First report of ophthalmomyaisis externa in Pakistan

Two individuals presented to the Aga Khan University Opthalmology service with foreign-body sensation, pain and redness in one of their eyes. Slit-lamp biomicroscopy revealed tiny larvae crawling around the conjunctival sac. They were mechanically removed under topical anaesthesia and preserved for light microscopy and photography. Comprehensive liaison was established with the Australian Centre for International Agriculture Research for identification of these larvae. Their morphology characterized them as members of fruit-fly, Oestridae family. At least one of them was positively identified as first instar larva of Oestrus ovis. This report describes the first instance of such infections in Southern Pakistan, as concluded after a Medline search

Evaluation of High Resolution Thermal Imaging to Determine the Effect of Vertebral Fractures on Associated Skin Surface Temperature in Children with Osteogenesis Imperfecta

Vertebral fractures are common in children with osteogenesis imperfecta (OI). Current imaging methods for fracture detection (X-ray and DXA) use ionising radiation. This pilot study explored whether the alteration in blood flow in vertebral fractures results in skin temperature changes that may be detected using high resolution thermal imaging (HRTI) and thus assist diagnosis and monitoring of fractures in OI patients. Eleven participants aged 5-18 years with OI and known vertebral fractures were enrolled. Small metal discs were placed on the skin surface alongside the vertebrae before participants had DXA and X-ray scans and thermal imaging of their backs. Visibility of the discs on the DXA and X-ray scans and thermal images allowed the temperatures of the skin surface above vertebrae without (healthy) and with fractures to be compared to their respective adjacent skin surface regions (Region of Reference, ROR) by calculating the temperature percentage change (TPC). The TPC between the skin temperature over the fractured thoracic vertebrae (n=11) and the ROR was significant (1.44%, p=0.002, 95% confidence). TPC between the skin temperature over healthy thoracic vertebrae and ROR was not (0.97%, p=0.15, 95% confidence). HRTI may provide a novel tool for assisting in detection of vertebral fractures in OI. Keywords: Computerised medical diagnosis, thermal imaging, vertebral fracture detection, osteogenesis imperfecta

Thule Inuit environmental impacts on Kangeq, southwest Greenland

The Leverhulme Trust is thanked for financial support for the project “Footsteps on the Edge of Thule” (Programme Grant F/00 152/Q), directed by Kevin Edwards (University of Aberdeen), Andy Dugmore, Eva Panagiotakopulu (both University of Edinburgh), and Ian Simpson (Stirling University). We are grateful to Andy McMullen, Kirsty Collinge and Ian Simpson for assistance with fieldwork and advice. Gordon Cook is thanked for the provision of radiocarbon dates. Jamie Bowie kindly assisted with the production of diagrams relating to palynological work. The maps and section were drawn by Anastasios Panagiotakopoulos, whose help is warmly acknowledged. Last but not least we are grateful for the helpful comments by the editor and three anonymous reviewers.Peer reviewedPostprin

South Pacific Agriculture: Challenges and Opportunities for ACIAR and its Research Partners

Research and Development/Tech Change/Emerging Technologies,