4 research outputs found
Fast and Protecting-Group-Free Synthesis of (±)-Subincanadine C
The first total synthesis of (±)-subincanadine C has been accomplished in a protecting-group-free fashion. This pentacyclic indole alkaloid was synthesized in six steps from the known intermediate <b>4</b>, featuring Ni(COD)<sub>2</sub>-mediated intramolecular Michael addition as a key transformation
Fast and Protecting-Group-Free Synthesis of (±)-Subincanadine C
The first total synthesis of (±)-subincanadine C has been accomplished in a protecting-group-free fashion. This pentacyclic indole alkaloid was synthesized in six steps from the known intermediate <b>4</b>, featuring Ni(COD)<sub>2</sub>-mediated intramolecular Michael addition as a key transformation
Concise Synthesis of the Oxapentacyclic Core of Cortistatin A
A concise synthetic approach for constructing the oxapentacyclic framework of cortistatin A is described. The synthesis features a furanâoxyallyl [4 + 3] cycloaddition and double-intramolecular aldol reactions. In addition, an interesting core structure was obtained in 11 steps from furan by using our method
Concise Synthesis of the Oxapentacyclic Core of Cortistatin A
A concise synthetic approach for constructing the oxapentacyclic framework of cortistatin A is described. The synthesis features a furanâoxyallyl [4 + 3] cycloaddition and double-intramolecular aldol reactions. In addition, an interesting core structure was obtained in 11 steps from furan by using our method