Supplement_Materials_1 – Supplemental material for Circulating angiopoietin-2 and the risk of mortality in patients with acute respiratory distress syndrome: a systematic review and meta-analysis of 10 prospective cohort studies

Supplemental material, Supplement_Materials_1 for Circulating angiopoietin-2 and the risk of mortality in patients with acute respiratory distress syndrome: a systematic review and meta-analysis of 10 prospective cohort studies by Fengyuan Li, Rulan Yin and Qiang Guo in Therapeutic Advances in Respiratory Disease</p

Reviewer_2_v.1 – Supplemental material for Circulating angiopoietin-2 and the risk of mortality in patients with acute respiratory distress syndrome: a systematic review and meta-analysis of 10 prospective cohort studies

Supplemental material, Reviewer_2_v.1 for Circulating angiopoietin-2 and the risk of mortality in patients with acute respiratory distress syndrome: a systematic review and meta-analysis of 10 prospective cohort studies by Fengyuan Li, Rulan Yin and Qiang Guo in Therapeutic Advances in Respiratory Disease</p

Reviewer_1_v.1 – Supplemental material for Circulating angiopoietin-2 and the risk of mortality in patients with acute respiratory distress syndrome: a systematic review and meta-analysis of 10 prospective cohort studies

Supplemental material, Reviewer_1_v.1 for Circulating angiopoietin-2 and the risk of mortality in patients with acute respiratory distress syndrome: a systematic review and meta-analysis of 10 prospective cohort studies by Fengyuan Li, Rulan Yin and Qiang Guo in Therapeutic Advances in Respiratory Disease</p

PRISMA-2009-Checklist-MS-Word – Supplemental material for Circulating angiopoietin-2 and the risk of mortality in patients with acute respiratory distress syndrome: a systematic review and meta-analysis of 10 prospective cohort studies

Supplemental material, PRISMA-2009-Checklist-MS-Word for Circulating angiopoietin-2 and the risk of mortality in patients with acute respiratory distress syndrome: a systematic review and meta-analysis of 10 prospective cohort studies by Fengyuan Li, Rulan Yin and Qiang Guo in Therapeutic Advances in Respiratory Disease</p

Author_response_1 – Supplemental material for Circulating angiopoietin-2 and the risk of mortality in patients with acute respiratory distress syndrome: a systematic review and meta-analysis of 10 prospective cohort studies

Supplemental material, Author_response_1 for Circulating angiopoietin-2 and the risk of mortality in patients with acute respiratory distress syndrome: a systematic review and meta-analysis of 10 prospective cohort studies by Fengyuan Li, Rulan Yin and Qiang Guo in Therapeutic Advances in Respiratory Disease</p

PRISMA-2009-Flow-Diagram-MS-Word – Supplemental material for Circulating angiopoietin-2 and the risk of mortality in patients with acute respiratory distress syndrome: a systematic review and meta-analysis of 10 prospective cohort studies

Supplemental material, PRISMA-2009-Flow-Diagram-MS-Word for Circulating angiopoietin-2 and the risk of mortality in patients with acute respiratory distress syndrome: a systematic review and meta-analysis of 10 prospective cohort studies by Fengyuan Li, Rulan Yin and Qiang Guo in Therapeutic Advances in Respiratory Disease</p

sj-docx-1-onc-10.1177_11795549221104440 – Supplemental material for Quantification of Tumor Abnormal Proteins in the Diagnosis and Postoperative Prognostic Evaluation of Gastric Cancer

Supplemental material, sj-docx-1-onc-10.1177_11795549221104440 for Quantification of Tumor Abnormal Proteins in the Diagnosis and Postoperative Prognostic Evaluation of Gastric Cancer by Chao Gu, Li Xie, Bowen Li, Lu Zhang, Fengyuan Li, Weizhi Wang, Jiang Su and Zekuan Xu in Clinical Medicine Insights: Oncology</p

sj-docx-2-onc-10.1177_11795549221104440 – Supplemental material for Quantification of Tumor Abnormal Proteins in the Diagnosis and Postoperative Prognostic Evaluation of Gastric Cancer

Supplemental material, sj-docx-2-onc-10.1177_11795549221104440 for Quantification of Tumor Abnormal Proteins in the Diagnosis and Postoperative Prognostic Evaluation of Gastric Cancer by Chao Gu, Li Xie, Bowen Li, Lu Zhang, Fengyuan Li, Weizhi Wang, Jiang Su and Zekuan Xu in Clinical Medicine Insights: Oncology</p

sj-pptx-3-onc-10.1177_11795549221104440 – Supplemental material for Quantification of Tumor Abnormal Proteins in the Diagnosis and Postoperative Prognostic Evaluation of Gastric Cancer

Supplemental material, sj-pptx-3-onc-10.1177_11795549221104440 for Quantification of Tumor Abnormal Proteins in the Diagnosis and Postoperative Prognostic Evaluation of Gastric Cancer by Chao Gu, Li Xie, Bowen Li, Lu Zhang, Fengyuan Li, Weizhi Wang, Jiang Su and Zekuan Xu in Clinical Medicine Insights: Oncology</p

Profiling of Polar Metabolites in Mouse Feces Using Four Analytical Platforms to Study the Effects Of Cathelicidin-Related Antimicrobial Peptide in Alcoholic Liver Disease

Alterations in gut bacterial homeostasis result in changes in intestinal metabolites. To investigate the effects of alcohol on fecal metabolites and the role of cathelicidin-related antimicrobial peptide (CRAMP) in alcoholic liver disease (ALD), CRAMP knockout (KO) and their control wild type (WT) mice were fed a Lieber-DeCarli liquid diet with or without alcohol. Polar metabolites in mouse feces were analyzed by GC × GC-MS and 2DLC-MS, and the concentrations of short chain fatty acids (SCFAs) were measured by GC-MS. A total of 95 and 190 metabolites were detected by GC × GC-MS and 2DLC-MS, respectively. Among the significantly changed metabolites, taurine and nicotinic acid were decreased in WT mice fed alcohol, which were also down-regulated in KO mice fed without alcohol. Interestingly, these two metabolites were increased in KO mice fed alcohol compared to them in WT controls. Additionally, SCFAs were significantly decreased in WT mice fed alcohol and in KO mice fed without alcohol, whereas two branched-chain SCFAs were increased by alcohol treatment in KO mice. In summary, the analytical platforms employed in this study successfully dissected the alterations of polar metabolites and SCFAs in fecal samples, which helped understand the effects of alcohol consumption and CRAMP in intestinal metabolism and alcohol-induced liver injury