What Factors Predict High School Graduation in the Los Angeles Unified School District

Analyzes longitudinal data on the educational progress of the district's 2001-02 ninth graders and compares the relative importance of factors affecting graduation rates, including failed classes, transfers, school characteristics, and demographics

Calidad de servicio y la satisfacción del usuario en el área de emergencia de un hospital, Tumbes, 2021.

La presente investigación tuvo la finalidad de determinar la relación que existe entre la calidad de servicio y la satisfacción del usuario en el área de emergencia de un hospital, Tumbes, 2021. El tipo de investigación es descriptivo, correlacional, transversal, con enfoque cuantitativo. Para la recolección de datos se aplicaron dos instrumentos que fueron adaptados y aplicados, se utilizó como técnica la encuesta y como instrumento 2 cuestionarios, ambos en escala de Likert. Tuvo una muestra de 137 usuarios asegurados al Sistema Integral de Salud (SIS) que acuden atenderse. La confiabilidad del instrumento se realizó según el coeficiente de alfa de Cronbach obteniendo como resultado 0.786 y 0,748; por lo tanto, el instrumento según el rango de evaluación es confiable y consistente. Se concluye que si existe un predominio donde el nivel de calidad del servicio que se brinda es regular, un 23% (31 usuarios) consideró que es mala, y apenas el 12.4% de ellos (17 usuarios) indicaron que la calidad del servicio es buena. Para medir la correlación de ambas variables, se utilizó el coeficiente de relación Spearman, arrojando un valor de 0,289 y significativa al nivel 0.01, implica que, si existe una correlación positiva, débil entre ambas variables

Análisis del proyecto de Ley N° 8078-2020-CR ante el incumplimiento de contrato de arrendamiento Rocio

En este trabajo de investigación se manejó como objetivo general determinar la viabilidad del nuevo proceso de desalojo por incumplimiento de contrato dentro del Proyecto de ley N° 8078-2020-CR. Método, inductivo; diseño de investigación, teoría fundamentada; muestra no probabilística; muestra 5 participantes, la técnica empleada fue la entrevista, y como instrumento la guía de entrevista. Se analizó las guías de entrevista en forma individualizada, luego se realizó la integración de los hallazgos y sistematización de la información recaba para por última parte realizar el análisis e interpretación de los resultados de manera inductiva. Finalmente se concluyó que si bien es cierto el proyecto materia del estudio tiene buenas intenciones, el mismo no ha sido desarrollado considerando la realidad de las normativas ya existentes relacionadas al proceso de desalojo, puesto que pretende modificar normas jurídicas que tiene hasta el momento cierto éxito disuasivo y de aplicación para los problemas de inquilinos morosos y precarios, sobre todo el de allanamiento a futuro, el cual es el más utilizado y que mayor rol disuasivo cumple en la práctica, evitando así proceso que se dilaten y no se tengan resultados de recuperación de posesión de los inmuebles

Descripción morfológica y caracterización de daños de Eurysthea sordida (Erichson) (Coleoptera: Cerambycidae) en Alnus acuminata Kunth (Betulaceae) para el valle del Mantaro, región de Junín, Perú

Eurysthea sordida (Erichson) (Coleoptera: Cerambycidae) is a coleopteran of tropical distribution in South America that causes damage of economic importance on Alnus acuminata Kunth in the Mantaro Valley, Junín region, Peru. In the region, there is no complete study of its life cycle and the damage it causes to Alnus acuminata. Therefore, the aim of this research was to study the morphology of the biological stages of E. sordida on A. acuminata, as well as to characterize the damage caused by E sordida. For this, the total length (L) and width (W) of eggs, larvae, pupae and adults of E. sordida were measured, as well as the diameter of the perforations in the bark and sapwood of A. acuminata. Additionally, a complete morphological description of the biological stages of E. sordida to confirm its taxonomic identification was performed. A complete morphological description of the egg, larval and adult pupal stages of E. sordida was carried out and its taxonomic identity was confirmed. Six larval stages were observed with the following parameters, I (2.518 ± 0.421 mm), II (6.228 ± 1.858 mm), III (15.961 ± 2.752 mm), IV (23.048 ± 1.581 mm), V (28.301 ± 1.170 mm), and VI (33.055 ± 1.412 mm). All the specimens of A. acuminata evaluated were attacked by E. sordida individuals, showing slight to very severe damage from the base to the mid-shaft, in the bark, cambium and sapwood. This research is the first report on the biological stages of E. sordida and on the damage to the bark and sapwood of A. acuminata for the Mantaro Valley.Eurysthea sordida (Erichson) (Coleoptera: Cerambycidae) es un coleóptero de distribución tropical en Sudamérica que ocasiona daño de importancia económica en Alnus acuminata Kunth en el valle del Mantaro, región de Junín, Perú. En la región, no hay un estudio completo como el ciclo de vida y el daño que ocasiona a Alnus acuminata. El objetivo de esta investigación es estudiar la morfología de los estadios biológicos de E. sordida recolectados en A. acuminata, así como caracterizar su daño. Para esto, se midió la longitud total (L) y el ancho (A) de huevos, larvas, pupas y adultos de E. sordida, así como el diámetro de las perforaciones en corteza y albura de A. acuminata. Adicionalmente, se realizó la descripción morfológica completa de los estadios biológicos de E. sordida para confirmar su identificación taxonómica y la descripción morfológica completa de los estados de huevo, larva, pupa y adulto de E. sordida. Se observaron seis estadios larvales con los siguientes parámetros, i (2,518 ± 0,421 mm), ii (6,228 ± 1,858 mm), iii (15,961 ± 2,752 mm), iv (23,048 ± 1,581 mm), v (28,301 ± 1,170 mm) y vi (33,055 ± 1,412 mm). Todos los ejemplares de A. acuminata evaluados resultaron atacados por individuos de E. sordida, mostrando daños leves hasta muy severos desde la base hasta el fuste medio, en la corteza, el cámbium y la albura. Esta investigación es el primer reporte de los estadios biológicos de E. sordida y sobre los daños a la corteza y la albura de A. acuminata para el valle del Mantaro

Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain : Large-Scale Epidemiological Study

(1) Aims: To assess the incidence of inflammatory bowel disease (IBD) in Spain, to describe the main epidemiological and clinical characteristics at diagnosis and the evolution of the disease, and to explore the use of drug treatments. (2) Methods: Prospective, population-based nationwide registry. Adult patients diagnosed with IBD-Crohn's disease (CD), ulcerative colitis (UC) or IBD unclassified (IBD-U)-during 2017 in Spain were included and were followed-up for 1 year. (3) Results: We identified 3611 incident cases of IBD diagnosed during 2017 in 108 hospitals covering over 22 million inhabitants. The overall incidence (cases/100,000 person-years) was 16 for IBD, 7.5 for CD, 8 for UC, and 0.5 for IBD-U; 53% of patients were male and median age was 43 years (interquartile range = 31-56 years). During a median 12-month follow-up, 34% of patients were treated with systemic steroids, 25% with immunomodulators, 15% with biologics and 5.6% underwent surgery. The percentage of patients under these treatments was significantly higher in CD than UC and IBD-U. Use of systemic steroids and biologics was significantly higher in hospitals with high resources. In total, 28% of patients were hospitalized (35% CD and 22% UC patients, p < 0.01). (4) Conclusion: The incidence of IBD in Spain is rather high and similar to that reported in Northern Europe. IBD patients require substantial therapeutic resources, which are greater in CD and in hospitals with high resources, and much higher than previously reported. One third of patients are hospitalized in the first year after diagnosis and a relevant proportion undergo surgery

Correction : Chaparro et al. Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study. J. Clin. Med. 2021, 10, 2885

The authors wish to make the following corrections to this paper [...]

Novel genes and sex differences in COVID-19 severity

[EN] Here, we describe the results of a genome-wide study conducted in 11 939 coronavirus disease 2019 (COVID-19) positive cases with an extensive clinical information that were recruited from 34 hospitals across Spain (SCOURGE consortium). In sex-disaggregated genome-wide association studies for COVID-19 hospitalization, genome-wide significance (P < 5 × 10−8) was crossed for variants in 3p21.31 and 21q22.11 loci only among males (P = 1.3 × 10−22 and P = 8.1 × 10−12, respectively), and for variants in 9q21.32 near TLE1 only among females (P = 4.4 × 10−8). In a second phase, results were combined with an independent Spanish cohort (1598 COVID-19 cases and 1068 population controls), revealing in the overall analysis two novel risk loci in 9p13.3 and 19q13.12, with fine-mapping prioritized variants functionally associated with AQP3 (P = 2.7 × 10−8) and ARHGAP33 (P = 1.3 × 10−8), respectively. The meta-analysis of both phases with four European studies stratified by sex from the Host Genetics Initiative (HGI) confirmed the association of the 3p21.31 and 21q22.11 loci predominantly in males and replicated a recently reported variant in 11p13 (ELF5, P = 4.1 × 10−8). Six of the COVID-19 HGI discovered loci were replicated and an HGI-based genetic risk score predicted the severity strata in SCOURGE. We also found more SNP-heritability and larger heritability differences by age (<60 or ≥60 years) among males than among females. Parallel genome-wide screening of inbreeding depression in SCOURGE also showed an effect of homozygosity in COVID-19 hospitalization and severity and this effect was stronger among older males. In summary, new candidate genes for COVID-19 severity and evidence supporting genetic disparities among sexes are provided.S

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

Reflections on Race and Privilege in an Educational Leadership Course

To be effective social justice leaders, school leaders need to gain critical understandings of their positionality and racial privilege and be prepared to engage in difficult conversations with others. This study examines how a peer-to-peer letter exchange assignment in a doctoral course allowed educational leadership doctoral students ( N = 27) to reflect on race and privilege with each other. The findings reveal how students examined racial privilege, positionality, and bias. The authors discuss how this assignment can be used in educational leadership programs to develop and grow the practice of critical reflection for self-examination of privilege.</jats:p