20 research outputs found

    3-D models of T1-weighted MR-images with overlay of HARDI+CS-(red), and DTI-(green)-based tractography of the optic radiation presented as hulled fiber objects.

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    <p>A+A′: Case presentation (case 7): Case of a large temporo-mesial GBM of a 45 year-old male patient, showing the marked differences of HARDI+CS-, and DTI-based fiber objects in case of a large, high-grade tumor. A: axial oblique view. A′: Axial oblique view. Tumor manually segmented in yellow. B+B′: Case presentation (case 6): 35 year-old male patient with small diffuse astrocytoma. Less remarkable differences of tractography results in case of this smaller, low-grade tumor. B: Left sagittal oblique view. B′: Axial oblique view. Tumor manually segmented in yellow.</p

    Validation on medical data.

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    <p>Axial slices of MRI data in upward order with the Broca and Wernicke speech areas (yellow), fMRI activations (white and yellow) and ventral pathways along the inferior fronto-occipital fasciculus (IFOF) reconstructed by global search (GS) (green). Images show patient (female, 36 years old) with language lateralized to the left hemisphere and with a left temporal astrocytoma (WHO grade II, shown in red).</p

    Trimming of fibers with closest point pairs at fiber endings.

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    <p><i>Top</i>: Trimming of overlapping endings according to <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0050132#pone.0050132-Ding1" target="_blank">[47]</a>. Segments between end points and intermediate points are removed (end points to dashed lines). <i>Bottom</i>: Trimming of diverging fibers is avoided with the new approach (end points to dotted lines).</p

    Barplots showing the average fractional anisotropy () of the resulting fiber tracts of each compared pair of methods for the AF (left) and IFOF (right) in the patient and control group.

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    <p>The numbers N of matching fiber tract pairs are provided in parenthesis. For an explanation of the reduced numbers see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0050132#pone-0050132-g005" target="_blank">Figure 5</a>.</p