Synthesis and Structural Characterization of Homoleptic 1,2,4-Diazaphospholide Alkaline Earth Metal Complexes

The alkaline earth metal complexes [(η²-3,5-<i>t</i>Bu₂dp)­(μ-Mg)­(η¹:η¹-3,5-<i>t</i>Bu₂dp)]₂ (<b>2</b>), {[(η²-3,5-<i>t</i>Bu₂dp)­(μ-η²:η⁵-3,5-<i>t</i>Bu₂dp)­(μ-η²:η¹-3,5-<i>t</i>Bu₂dp)­Ca]₂(μ-Ca)} (<b>3</b>), [Sr­(3,5-<i>t</i>Bu₂dp)₂]_<i>m</i> (<b>4</b>), [Ba­(3,5-<i>t</i>Bu₂dp)₂)]_<i>n</i> (<b>5</b>), and [η¹-{H­(3,5-<i>t</i>Bu₂dp)}₂Ca­(η²-3,5-<i>t</i>Bu₂dp)₂] (<b>6</b>), bearing bulky 1,2,4-diazaphospholide ligands [3,5-<i>t</i>Bu₂dp]⁻ ([3,5-<i>t</i>Bu₂dp]⁻ = 3,5-di<i>-tert</i>-butyl-1,2,4-diazaphospholide), were prepared. The structures of magnesium and calcium 1,2,4-diazaphospholide complexes represent homoleptic 1,2,4-diazaphospholide alkaline earth metal oligomers with a novel array of metal–ligand binding modes

Additional file 1: Table S1. of Characterization of a novel splicing mutation in UNC13D gene through amplicon sequencing: a case report on HLH

Functional alteration prediction of two splicing mutations in UNC13D gene with HSF3. (PDF 233 kb