40 research outputs found

    The Certification of the Mass Fraction of Chloramphenicol in Pork Meat - Certified Reference Material ERM®-BB130

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    This report describes the preparation of the pork meat matrix reference material ERM-BB130 and the certification of the content (mass fraction) of chloramphenicol. The preparation and processing of the material, homogeneity and stability studies, and the characterisation are described hereafter and the results are discussed. Uncertainties were calculated in compliance with ISO Guide 98-3, Guide to the Expression of Uncertainty in Measurement (GUM) [1] and include uncertainties due to possible heterogeneity, instability, and characterisation.JRC.DG.D.2-Reference material

    Certification of the Mass Concentrations of Ammonium, Chloride, Fluoride, Magnesium, Nitrate, Ortho-Phosphate, Sulfate and of pH and Conductivity in Simulated Rainwater - Certified Reference Material ERM®-CA408

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    This report presents the preparation and certification of the simulated rainwater certified reference material ERM-CA408. All the steps required for the production of this water-matrix certified reference material are described in detail, from the preparation of the simulated rainwater until the characterization exercise that lead to the final assignment of the certified values, following ISO Guide 34:2009 [1] and ISO Guide 35:2006 [2]. Homogeneity and stability of the water material were investigated with dedicated studies and the certification campaign for the material characterisation was based on an inter-comparison among several experienced laboratories. IRMM organised and coordinated all the phases of this project including evaluation of data. The certified values were calculated as the unweighted mean of the laboratory means of the accepted sets of results for each parameter, see below. Uncertainties were calculated in compliance with the Guide to the Expression of Uncertainty in Measurement (GUM, ISO/IEC Guide 98-3:2008) [3]. The stated expanded uncertainties include contributions from characterisation, homogeneity and stability.JRC.DG.D.2-Reference material

    Certification of the Mass Concentrations of Arsenic, Cadmium, Iron, Lead, Manganese, Mercury and Nickel in Groundwater - Certified Reference Material ERM®-CA615

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    This report presents the preparation and certification of groundwater reference material ERM-CA615. All steps required for the production of this water-matrix reference material are described in detail, from the sampling of natural groundwater to the characterisation exercise that lead to the final assignment of the certified values, following ISO Guide 34:2009 [1] and ISO Guide 35:2006 [2]. Homogeneity and stability of the water material were investigated with dedicated studies and the certification campaign for the material characterisation was based on an inter-comparison involving several experienced laboratories. IRMM organised and coordinated all phases of this project and carried out the evaluation of data. The certified values were calculated as the unweighted mean of the laboratory means of the accepted sets of results for each parameter, as seen below. Uncertainties were calculated in compliance with the Guide to the Expression of Uncertainty in Measurement (GUM, ISO/IEC Guide 98-3:2008) [3]. The stated expanded uncertainties include contributions from characterisation, homogeneity and long-term stability.JRC.DG.D.2-Reference material

    The Certification of the Mass Fractions of Proximates and Essential Elements in Rye Flour and Wheat Flour -- Certified Reference Materials ERM®-BC381 and ERM®-BC382

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    This report describes the preparation of the rye flour matrix reference materials ERM®BC381 and ERM®-BC382, respectively, and the certification of the contents (mass fractions) of four proximates and four essential elements. All results are expressed as a mass fraction on a dry mass basis. The preparation and processing of the materials, homogeneity studies, stability studies and characterisation are described hereafter and the results are discussed. Uncertainties were calculated in compliance with Guide to the expression of Uncertainty in Measurement (GUM) and include uncertainties due to possible heterogeneity, instability and from characterisation.JRC.DDG.D.2-Reference material

    Report of the Ninth Interlaboratory Comparison Organised by the European Union Reference Laboratory for Heavy Metals in Feed and Food - IMEP-109: Total Cadmium, Lead, Arsenic and Mercury as well as Methylmercury and Inorganic Arsenic in Seafood

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    The Institute for Reference Materials and Measurements (IRMM) of the Joint Research Centre (JRC), a Directorate General of the European Commission, operates the European Union Reference Laboratory for Heavy Metals in Feed and Food (EU-RL-HM). One of its core tasks is to organise interlaboratory comparisons (ILCs) among appointed National Reference Laboratories (NRLs). This report presents the results of the ninth proficiency test (PT) of the EU-RL-HM which focused on the determination of total cadmium, lead, arsenic and mercury as well as methylmercury and inorganic arsenic in seafood. The test material used in this exercise was the Certified Reference Material (CRM) DOLT-4, dogfish liver of the National Research Council of Canada (CNRC). The material was relabelled to prevent recognition by the participants and was dispatched the second half of May 2010. Each participant received one bottle containing approximately 20 g of test material. Thirty-eight laboratories from 27 countries registered to the exercise of which 38 reported results for total Cd, 36 for total Pb, 33 for total As, 36 for total Hg, five for methylmercury and 10 for iAs. The assigned values for total Cd, Pb, As, Hg and methylmercury are the certified values taken from the DOLT-4 certificate. An attempt was made to establish an assigned value for inorganic As (iAs) using the results provided by a group of five laboratories expert in the field, following a similar approach to that used in IMEP-1071, a PT on total and inorganic arsenic in rice. Contrary to what was observed in IMEP-107, the results obtained by the expert laboratories for iAs was method dependent, therefore no assigned value could be established. The uncertainties of the assigned values, uref, were taken directly from the CRM certificate as provided by the producer for total Cd, Pb, As, Hg and methylmercury. Participants were invited to report the uncertainty of their measurements. This was done by the majority of the laboratories taking part in this exercise. Laboratory results were rated with z- and ┬┐-scores (zeta-scores) in accordance with ISO 135282. Since the concentration of iAs seems to be method dependent according to the results obtained by the expert laboratories, no scoring was provided to the laboratories that submitted results for iAs. The standard deviation for proficiency assessment (also called target standard deviation) was fixed to 15% by the advisory board of this ILC, on the basis of the outcome of previous ILCs organised by the EURL-HM and on the state-of-the-art in this field of analysis. Between 80 and 97.5 % of the laboratories performed satisfactory for total Cd, As, Hg and methylmercury. Regarding total Pb, 70 % of the laboratories scored satisfactory.JRC.DG.D.6-Food Safety and Qualit

    The certification of the mass fractions of total arsenic, dimethylarsinic acid and the sum of arsenite and arsenate in rice: ERM-BC211

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    This report describes the production of ERM-BC211, a powdered rice material certified for the mass fractions of total arsenic, dimethylarsinic acid and the sum of arsenite and arsenate. The material has been produced following ISO Guide 34:2009. The starting material, which had been checked for its arsenic species was purchased and supplied by the University of Aberdeen. The rice was milled, sieved, dried, homogenised, filled in vials and sterilised. Between unit-inhomogeneity was quantified and stability during dispatch and storage was assessed in accordance with ISO Guide 35:2006 . Within-unit inhomogeneity was quantified to determine the minimum sample intake. The material was characterised by an intercomparison among laboratories of demonstrated competence and adhering to ISO/IEC 17025. Technically invalid results were removed but no outlier was eliminated on statistical grounds only. Uncertainties of the certified values were estimated in compliance with ISO/IEC Guide 98-3, Guide to the Expression of Uncertainty in Measurement (GUM) and they include contributions from possible between-unit inhomogeneity, instability and characterisation. The material is intended for quality control and assessment of method performance. Moreover, it can be used for validation purposes and trueness determination. The CRM is available in glass bottles containing 10 g of dried rice powder closed under argon atmosphere. The minimum amount of sample to be used for total arsenic and dimethylarsinic acid is 50 mg. The minimum amount of sample to be used for the sum of arsenite and arsenate is 100 mg. The CRM has been accepted as European Reference Material (ERM) after peer evaluation by the partners of the European Reference Materials consortium.JRC.D.2-Standards for Innovation and sustainable Developmen

    IMEP-30: Total Arsenic, Cadmium, Lead, and Mercury, as well as Methylmercury and Inorganic Arsenic in Seafood - Interlaboratory Comparison Report

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    This report presents the results of an ILC which focussed on the determination of total As, Cd, Pb , and Hg, as well as methylmercury and inorganic arsenic in seafood. The test material used in this exercise was the Certified Reference Material (CRM) DOLT-4, dogfish liver of the National Research Council of Canada (NRC). Each participant received one bottle containing approximately 20 g of test material. Fifty-seven laboratories from 29 countries registered to the exercise and all of them reported results. The assigned values and their associate uncertainties for total As, Cd, Pb, Hg and Methylmercury are the certified values taken from the DOLT-4 certificate. An attempt was made to establish an assigned value for inorganic As (iAs) using the results provided by a group of five laboratories expert in the field. Unfortunately, contrary to what was expected, the results obtained by the expert laboratories for iAs showed a large spread and no assigned value could be established.JRC.DG.D.6-Food Safety and Qualit

    Report of the Seventh Interlaboratory Comparison organized by the European Union - Reference Laboratory for Heavy Metals in Feed and Food. IMEP-107: Total and Inorganic As in Rice.

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    The Institute for Reference Materials and Measurands (IRMM) of the Joint Research Centre (JRC), a Directorate-General of the European Commission, operates the European Union-Reference Laboratory for Heavy Metals in Feed and Food (EU-RL-HM). Two of its core tasks are to provide advice to the Directorate General for Health and Consumers (DG Sanco) on scientific matters and to organise interlaboratory comparisons (ILC) among appointed National Reference Laboratories (NRLs). This report represents the results of the seventh ILC of the EU-RL-HM (former CRL-HM) which focused on the determination of total and inorganic As in rice. The test item used in this exercise is rice purchased in a local supermarket and was provided by the University of Aberdeen. The test item was processed, bottled and labelled at IRMM and dispatched to the participants the first half of December 2009. Each participant received one bottle containing approximately 20 g of test item. Participation in this exercise was not limited to the NRLs but was open to laboratories from all around the world, to be able to judge the state-of-the-art of the determination of total and, exercise, of which 98 reported results for total As and 30 for inorganic As. Twenty-nine of the participants were NRLs of the EU-RL-HM network, 8 out of which reported values for inorganic As. The assigned values for IMEP-107 were provided by a group of laboratories expert in the field: seven for total As and six for inorganic As. The uncertainties of the respective assigned values, uref, were derived from the standard deviation of the means provided by the experts, propagated with a contribution for homogeneity, ubb, and stability, ust. Laboratory results were rated with z-and ┬┐-scores (zeta-scores) in accordance with ISO 13528. The standard deviation for proficiency assessment (also called target standard deviation) was fixed to 15% by the advisory board of this ILC, on the basis of the outcome of previous ILCs organised by the EU-RL-HL and on the state-of-the-art in this field of analysis. Around 75% of the participants performed satisfactory for total and inorganic As.JRC.DDG.D.6-Food Safety and Qualit

    Report of the Tenth Interlaboratory Comparison Organised by the European Union Reference Laboratory for Heavy Metals in Feed and Food - IMEP-110: Total Arsenic, Cadmium, Mercury and Lead in Vegetable Food

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    The Institute for Reference Materials and Measurements (IRMM) of the Joint Research Centre (JRC) a Directorate-General of the European Commission operates the European Union Reference Laboratory for Heavy Metals in Feed and Food (EU-RL-HM). One of its core tasks is to organise interlaboratory comparisons (ILCs) among appointed National Reference Laboratories (NRLs). This report presents the results of the tenth ILC of the EU-RL-HM which focused on the determination of total arsenic, cadmium, mercury and lead in vegetable food. The test material used in this exercise was the Standard Reference Material SRM 1570a, spinach leaves of the National Institute of Standards and Technology (NIST). The material was rebottled and relabelled to prevent recognition by the participants and was dispatched at the beginning of June. Each participant received one bottle containing approximately 15 g of test material. Thirty-five laboratories from 24 countries registered to the exercise of which 35 reported results for total Cd and total Pb, 32 for total As and 31 for total Hg. The assigned values for total As, Cd and Hg are the certified values taken from the SRM 1570a certificate. For total Pb, the "information value" provided by NIST in the SRM certificate was used as assigned value. The uncertainties of the assigned values (uref) for total As, Cd and Hg, were taken directly from the CRM certificate as provided by the producer. No uref is provided by NIST for the total Pb concentration because the total Pb content is only provided as "information value". Participants were invited to report the uncertainty of their measurements. This was done by the majority of the laboratories taking part in this exercise. Laboratories' results were rated with z- and zeta-scores for total As, Cd, and Hg in accordance to ISO 13528. No zeta-scores were given for total Pb because uref was not known for that measurand. The standard deviation for proficiency assessment (also called target standard deviation) was fixed to 15 % for all the measurands by the advisory board of this ILC, on the basis of the outcome of previous ILCs organised by the EU-RL-HM and on the state-of-the-art in this field of analysis. More than 80 % of the participants performed satisfactory for total Cd and Hg. Around 70 % of the participants obtained a satisfactory z-score for total arsenic with a relatively high number (8 laboratories) of participants having overestimated the total content of arsenic in the test material. When looking at the zeta-scores, 60 to 65 % of the reported results were satisfactory when the associated uncertainties are taken into account.JRC.DG.D.6-Food Safety and Qualit

    IMEP-111: Total Cadmium, Lead, Arsenic, Mercury and Copper and Extractable Cadmium and Lead in Mineral Feed - Report of the Eleventh Interlaboratory Comparison Organised by the European Union Reference Laboratory for Heavy Metals in Feed and Food

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    The Institute for Reference Materials and Measurements (IRMM) of the Joint Research Centre, a Directorate-General of the European Commission, operates the European Union Reference Laboratory for Heavy Metals in Feed and Food (EU-RL-HM). One of its core tasks is to organize interlaboratory comparisons (ILCs) among appointed National Reference Laboratories. This report presents the results of the eleventh proficiency test (PT) of the EU-RL-HM which focused on the determination of total Cd, Pb, As, Hg and Cu and extractable Cd and Pb in mineral feed according to Directive 2002/32/EC of the European Parliament and of the Council on undesirable substances in animal feed. The test material used in this exercise was the Certified Reference Material (CRM) BCR-032, Moroccan phosphate rock. The material was relabelled to prevent identification by the participants and was dispatched the second half of October 2010. Each participant received one bottle containing approximately 100 g of test material. Thirty-one laboratories from 26 countries registered to the exercise of which 28 reported results for total Cd and total Pb, 25 for total Hg and total Cu, 23 for total As and for extractable Cd and extractable Pb. The assigned values (Xref) for total Cd, As and Cu are the indicative values taken from the BCR-032 certificate. The assigned values (Xref) for total Pb, total Hg and for extractable Cd and Pb were provided by IRMM using isotope dilution-inductively coupled plasma-mass spectrometry (ID-ICP-MS). For total Cd, As, Hg and Cu and for extractable Cd, the uncertainty of the assigned values (uref) was calculated by combining the uncertainty of the characterization (uchar) and a contribution for between-bottle homogeneity (ubb) (which was calculated from the certification report). For total and extractable Pb the number of replicates performed to establish the assigned value was higher (11 replicates) than for the other measurands (6 replicates). Since the aliquots were taken from different bottles, it was assumed that uchar included a contribution for the homogeneity. For total Cd, As and Cu, uchar were taken from the CRM certificate as indicated by the producer. For extractable Cd the same uchar as for total Cd was used. For total Pb and Hg and for extractable Pb, uchar was calculated according to the ISO Guide for the Expression of Uncertainty in Measurement (GUM). Participants were invited to report the uncertainties of their measurements. This was done by the majority of the laboratories taking part in this exercise.JRC.DG.D.6-Food Safety and Qualit
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