An overview of various lines in the treatment of warts: Review article

Background: Human papillomavirus (HPV) infection, which can be obtained through direct contact with an infected person or through exposure to the environment, is the most prevalent cause of warts. For example, they can be categorized into common warts, plantar warts, and genital warts based on appearance or location. Common warts have been treated with a variety of invasive and non-invasive methods, both destructive and immunotherapeutic. Cryosurgery, surgical excision, electrocautery, and laser ablation are all examples of destructive therapies. Medical compounds like salicylic acid and trichloroacetic acid are also destructive, as is formaldehyde and 5-flurouracil.Objective: To make an overview of various lines in the treatment of warts.Methods: The databases were searched for articles published in English in 4 data bases [PubMed – Google search - Google scholar- science direct] and Boolean operators (and, or, not) had been used such as [Human papillomavirus, treatment of warts, warts] and in peer-reviewed articles between 2009 and 2021.Conclusion: A wide range of treatments are currently available to help individuals with warts, whether as a single treatment or in combination

Is Presepsin a Reliable Marker of Sepsis Diagnosis in Pediatric Intensive Care Unit?

BACKGROUND: Sepsis is a major challenge in emergency departments and intensive care units (ICUs). Sepsis also mimics or interacts with many other disorders causing high mortality and morbidity. There is no accurate biomarker or test to diagnose or predict sepsis. The treatment of sepsis is often based on the clinician’s experience. AIM: We conducted this study to analyze the serum level of presepsin in pediatric critical patients with SIRS, sepsis, severe sepsis, and septic shock. METHODS: The study included 58 children, 32 septic pediatric patients admitted to the Pediatric ICU (PICU) of Cairo University Teaching Hospital and 26 healthy children who served as a control group. The aim was to estimate the diagnostic accuracy of presepsin in predicting sepsis in PICU. We classified the patients into systemic inflammatory response syndrome, sepsis, severe sepsis, and septic shock according to the international consensus conference criteria. RESULTS: In our study, we detected a positive correlation between C-reactive protein and presepsin levels at day 1 and day 3 of admission and a negative correlation between hemoglobin and presepsin levels at day 1. However, we found no difference in the serum presepsin between the children who had sepsis and the healthy ones (at day 1 [p = 0.430) and at day 3 [p = 0.845]). We also found that serum levels of presepsin were not significantly increased with the increasing severity of sepsis despite the higher median values with increasing sepsis severity. CONCLUSIONS: It was noted that presepsin levels increased in anemic critical patients, whereas presepsin had no role in differentiating the septic critical patients from healthy children. However, its level increased with increasing severity of sepsis grade

Does Reduced Taper Canal Preparation Increase the Load Capacity of Endodontically Treated Teeth?

Objective: The aim of this in-vitro study is to assess and compare the load capacity of teeth with canals prepared using progressive taper versus regressive taper. Methods Twenty-seven extracted mandibular molars were categorized into three equal groups. The negative control group involved teeth that were accessed and restored with composite resin without canal preparation. The regressive canal preparation group used the TruNatomy file system, while the progressive canal preparation group employed the ProTaper Gold system. Subsequently, all samples underwent loading using a universal testing machine until tooth fracture occurred. The force required to fracture each tooth was recorded in Newton. Results: The highest value was found in samples without preparation 1009.68±57.28 N, followed by TN group 979.04±31.16 N, while the lowest value was found in PTG 966.47±17.51N. There was no significant difference between different groups (p=0.118). Conclusion: The root canal taper did not exert a significant influence on the longevity or fracture resistance of the tooth

The Use of Cubic Splines in the Numerical Solution of Fractional Differential Equations

Fractional calculus became a vital tool in describing many phenomena appeared in physics, chemistry as well as engineering fields. Analytical solution of many applications, where the fractional differential equations appear, cannot be established. Therefore, cubic polynomial spline-function-based method combined with shooting method is considered to find approximate solution for a class of fractional boundary value problems (FBVPs). Convergence analysis of the method is considered. Some illustrative examples are presented

Development and implementation of two-stage boost converter for single-phase inverter without transformer for PV systems

This paper offers a two-stage boost converter for a single-phase inverter without transformer for PV systems. Each stage of the converter is separately controlled by a pulse width modulated signal. A Simulink model of the converter using efficient voltage control topology is developed. The proposed circuit performance characteristics are explained and the obtained simulation results are confirmed through the applied experiments. Moreover, this paper has examined the control circuit of a single-phase inverter that delivers a pure sine wave with an output voltage that has the identical value and frequency as a grid voltage. A microcontroller supported an innovative technology is utilized to come up with a sine wave with fewer harmonics, much less price and an easier outline. A sinusoidal pulse width modulation (SPWM) technique is used by a microcontroller. The developed inverter integrated with the two-stage boost converter has improved the output waveform quality and controlled the dead time as it decreased to 63 µs compared to 180 µs in conventional methods. The system design is reproduced in Proteus and PSIM Software to analyze its operation principle that is confirmed practically

Transcultural aspects of cannabis use : a descriptive overview of cannabis use across cultures

Purpose of Review: This narrative review summarises cultural aspects of cannabis use across different (sub)cultures, nations, and gender, racial, and ethnic groups. Specifically, we aimed to overview historical and traditional contexts of cannabis use and physical and mental health-related correlates, as well as emerging cannabis-related policies and their impacts on medicinal and recreational use of cannabis. In addition, we discuss how cultural factors may affect cannabis use behaviours and sociocultural underpinnings of cannabis use disorder trajectories. Recent Findings: Cannabis is the most widely cultivated, trafficked, and used illicit drug worldwide, although cannabis is being legalised in many jurisdictions. More than 4% of individuals globally have used cannabis in the last year. Being traditionally used for religious and ritualistic purposes, today cannabis use is interwoven with, and influenced by, social, legal, economic, and cultural environments which often differ across countries and cultures. Notably, empirical data on distinct aspects of cannabis use are lacking in selected underrepresented countries, geographical regions, and minority groups. Summary: Emerging global policies and legislative frameworks related to cannabis use have impacted the prevalence and attitudes toward cannabis in different subcultures, but not all in the same way. Therefore, it remains to be elucidated how and why distinct cultures differ in terms of cannabis use. In order to understand complex and bidirectional relationships between cannabis use and cultures, we recommend the use of cross-cultural frameworks for the study of cannabis use and its consequences and to inform vulnerable people, clinical practitioners, and legislators from different world regions.Publisher PDFPeer reviewe

Investigation of Crystal Structure, Electrical and Magnetic Properties of Spinel Mn-Cd Ferrite Nanoparticles

Cd1 − xMnxFe2O4 (x = 0, 0.25, 0.5, 0.75, 1) spinel ferrite nanoparticle samples were synthesized using a flash auto-combustion technique and analyzed using X-ray diffraction (XRD), scanning electron microscopy (SEM), and Fourier-transform infrared spectroscopy (FTIR). The inspection of dielectric and magnetic properties of the prepared ferrites was carried out by using broadband dielectric spectroscopy (BDS) and vibration sample magnetometer (VSM) measurements, respectively. X-ray diffraction analysis verified the formation of the main cubic phase with space group Fd3m and a decrease in lattice constants with the increase in Mn-content. FTIR study revealed the two characteristic absorption bands of spinel ferrites and their dependence on Mn-content was investigated and explained. Elastic moduli, bulk modulus, rigidity modulus, Young modulus, and calculated Debye temperature have been studied and found to decrease with the increase in Mn-content. SEM analysis revealed nanoparticles agglomeration of uniform grains with increasing in the average grain size as Mn-content increased. The VSM measurements showed an increase in saturation magnetization accompanied by a decrease in coercivity as Mn-content increased. Dielectric investigations showed very high values of permittivity and dielectric loss at lower frequencies (between 105 and 106 @ 0.1 Hz according to the manganese content) reflecting the combination of exchange of electrons between ferrous and ferric ions and ions’ transport. The ac-conductivity showed a plateau that yields the dc-conductivity at lower frequencies followed by a characteristic frequency at which it tends out to follow a power law. The relation between these two parameters confirms the empirical BNN-relation. © 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature