Inquiry Tickets: Values, Pursuit, and Underdetermination

We offer a new account of the role of values in theory choice that captures a temporal dimension to the values themselves. We argue that non-epistemic values sometimes serve as “inquiry tickets,” justifying scientists’ pursuit of certain questions in the short run, while the answers to those questions mitigate transient underdetermination in the long run. Our account of inquiry tickets shows that the role of non-epistemic values need not be restricted to belief or acceptance in order to be relevant to hypothesis choice: the relevance of non-epistemic values to a particular cognitive attitude with respect to h vary over time

Wishful Intelligibility, Black Boxes, and Epidemiological Explanation

Epidemiological explanation often has a ``black box" character, meaning the intermediate steps between cause and effect are unknown. Filling in black boxes is thought to improve causal inferences by making them intelligible. I argue that adding information about intermediate causes to a black box explanation is an unreliable guide to pragmatic intelligibility because it may mislead us about the stability of a cause. I diagnose a problem that I call wishful intelligibility, which occurs when scientists misjudge the limitations of certain features of an explanation. Wishful intelligibility gives us a new reason to prefer black box explanations in some contexts

Sins of Inquiry: How to Criticize Scientific Pursuits

Criticism is a staple of the scientific enterprise and of the social epistemology of science. Philosophical discussions of criticism have traditionally focused on its roles in relation to objectivity, confirmation, and theory choice. However, attention to criticism and to criticizability should also inform our thinking about scientific pursuits: the allocation of resources with the aim of developing scientific tools and ideas. In this paper, we offer an account of scientific pursuitworthiness which takes criticizability as its starting point. We call this the apokritic model of pursuit. Its core ideas are that pursuits are practices governed by norms for asking and answering questions, and that criticism arises from the breach of these norms. We illustrate and advertise our approach using examples from institutional grant review, neuroscience, and sociology. We show that the apokritic model can unify several indices of criticizability, that it can account for the importance of criticizing pursuits in scientific practice, and that it can offer ameliorative advice to erstwhile pursuers

Inquiry Tickets: Values, Pursuit, and Underdetermination

We offer a new account of the role of values in theory choice that captures a temporal dimension to the values themselves. We argue that non-epistemic values sometimes serve as “inquiry tickets,” justifying scientists’ pursuit of certain questions in the short run, while the answers to those questions mitigate transient underdetermination in the long run. Our account of inquiry tickets shows that the role of non-epistemic values need not be restricted to belief or acceptance in order to be relevant to hypothesis choice: the relevance of non-epistemic values to a particular cognitive attitude with respect to h vary over time

Inquiry Tickets: Values, Pursuit, and Underdetermination

We offer a new account of the role of values in theory choice that captures a temporal dimension to the values themselves. We argue that non-epistemic values sometimes serve as “inquiry tickets,” justifying scientists’ pursuit of certain questions in the short run, while the answers to those questions mitigate transient underdetermination in the long run. Our account of inquiry tickets shows that the role of non-epistemic values need not be restricted to belief or acceptance in order to be relevant to hypothesis choice: the relevance of non-epistemic values to a particular cognitive attitude with respect to h vary over time

Why “sex as a biological variable” conflicts with precision medicine initiatives

Policies that require male-female sex comparisons in all areas of biomedical research conflict with the goal of improving health outcomes through context-sensitive individualization of medical care. Sex, like race, requires a rigorous, contextual approach in precision medicine. A “sex contextualist” approach to gender-inclusive medicine better aligns with this aim

Why “sex as a biological variable” conflicts with precision medicine initiatives

Policies that require male-female sex comparisons in all areas of biomedical research conflict with the goal of improving health outcomes through context-sensitive individualization of medical care. Sex, like race, requires a rigorous, contextual approach in precision medicine. A “sex contextualist” approach to gender-inclusive medicine better aligns with this aim

Making a ‘sex-difference fact’:Ambien dosing at the interface of policy, regulation, women’s health, and biology

The U.S. Food and Drug Administration’s (FDA) 2013 decision to lower recommended Ambien dosing for women has been widely cited as a hallmark example of the importance of sex differences in biomedicine. Using regulatory documents, scientific publications, and media coverage, this article analyzes the making of this highly influential and mobile ‘sex-difference fact’. As we show, the FDA’s decision was a contingent outcome of the drug approval process. Attending to how a contested sex-difference fact came to anchor elite women’s health advocacy, this article excavates the role of regulatory processes, advocacy groups, and the media in producing perceptions of scientific agreement while foreclosing ongoing debate, ultimately enabling the stabilization of a binary, biological sex-difference fact and the distancing of this fact from its conditions of construction

Cooperative Epistemic Trustworthiness

Extant accounts of trust in science focus on reconciling scientific and public value judgments, but neglect the challenge of learning audience values. I argue that for scientific experts to be epistemically trustworthy, they should adopt a cooperative approach to learning about the values of their audience. A cooperative approach, in which expert and non-expert inquirers iteratively refine value judgments, better achieves important second-order epistemic dimensions of trustworthiness. Whereas some epistemologists take trustworthiness to be a precondition for the objectivity of science, I suggest that strong objectivity in the standpoint theoretic sense is sometimes a prerequisite for trustworthiness itself

Cooperative Epistemic Trustworthiness

Extant accounts of trust in science focus on reconciling scientific and public value judgments, but neglect the challenge of learning audience values. I argue that for scientific experts to be epistemically trustworthy, they should adopt a cooperative approach to learning about the values of their audience. A cooperative approach, in which expert and non-expert inquirers iteratively refine value judgments, better achieves important second-order epistemic dimensions of trustworthiness. Whereas some epistemologists take trustworthiness to be a precondition for the objectivity of science, I suggest that strong objectivity in the standpoint theoretic sense is sometimes a prerequisite for trustworthiness itself