Study flow diagram.

<p>Study flow diagram.</p

General characteristics of the population in study.

<p>Value expressed as mean ± standard deviation (SD) and [range].</p><p>FMI: Fat mass index; FFMI: Fat-free mass index.</p

Comparison of REE and REE/W values obtained by indirect calorimetry and SWA in the two study groups (for details see Methods).

<p><i>*p<0.05</i>, <i>**p<0.001</i>, <i>ns: not significant</i>.</p

Bland & Altman analysis and repeatability coefficients in the two study groups.

<p>Bland & Altman analysis and repeatability coefficients in the two study groups.</p

Results of the exercise performance in the population in study.

<p>Value expressed as mean ± SD.</p>#<p>Test performed breathing oxygen at 3 L/min.</p>†<p>Differences calculated using no-parametric test of Kruskal-Wallis and Wilcoxon test.</p

The relative risks, absolute relative risks and number needed to harm of the events (mortality in the follow-up period at30 days, 6 months, 1 year and 3 years).

<p>The relative risks, absolute relative risks and number needed to harm of the events (mortality in the follow-up period at30 days, 6 months, 1 year and 3 years).</p

Microbiological variables.

<p>Microbiological variables.</p

General characteristics of study cohort.

<p>General characteristics of study cohort.</p

Comparison of EE outcomes recorded during both assisted (<i>Aid</i>) and unassisted (No-<i>Aid</i>) walking in both CRF patients (<i>panel A</i>) and Controls (<i>panel B</i>) (for details see Methods).

<p><i>**p<0.001</i>, <i>ns: not significant</i>.</p

Significant univariate and multivariate Cox regression analyses predicting the probability of death at 1 year.

<p>Significant univariate and multivariate Cox regression analyses predicting the probability of death at 1 year.</p