General approach for preparing sandwich-structured metal sulfide@reduced graphene oxide as highly reversible Li-ion battery anode

<p>A general method for preparing sandwiched nanostructures consisting of reduced graphene oxide (rGO) and metal sulfides is presented. As a demonstrating example, the sandwiched MoS₂@rGO nanocomposites show a good electrochemical performance including a high reversible capability of 1345 mAh g⁻¹ at 0.5 A g⁻¹ over 400 cycles, and a superior rate performance. Moreover, this method has been verified to fabricate a large set of transition metal sulfides- and double metal sulfides-based rGO composites such as CoS@rGO, NiS@rGO, NiCo₂S₄@rGO, and CuCo₂S₄@rGO, enabling the preparing approach presented here applicable for many possible anode and cathode chemistries.</p> <p><b>Impact statement</b></p> <p>A general strategy for the fabrication of sandwiched nanostructures consisting of reduced graphene oxide (rGO) and metal sulfides for highly reversible Li-ion battery anode has been developed.</p

L'Auto-vélo : automobilisme, cyclisme, athlétisme, yachting, aérostation, escrime, hippisme / dir. Henri Desgranges

22 mars 19301930/03/22 (A31,N10689)

Additional file 5: of Identification and integrated analysis of differentially expressed lncRNAs and circRNAs reveal the potential ceRNA networks during PDLSC osteogenic differentiation

lncRNA_differential expression.xlsx Differentially expressed lncRNAs identified by RNA-seq (XLSX 87 kb

Table1_Genetically predicted circulating levels of cytokines and the risk of oral cavity and pharyngeal cancer: a bidirectional mendelian-randomization study.XLSX

Background: Epidemiological research has established associations between various inflammatory cytokines and the occurrence of oral cancer and oropharyngeal cancer (OCPC). We performed a Mendelian randomization (MR) analysis to systematically investigate the causal relationship between inflammatory cytokines and OCPC.Methods: We performed a bidirectional two-sample MR analysis using OCPC from 12 studies (6,034 cases and 6,585 controls) and genome-wide association study (GWAS) results for 41 serum cytokines from 8,293 Finns, respectively. Inverse variance weighting was used as the primary MR method and four additional MR methods (MR Egger, Weighted median, Simple mode, Weighted mode) were used to examine genetic associations between inflammatory traits and OCPC, and Cochran’s Q test, MR-Egger intercept, leave-one-out analysis, funnel plot, and multivariate MR (MVMR) analysis were used to assess the MR results.Results: The results suggested a potential association between high gene expression of Macrophage inflammatory protein-1α (MIP1α/CCL3) and an increased risk of OCPC (Odds Ratio (OR): 1.71, 95% Confidence Interval (CI): 1.09–2.68, p = 0.019). Increasing the expression levels of the interleukin-7 (IL-7) gene by 1 standard deviation reduced the risk of OCPC (OR: 0.64, 95%CI: 0.48–0.86, p = 0.003). In addition, multivariate Mendelian randomization analysis also showed the same results (MIP1α/CCL3, OR: 1.002, 95% CI: 0.919–1.092, p = 0.044; IL-7, OR: 0.997, 95% CI: 0.994–0.999, p = 0.011). Conversely, there was a positive correlation between genetic susceptibility to OCPC and an increase in Interleukin-4 (IL-4) (OR: 1.04, 95%CI: 1.00–1.08, p = 0.027).Conclusion: Our study systematically assessed the association between inflammatory cytokines and the risk of OCPC. We identified two upstream regulatory factors (IL-7 and CCL3) and one downstream effector factor (IL-4) that were associated with OCPC, offering potential avenues for the development of novel treatments.</p

Image1_Genetically predicted circulating levels of cytokines and the risk of oral cavity and pharyngeal cancer: a bidirectional mendelian-randomization study.pdf

Background: Epidemiological research has established associations between various inflammatory cytokines and the occurrence of oral cancer and oropharyngeal cancer (OCPC). We performed a Mendelian randomization (MR) analysis to systematically investigate the causal relationship between inflammatory cytokines and OCPC.Methods: We performed a bidirectional two-sample MR analysis using OCPC from 12 studies (6,034 cases and 6,585 controls) and genome-wide association study (GWAS) results for 41 serum cytokines from 8,293 Finns, respectively. Inverse variance weighting was used as the primary MR method and four additional MR methods (MR Egger, Weighted median, Simple mode, Weighted mode) were used to examine genetic associations between inflammatory traits and OCPC, and Cochran’s Q test, MR-Egger intercept, leave-one-out analysis, funnel plot, and multivariate MR (MVMR) analysis were used to assess the MR results.Results: The results suggested a potential association between high gene expression of Macrophage inflammatory protein-1α (MIP1α/CCL3) and an increased risk of OCPC (Odds Ratio (OR): 1.71, 95% Confidence Interval (CI): 1.09–2.68, p = 0.019). Increasing the expression levels of the interleukin-7 (IL-7) gene by 1 standard deviation reduced the risk of OCPC (OR: 0.64, 95%CI: 0.48–0.86, p = 0.003). In addition, multivariate Mendelian randomization analysis also showed the same results (MIP1α/CCL3, OR: 1.002, 95% CI: 0.919–1.092, p = 0.044; IL-7, OR: 0.997, 95% CI: 0.994–0.999, p = 0.011). Conversely, there was a positive correlation between genetic susceptibility to OCPC and an increase in Interleukin-4 (IL-4) (OR: 1.04, 95%CI: 1.00–1.08, p = 0.027).Conclusion: Our study systematically assessed the association between inflammatory cytokines and the risk of OCPC. We identified two upstream regulatory factors (IL-7 and CCL3) and one downstream effector factor (IL-4) that were associated with OCPC, offering potential avenues for the development of novel treatments.</p

Lewis and Brønsted Acid Synergistic Catalysis for Efficient Synthesis of Hydroxylamine over Heteroatom Zeolites

Environmental and efficient synthesis of NH2OH is challenging. Herein, we have provided a route for efficient NH2OH formation by NH3 oxidation via the synergistic catalysis of Lewis acid sites of the framework Ti (Ti LAS) and Brønsted acid sites of the framework Al (Al BAS) in Ti–Al-MOR zeolites. Ti LAS was the active center for formation of transition-state NH2OH, while Al BAS could provide the proton H to convert transition-state NH2OH absorbed on Ti LAS to a [NH3OH]+ species. Protonation effect would not only promote the catalytic cycle process resulting from accelerating the desorption of transition-state NH2OH, but also improve the stability of NH2OH, being less prone to oxidative decomposition. In this work, we presented the synergistic catalysis between LAS and BAS over Ti-containing heteroatom zeolites to accelerate the catalytic cycle, which provided an environmental and efficient method for NH2OH formation

Definition of landmarks used in this study.

<p>Definition of landmarks used in this study.</p

Patients of TB group were instructed to wear TB appliance.

<p>A) The front view. B) The right view. C) The left view.</p

The pre- (T1) and post-treatment (T2) data of TB patients was registered.

<p><b>A</b>) Point registration with the most protruding points on the anterior cranial base. <b>B</b>) STL registration of T1 and T2 models in front. <b>C</b>) STL registration of T1 and T2 models in lateral. <b>D</b>) The upper airway models of T1 and T2 data. <b>E</b>) STL registration of the upper airway of T1 and T2 data. <b>F</b>) The upper airway model of the control data. <b>G</b>) STL registration of the mandible of T1 and T2 data in the sagittal view. <b>H</b>) STL registration of the mandible of T1 and T2 data in the axial view. <b>I</b>) Displacement of the mandible during TB treatment was measured.</p

3D model of the upper airway was reconstructed.

<p><b>A</b>) The upper airway was subdivided into three parts by two planes perpendicular to the sagittal plane and each region was highlighted in different colors. The landmarks used for defining the planes were: PNS, posterior nasal spine; SE, the superior border of the epiglottis. <b>B</b>) Each region of the upper airway was reconstructed respectively. The nasopharynx is the region from the top of the upper airway to PNS. Oropharynx region is between PNS and SE, and the hypopharynx is from SE to the level of the third cervical vertebra (C3).</p