Supplementary Data from Chondroitinase ABC I–Mediated Enhancement of Oncolytic Virus Spread and Antitumor Efficacy

Supplementary Figures S1-S3.</p

Supplementary video from Extracellular Vesicles from High-Grade Glioma Exchange Diverse Pro-oncogenic Signals That Maintain Intratumoral Heterogeneity

M and P GSCs display distinct intra-spherical organization in vitro. Representative time lapse movie</p

Supplementary TABLE 2 from Extracellular Vesicles from High-Grade Glioma Exchange Diverse Pro-oncogenic Signals That Maintain Intratumoral Heterogeneity

Genes coding for protein sets that vary coherently between GSC subtypes within 89- protein signature, were retrieved from TCGA GBM dataset and identified by subtype prediction.</p

Supplementary Figure 3 from Extracellular Vesicles from High-Grade Glioma Exchange Diverse Pro-oncogenic Signals That Maintain Intratumoral Heterogeneity

Supplementary Figure 3 related to Figure 3. Presence of P GSC supports pro-oncogenic traits of M GSCs in vivo</p

Supplementary Figure Legend from Extracellular Vesicles from High-Grade Glioma Exchange Diverse Pro-oncogenic Signals That Maintain Intratumoral Heterogeneity

Figure Legend to all supplementary data</p

Supplementary Figure 1 from Extracellular Vesicles from High-Grade Glioma Exchange Diverse Pro-oncogenic Signals That Maintain Intratumoral Heterogeneity

Supplementary Figure 1 related to Figure 1. Analysis of GSC EV proteome heterogeneity reveals coherent molecular modules.</p

Supplementary Figure 2 from Extracellular Vesicles from High-Grade Glioma Exchange Diverse Pro-oncogenic Signals That Maintain Intratumoral Heterogeneity

Supplementary Figure 2 related to Figure 2. Presence of EVM supports pro-oncogenic traits of P GSCs in vitro.</p

Figures S1 to S8 from Development of a Function-Blocking Antibody Against Fibulin-3 as a Targeted Reagent for Glioblastoma

Figure S1: Generation of mAb428.2 antibody; Figure S2: Affinity of mAb428.2 for fibulin-3; Figure S3: mAb428.2 binds to cell-surface and interstitial fibulin-3; Figure S4: mAb428.2 does not cause acute toxicity; Figure S5: Locally-delivered mAb428.2 targets fibulin-3 signaling and tumor growth; Figure S6: IV-delivered mAb428.2 inhibits tumor growth; Figure S7: Effects of mAb428.2 against intracranial tumors; Figure S8: Biodistribution of mAb428.2 in naïve and tumor-bearing mice.</p

Legends of Figs S1 to S8 unmarked from Development of a Function-Blocking Antibody Against Fibulin-3 as a Targeted Reagent for Glioblastoma

Legends of Figs S1 to S8, unmarked version</p

Supplementary Methods from Extracellular Vesicles from High-Grade Glioma Exchange Diverse Pro-oncogenic Signals That Maintain Intratumoral Heterogeneity

Supplementary material and methods</p