government

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    https://digitalcommons.mtech.edu/crucible_transcriptions/1005/thumbnail.jp

    Budget Perspectives 2013. RESEARCH SERIES NUMBER 28 September 2012

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    The annual Budget Perspectives Conference provides a forum for discussing key public policy issues of both immediate and longer term concern. In the context of the current fiscal and economic crisis, research insights are needed at both the macro and micro level. The former are central to understanding and managing the significant reductions in the budget deficit needed to put Ireland's public finances on a sustainable footing. The latter are essential because a successful budgetary adjustment requires restructuring of both public expenditure and taxation. This in turn requires that policy adjustments take full account of both efficiency and equity issue and are seen to do so. The research papers presented at this year's annual Budget Perspectives Conference continue in this tradition, providing an opportunity for policymakers, social partners and researchers to engage with some of the major current issues

    Researching trust in the police and trust in justice: a UK perspective

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    This paper describes the immediate and more distant origins of a programme of comparative research that is examining cross-national variations in public trust in justice and in the police. The programme is built around a module of the fifth European Social Survey, and evolved from a study funded by the European Commission. The paper describes the conceptual framework within which we are operating – developed in large measure from theories of procedural justice. It reviews some of the methodological issues raised by the use of sample surveys to research issues of public trust in the police, public perceptions of institutional legitimacy and compliance with the law. Finally it gives a flavour of some of the early findings emerging from the programme

    DOCK8 Functions as an Adaptor that Links TLR–MyD88 Signaling to B Cell Activation

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    DOCK8 and MyD88 have been implicated in serologic memory. Here we report antibody responses were impaired and CD27+CD27^+ memory B cells were severely reduced in DOCK8-deficient patients. Toll-like receptor 9 (TLR9)- but not CD40-driven B cell proliferation and immunoglobulin production were severely reduced in DOCK8-deficient B cells. In contrast, TLR9-driven expression of AICDA, CD23 and CD86, and activation of NF-κB, p38 and Rac1 were intact. DOCK8 associated constitutively with MyD88 and the tyrosine kinase Pyk2 in normal B cells. Following TLR9 ligation, DOCK8 became tyrosine phosphorylated by Pyk2, bound the Src family kinase Lyn and linked TLR9 to a Src-Syk-STAT3 cascade essential for TLR9-driven B cell proliferation and differentiation. Thus, DOCK8 functions as an adaptor in a TLR9-MyD88 signaling pathway in B cells

    Display platforms of Albert’s Lyrebird Menura alberti, Part 1. Influence of habitat on location and characteristics

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    Male Albert’s Lyrebirds perform multimodal displays on platforms to attract potential mates during their winter breeding season. We documented the characteristics of 62 display platforms belonging to seven males within 40 ha of cool-subtropical rainforest and wet sclerophyll forest with a mesic understory and we used time-lapse photography and video to record Lyrebird behaviour over 12 months. Display platforms were categorised by physical features into four types, largely reflecting habitat. The platforms were actively prepared and maintained by the male up to two months before display activity peaked. All platforms were elevated above ground level, either due to mounding (in wet sclerophyll) or the presence of vines (in rainforest). In the rainforest, the majority of platforms were situated directly under narrow openings in the canopy; if not, the canopy openings were mostly northeast-ENE of the platform, aligning with the azimuth of the sun at sunrise during winter. In the wet sclerophyll, however, display platforms were invariably situated directly below large canopy openings, as expected in well-lit, semi-open habitat. During displays, males in rainforest rapidly raised and lowered the vines on their platforms with their feet, causing the entwined surrounding vegetation to shake. All display platforms were surrounded by a screen of vegetation. Of the 25 vegetative screening species in the rainforest, nine were also present on the platforms and were predominantly vines of the genera Cissus (43%) and Parsonsia (33%). In the wet sclerophyll, platforms were composed of plant material from only four species, none of which were vines. Based on our observations, we propose that male Albert’s Lyrebirds in the rainforest select display sites that enhance visualisation of their display performances through elevation of the platform by mounding, focussed lighting from canopy openings, and the rapid movement of screening vegetation entangled by platform vines. These findings contrast strongly with those of a recent study that concluded that there were no differences between display platforms and nearby random points in ground height, canopy openings or vegetative screening. We suggest that the disparate findings of the two studies are partly due to differences in the habitats sampled. Our study was conducted mostly in cool subtropical rainforest, where the uneven multi-layered canopy prevents most light from reaching the forest floor, and vines are abundant, whereas the previous study was conducted mainly in temperate rainforest, where the flora is less diverse and the thinner, less complex canopy results in much greater illumination
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