7,092 research outputs found

    Flag arrangements and triangulations of products of simplices

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    We investigate the line arrangement that results from intersecting d complete flags in C^n. We give a combinatorial description of the matroid T_{n,d} that keeps track of the linear dependence relations among these lines. We prove that the bases of the matroid T_{n,3} characterize the triangles with holes which can be tiled with unit rhombi. More generally, we provide evidence for a conjectural connection between the matroid T_{n,d}, the triangulations of the product of simplices Delta_{n-1} x \Delta_{d-1}, and the arrangements of d tropical hyperplanes in tropical (n-1)-space. Our work provides a simple and effective criterion to ensure the vanishing of many Schubert structure constants in the flag manifold, and a new perspective on Billey and Vakil's method for computing the non-vanishing ones.Comment: 39 pages, 12 figures, best viewed in colo

    A 3D Role-Playing Game for Abusive Language Annotation

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    Gamification has been applied to many linguistic annotation tasks, as an alternative to crowdsourcing platforms to collect annotated data in an inexpensive way. However, we think that still much has to be explored. Games with a Purpose (GWAPs) tend to lack important elements that we commonly see in commercial games, such as 2D and 3D worlds or a story. Making GWAPs more similar to full-fledged video games in order to involve users more easily and increase dissemination is a demanding yet interesting ground to explore. In this paper we present a 3D role-playing game for abusive language annotation that is currently under development

    An Analysis of Abusive Language Data Collected through a Game with a Purpose

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    In this work we present an analysis of abusive language annotations collected through a 3D video game. With this approach, we are able to involve in the annotation teenagers, i.e. typical targets of cyberbullying, whose data are usually not available for research purposes. Using the game in the framework of educational activities to empower teenagers against online abuse we are able to obtain insights into how teenagers communicate, and what kind of messages they consider more offensive. While players produced interesting annotations and the distributions of classes between players and experts are similar, we obtained a significant number of mismatching judgements between experts and players

    A new diamond biosensor with integrated graphitic microchannels for detecting quantal exocytic events from chromaffin cells

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    The quantal release of catecholamines from neuroendocrine cells is a key mechanism which has been investigated with a broad range of materials and devices, among which carbon-based materials such as carbon fibers, diamond-like carbon, carbon nanotubes and nanocrystalline diamond. In the present work we demonstrate that a MeV-ion-microbeam lithographic technique can be successfully employed for the fabrication of an all-carbon miniaturized cellular bio-sensor based on graphitic micro-channels embedded in a single-crystal diamond matrix. The device was functionally characterized for the in vitro recording of quantal exocytic events from single chromaffin cells, with high sensitivity and signal-to-noise ratio, opening promising perspectives for the realization of monolithic all-carbon cellular biosensors

    Chelating effect in short polymers for the design of bidentate binders of increased affinity and selectivity

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    The design of new strong and selective binders is a key step towards the development of new sensing devices and effective drugs. Both affinity and selectivity can be increased through chelation and here we theoretically explore the possibility of coupling two binders through a flexible linker. We prove the enhanced ability of double binders of keeping their target with a simple model where a polymer composed by hard spheres interacts with a spherical macromolecule, such as a protein, through two sticky spots. By Monte Carlo simulations and thermodynamic integration we show the chelating effect to hold for coupling polymers whose radius of gyration is comparable to size of the chelated particle. We show the binding free energy of flexible double binders to be higher than that of two single binders and to be maximized when the binding sites are at distances comparable to the mean free polymer end-to-end distance. The affinity of two coupled binders is therefore predicted to increase non linearly and in turn, by targeting two non-equivalent binding sites, this will lead to higher selectivity

    From Barriers to Enablers: The Role of Organizational Learning in Transitioning SMEs into the Circular Economy

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    To contribute to small and medium enterprises’ (SMEs) sustainable transition into the circular economy, the study proposes the activation of organizational learning (OL) processes—denoted here as multi-level knowledge creation, transfer, and retention processes—as a key phase in introducing circular business models (CBMs) at SME and supply chain (SC) level. The research employs a mixed-method approach, using the focus group methodology to identify contextual elements impacting on CBM-related OL processes, and a survey-based evaluation to single out the most frequently used OL processes inside Italian construction SMEs. As a main result, a CBM-oriented OL multi-level model offers a fine-grained understanding of contextual elements acting mutually as barriers and drivers for OL processes, as possible OL dynamics among them. The multilevel culture construct—composed of external stakeholders’, SC stakeholders’, and organizational culture—identify the key element to activate CBM-oriented OL processes. Main implications are related to the identification of cultural, structural, regulatory, and process contextual elements across the external, SC, and organizational levels, and their interrelation with applicable intraorganizational and interorganizational learning processes. The proposed model would contribute to an improved implementation of transitioning into the circular economy utilizing sustainable business models in the construction SMEs

    DETECTION OF PESTIVIRUS IN FECAL SAMPLES FROM WILD RUMINANTS BY PCR

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    Ruminant pestiviruses affect wild and domestic ruminants worldwide, causing reproductive disorders and severe economic losses. Usually serological, virological or PCR tests are carried out on serum or blood collected from captured live animals or from organs of dead animals. The aim of this work was to evaluate if fecal samples are suitable for detecting ruminant pestiviruses in wild ruminants. Fecal samples from red deer (Cervus elaphus, n=16) and Appenninic chamois (Rupicapra pyrenaica ornata, n=12) were collected from the environment. Samples were analyzed in a few days and aliquots were stored at 4ºC for 3 months and re-tested. Pooled fecal samples were diluted with PBS, were centrifuged, and the pellet was used for RNA extraction by silica membrane tech-nology. Real Time PCR was carried out to detect Pestivirus spp. Positive samples were used for PCR and sequencing of a 5’UTR sequence. All four pool samples from red deer and 3 out of 4 pool of chamois resulted positive and sequences showed the highest homology with BVDV-1. Positive samples were found also in samples refrigerated for 3 months. To our knowledge, this is the first report of amplification and sequencing of pestiviruses from feces of wild ruminants

    From barriers to enablers: The role of organizational learning in transitioning SMEs into the Circular economy

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    To contribute to small and medium enterprises (SMEs) sustainable transition into the circular economy, the study proposes the activation of organizational learning (OL) processes – denoted here as multi-level knowledge creation, transfer, and retention processes – as a key phase in introducing circular business models (CBMs) at SME and supply chain (SC) level. The research employs a mixed-method approach, using the focus group methodology to identify contextual elements impacting on CBM-related OL processes, and a survey-based evaluation to single out the most frequently used OL processes inside Italian construction SMEs. As main result, a CBM-oriented OL multilevel model offers a fine-grained understanding of contextual elements acting mutually as barriers and drivers for OL processes, as possible OL dynamics among them. The multi-level culture construct – composed of external stakeholders’, SC stakeholders’, and organizational culture – identify the key element to activate CBM-oriented OL processes. Main implications are related to the identification of cultural, structural, regulatory, and process contextual elements across the external, SC, and organizational levels, and their interrelation with applicable intraorganizational and interorganizational learning processes. The proposed model would contribute to an improved implementation of transitioning into the circular economy utilizing sustainable business models in the construction SMEs
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