Quality of life patients with type 2 diabetes among patients aged 65-75 years

Introduction: Type 2 diabetes is a chronic disease that contributes to the occurrence of limitations in the patient's life. In order to assess the quality of life of patients with diabetes, the following aspects should be taken into account: age, gender, education, presence of complications, Material and methods: The study was conducted using the diagnostic survey method. The research tools were: a survey questionnaire consisting of metrics and clinical parameters, the ADDQoL questionnaire, The study was conducted on a group of 104 patients (including 58 women and 46 men) in the Diabetes Clinic at the Provincial Hospital in Bielsko-Biała in the period from April 20, 2018 to September 1, 2018. Results: Diabetes has been shown to have a negative impact on all 19 ADDQoL domains. The most negative feelings concern the future, freedom in eating, and enjoying leisure activities. Conclusions: Patients with type 2 diabetes have a negative impact on their quality of life. Patients with diabetes require greater focus on educational activities aimed at adhering to a rational diet and psychological support

Die Visiertracheotomie – eine retrospektive Analyse der postoperativen Komplikationen im Vergleich zur Tracheotomie mit einem kaudal gestielten Knorpellappen

Introduction: For decades the tracheostomy using a Bjoerk-flap has been the standard procedure to create a reliable epithelialized tracheostomy in head and neck tumor surgery. Creating the Bjoerk-flap requires splitting 1-2 tracheal rings causing potential tracheal instability and tissue trauma. As a surgical alternative the visor tracheostomy allows to create an epithelialized tracheostomy without splitting tracheal rings. The aim of this work was to prove the safety of the visor tracheotomy method due to peri- and early postoperative complications. Material and Methods: Data from surgical protocols and patient charts were evaluated retrospectively. Complications such as infection, bleeding, granulation, tube dislocation and tracheostoma stenosis of 139 tracheostomies with Bjoerk flap method and 109 visor tracheostomies were compared. Results: The results of our clinical data showed no significant differences due to risk and complications between the two compared techniques. The data proved the safety of this "new method", especially in early postoperative complication rate.Einleitung: Zur Anlage einer chirurgischen Tracheotomie sind unterschiedliche Techniken bekannt. Die Björktracheotomie ist eine Anwendung der Tracheotomie und sieht das Einschneiden eines kaudal gestielten Trachealfensters vor. Dieses wird im Anschluss zur Bildung einer mukokutanen Brücke mit der Halshaut vernäht. (1) Das Verfahren ist durch unzählige Studien und klinischer Erfahrung seit mehr als fünfzig Jahren in seiner Sicherheit belegt. (2-8) Zuletzt stellten Probst et al. eine „neue Technik“ als interkartilaginäre Trachealknorpelerhaltende Visiertracheotomie vor und untersuchten die Technik im postoperativen Verlauf an 48 Patienten im Jahr 2004. Bei dieser Technik wird nicht wie bei der Björktracheotomie ein tracheales Fenster angelegt und zur Bildung einer mukokutanen Brücke mit der Halshaut vernäht, sondern die Trachea nach Anlage eines interkartilaginären Schnitts visierartig aufgeklappt und kranial und kaudal mit der Halshaut vernäht. Vorteile dieser Technik sahen die Autoren in der Gewebeschonung, dem Erhalt der Trachealspangen und der einfachen Wiederverschließbarkeit, die bei der Björktracheotomie oft durch die Degeneration der Trachealspangen nur erschwert möglich ist. (9) Ziel unserer Arbeit war es, die bereits etablierte Anwendung der Björktracheotomie mit der Visiertracheotomie zu vergleichen und anhand der aufgetretenen postoperativen Komplikationen retrospektiv die Sicherheit der Visiertracheotomie statistisch zu überprüfen. Material und Methoden: Im Setting einer unizentrisch retrospektiven Kohortenstudie untersuchten wir postoperativ aufgetretene Komplikationen, wie unter anderem Wundinfektion, Blutung, Granulation, Dehiszenz und Trachealstenose durch Vergleich von 139 Björktracheotomien und 109 Visiertracheotomien 2012 bis 2015 durchgeführt wurden. Ergebnisse: Zwischen den beiden Verfahren konnte kein statistisch signifikanter Unterschied hinsichtlich der postoperativ aufgetretenen Komplikationen belegt werden. Im Beobachtungszeitraum traten keine schwerwiegenden Komplikationen oder Tracheotomie assoziierte Tode auf. Die Visiertracheotomie konnten wir als sicheres Verfahren im Vergleich zur bereits etablierten Björktracheotomie belegen.64, viii Seite

An Introduction to Design a Digital Twin for an Industry 4.0 Training Production Line

Contribution presents a simplified practical procedure for the implementation of Asset administration shells (AAS) of assets from the Festo Didactic Cyber-Physical Factory for Industry 4.0 training and therefore is intended for designers, students and all those interested in the field of Industry 4.0 technologies, standards and procedures. It could be also a small guide for introduction users of AAS as the very standardized digital twin for Industry 4.0 technology and standards

Entrepreneurship Performance Deutscher Hochschulen 2023: Munich Impact Study

Ziele Neben den traditionellen Aufgaben von Forschung und Lehre etabliert sich bei Hochschulen zunehmend die "Third Mission“ als zusätzliche Aufgabe, d.h. der Technologie- und Wissenstransfer in die Gesellschaft und Wirtschaft z.B. über die Ausbildung zukünftiger Gründer:innen und die Förderung von entstehenden Startups. Die Wichtigkeit der Innovationskraft deutscher Hochschulen spiegelt sich zum Beispiel auch in der Verabschiedung des Bayerischen Hochschulinnovationsgesetzes wider, welches explizit die Gründung von Unternehmen aus Hochschulen fördern soll. Die Studie zur Entrepreneurship Performance Deutscher Hochschulen hat das Ziel, die Entrepreneurship Performance aller Hochschulen in Deutschland als Teil der "Third Mission“ zu quantifizieren und zu vergleichen. Damit soll die Studie als Orientierung für Akteure in der Hochschulleitung, in der Hochschulpolitik und Gründer:innen dienen. Methode und Daten - Basierend auf Daten des Handelsregisters über StartupDetector sowie der Plattform Dealroom wurden 27.988 von 2014 bis 2022 in Deutschland gegründete Startups identifiziert (davon wurde für 4.305 Startups mindestens eine Finanzierungsrunde verzeichnet). Auf Basis der Angaben zu Ausbildung und Arbeitserfahrung der Gründer:innen in LinkedIn und Dealroom, der Startup-Webseiten, sowie über Suchmaschinen-Ergebnisse wurden die Startups 296 Deutschen Hochschulen zugeordnet. Die Anzahl der einer Hochschule zugeordneten Startups wurde mit der jeweiligen Studierendenzahl, Mitarbeitendenzahl und dem Etat der Hochschule relativiert (Daten des Statistischen Bundesamts). Wichtigste Ergebnisse - Im absoluten Ranking schneidet die TU München (810 Startups), gefolgt von der TU Berlin (446) und der LMU München (397) am besten ab. In den relativen Rankings führen ausschließlich private Hochschulen wie ESCP (112 Startups / 973 Studierende), HHL (70 / 659) und WHU (136 / 1.878). Die Universität Potsdam bringt die meisten Startups (40% aller Startups) mit mindestens einer Frau im Gründungsteam hervor. Von insgesamt 539 als Deep Tech klassifizierten Startups können 64 der TU München zugeordnet werden, gefolgt von der TU Berlin mit 33. Die meisten (81%) der Gründer:innen bleiben nach ihrem Abschluss in Berlin zur Unternehmensgründung, München hält 64% der Gründer:innen. Im Europäischen Vergleich der gründungsstärksten Hochschulen findet sich die erste Deutsche Hochschule auf Platz 11, im internationalen Vergleich auf Platz 31

Social Media

This anthology brings together cutting-edge research and insightful analysis from experts in linguistics and foreign language education. Applying different methodological approaches to the analysis of social media, researchers from different fields explore how platforms like Twitter, Instagram, and YouTube are reshaping communication, language learning, and teaching methodologies. From the power of hashtags to the role of influencers, this collection reveals the profound impact of digital interactions on modern linguistics and foreign language education. Essential for educators, researchers, and social media enthusiasts, this book offers a fresh perspective on the evolving landscape of Romance languages (French, Spanish and Portuguese) in the digital age

Eddies and an extreme water mass anomaly observed in the eastern south Pacific at the Stratus mooring

In the tropical eastern South Pacific the Stratus Ocean Reference Station (ORS) (∼20°S, 85.5°W) is located in the transition zone between the oxygen minimum zone (OMZ) and the well-oxygenated subtropical gyre. In February/March 2012, extremely anomalous water mass properties were observed in the thermocline at the Stratus ORS. The available eddy oxygen anomaly was −10.5 × 1016 µmol. This anomalous water was contained in an anticyclonic mode-water eddy crossing the mooring site. This eddy was absorbed at that time by an anticyclonic feature located south of the Stratus mooring. This was the largest water property anomaly observed at the mooring during the 13.5 month deployment period. The sea surface height anomaly (SSHA) of the strong mode-water eddy in February/March 2012 was weak, and while the lowest and highest SSHA were related to weak eddies, SSHA is found not to be sufficient to specify the eddy strength for subsurface-intensified eddies. Still, the anticyclonic eddy, and its related water mass characteristics, could be tracked backward in time in SSHA satellite data to a formation region in April 2011 off the Chilean coast. The resulting mean westward propagation velocity was 5.5 cm s−1. This extremely long-lived eddy carried the water characteristics from the near-coastal Chilean water to the open ocean. The water mass stayed isolated during the 11 month travel time due to high rotational speed of about 20 cm s−1 leading to almost zero oxygen in the subsurface layer of the anticyclonic mode-water eddy with indications of high primary production just below the mixed layer

Upstream Statin Therapy and Long-Term Recurrence of Atrial Fibrillation after Cardioversion: A Propensity-Matched Analysis

The relationship of statin therapy with recurrence of atrial fibrillation (AF) after cardioversion (CV) has been evaluated by several investigations, which provided conflicting results and particularly long-term data is scarce. We sought to examine whether upstream statin therapy is associated with long-term recurrence of AF after CV. This was a single-center registry study including consecutive AF patients (n = 454) undergoing CV. Cox regression models were performed to estimate AF recurrence comparing patients with and without statins. In addition, we performed a propensity score matched analysis with a 1:1 ratio. Statins were prescribed to 183 (40.3%) patients. After a median follow-up period of 373 (207–805) days, recurrence of AF was present in 150 (33.0%) patients. Patients receiving statins had a significantly lower rate of AF recurrence (log-rank p < 0.001). In univariate analysis, statin therapy was associated with a significantly reduced rate of AF recurrence (HR 0.333 (95% CI 0.225–0.493), p = 0.001), which remained significant after adjustment (HR 0.238 (95% CI 0.151–0.375), p < 0.001). After propensity score matching treatment with statins resulted in an absolute risk reduction of 27.5% for recurrent AF (21 (18.1%) vs. 53 (45.7%); p < 0.001). Statin therapy was associated with a reduced risk of long-term AF recurrence after successful cardioversion

Impact of cavotricuspid isthmus ablation for typical atrial flutter and heart failure in the elderly—results of a retrospective multi-center study

IntroductionWhile in the CASTLE-AF trial, in patients with atrial fibrillation and heart failure with reduced ejection fraction, interventional therapy using pulmonary vein isolation was associated with outcome improvement, data on cavotricuspid isthmus ablation (CTIA) in atrial flutter (AFL) in the elderly is rare.MethodsWe included 96 patients between 60 and 85 years with typical AFL and heart failure with reduced or mildly reduced ejection fraction (HFrEF/HFmrEF) treated in two medical centers. 48 patients underwent an electrophysiological study with CTIA, whereas 48 patients received rate or rhythm control and guideline-compliant heart failure therapy. Patients were followed up for 2 years, with emphasis on left ventricular ejection fraction (LVEF) over time. Primary endpoints were cardiovascular mortality and hospitalization for cardiac causes.ResultsPatients with CTIA showed a significant increase in LVEF after 1 (p &lt; 0.001) and 2 years (p &lt; 0.001) in contrast to baseline LVEF. Improvement of LVEF in the CTIA group was associated with significantly lower 2-year mortality (p = 0.003). In the multivariate regression analysis, CTIA remained the relevant factor associated with LVEF improvement (HR: 2.845 CI:95% 1.044–7.755; p = 0.041). Elderly patients (≥ 70 years) further benefited from CTIA, since they showed a significantly reduced rehospitalization (p = 0.042) and mortality rate after 2 years (p = 0.013).ConclusionsCTIA in patients with typical AFL and HFrEF/HFmrEF was associated with significant improvement of LVEF and reduced mortality rates after 2 years. Patient age should not be a primary exclusion criterion for CTIA, since patients ≥70 years also seem to benefit from intervention in terms of mortality and hospitalization

Bird migration in space and time: chain migration by Eurasian curlew Numenius arquata arquata along the East Atlantic Flyway

Migration patterns in birds vary in space and time. Spatial patterns include chain, leapfrog and telescopic migration. Temporal patterns such as migration duration, number, and duration of stopovers may vary according to breeding latitude, sex, and season. This study aimed to verify these patterns in a long-distance migrant, the Eurasian curlew Numenius arquata arquata, and to provide a synopsis of spatio-temporal migration patterns in this species of concern throughout the East Atlantic Flyway. We tagged 85 adults with GPS-data loggers in Germany, Poland, France and Estonia between 2013 and 2019. We computed the distance flown, linear loxodromic distance, duration, stopover number, total stopover duration, mean stopover duration, departure time and arrival time for 177 out of 187 tracks. On average (± standard deviation), spring migration occurred from 4 to 14 April (10.2 ± 8.4 days), curlews flew 3.623 ± 1.366 km, and had 5.8 ± 3.6 stopovers, with a duration of 29.4 ± 38.2 h per stopover, while autumn migration occurred from 18 to 29 June (10.9 ± 9.9 days), curlews flew 3.362 ± 1.351 km, and had 5.4 ± 4.0 stopovers, with 31.8 ± 32.3 h per stopover. Curlews displayed chain migration because wintering curlews maintained the latitudinal sequence to their breeding sites. Southern curlews had a longer nesting period due to their earlier arrivals. While spring arrival at breeding sites did not differ between the sexes, in autumn females departed earlier than males. Migration duration and distance, as well as stopover number and duration, showed a significant increase with breeding site latitude but did not differ between the sexes or between spring and autumn migrations, suggesting that curlews took a comparable amount of time migrating during both seasons. The high site faithfulness in curlews suggests that rapid autumn migration allows them to return to defend their winter foraging areas

Search for direct production of charginos and neutralinos in events with three leptons and missing transverse momentum in √s = 7 TeV pp collisions with the ATLAS detector

A search for the direct production of charginos and neutralinos in final states with three electrons or muons and missing transverse momentum is presented. The analysis is based on 4.7 fb−1 of proton–proton collision data delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in three signal regions that are either depleted or enriched in Z-boson decays. Upper limits at 95% confidence level are set in R-parity conserving phenomenological minimal supersymmetric models and in simplified models, significantly extending previous results