Garbage collection auto-tuning for Java MapReduce on Multi-Cores

MapReduce has been widely accepted as a simple programming pattern that can form the basis for efficient, large-scale, distributed data processing. The success of the MapReduce pattern has led to a variety of implementations for different computational scenarios. In this paper we present MRJ, a MapReduce Java framework for multi-core architectures. We evaluate its scalability on a four-core, hyperthreaded Intel Core i7 processor, using a set of standard MapReduce benchmarks. We investigate the significant impact that Java runtime garbage collection has on the performance and scalability of MRJ. We propose the use of memory management auto-tuning techniques based on machine learning. With our auto-tuning approach, we are able to achieve MRJ performance within 10% of optimal on 75% of our benchmark tests

Decay of accelerated protons and the existence of the Fulling-Davies-Unruh effect

We investigate the weak decay of uniformly {\em accelerated protons} in the context of {\em standard} Quantum Field Theory. Because the mean {\em proper} lifetime of a particle is a scalar, the same value for this observable must be obtained in the inertial and coaccelerated frames. We are only able to achieve this equality by considering the Fulling-Davies-Unruh effect. This reflects the fact that the Fulling-Davies-Unruh effect is mandatory for the consistency of Quantum Field Theory. There is no question about its existence provided one accepts the validity of standard Quantum Field Theory in flat spacetime.Comment: 4 pages (revtex), 1 figure, to appear in Phys. Rev. Let

Judicial Settlement of the account of Mary R. Goelet, George G. DeWitt and Robert Goelet

https://digitalcommons.salve.edu/goelet-miscellaneous/1003/thumbnail.jp

Energy-momentum tensor of a Casimir apparatus in a weak gravitational field: scalar case

Recent work in the literature had evaluated the energy-momentum tensor of a Casimir apparatus in a weak gravitational field, for an electromagnetic field subject to perfect conductor boundary conditions on parallel plates. The Casimir apparatus was then predicted to experience a tiny push in the upwards direction, and the regularized energy-momentum tensor was found to have a trace anomaly. The latter, unexpected property made it compelling to assess what happens in a simpler case. For this purpose, the present paper studies a free, real massless scalar field subject to homogeneous Dirichlet conditions on the parallel plates. Working to first order in the constant gravity acceleration, the resulting regularized and renormalized energy-momentum tensor is found to be covariantly conserved, while the trace anomaly vanishes if the massless scalar field is conformally coupled to gravity. Conformal coupling also ensures a finite Casimir energy and finite values of the pressure upon parallel plates.Comment: 14 pages, Revtex

Beyond Environmental Regulatory Fragmentation: Signs of Integration in the Case of the Great Lakes Basin

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/72007/1/j.1468-0491.1995.tb00197.x.pd

Challenging the Science Curriculum Paradigm: TeachingPrimary Children Atomic-Molecular Theory

Solutions to global issues demand the involvement of scientists, yet concern exists about retention rates in science as students pass through school into University. Young children are curious about science, yet are considered incapable of grappling with abstract and microscopic concepts such as atoms, sub-atomic particles, molecules and DNA. School curricula for primary (elementary) aged children reflect this by their limitation to examining only what phenomena are without providing any explanatory frameworks for how or why they occur. This research challenges the assumption that atomic-molecular theory is too difficult for young children, examining new ways of introducing atomic theory to 9 year olds and seeks to verify their efficacy in producing genuine learning in the participants. Early results in three cases in different schools indicate these novel methods fostered further interest in science, allowed diverse children to engage and learn aspects of atomic theory, and satisfied the children’s desire for intellectual challenge. Learning exceeded expectations as demonstrated in the post-interview findings. Learning was also remarkably robust, as demonstrated in two schools eight weeks after the intervention, and in one school, one year after their first exposure to ideas about atoms, elements and molecules

Kaposi's Sarcoma Associated Herpes Virus (KSHV) Induced COX-2: A Key Factor in Latency, Inflammation, Angiogenesis, Cell Survival and Invasion

Kaposi's sarcoma (KS), an enigmatic endothelial cell vascular neoplasm, is characterized by the proliferation of spindle shaped endothelial cells, inflammatory cytokines (ICs), growth factors (GFs) and angiogenic factors. KSHV is etiologically linked to KS and expresses its latent genes in KS lesion endothelial cells. Primary infection of human micro vascular endothelial cells (HMVEC-d) results in the establishment of latent infection and reprogramming of host genes, and cyclooxygenase-2 (COX-2) is one of the highly up-regulated genes. Our previous study suggested a role for COX-2 in the establishment and maintenance of KSHV latency. Here, we examined the role of COX-2 in the induction of ICs, GFs, angiogenesis and invasive events occurring during KSHV de novo infection of endothelial cells. A significant amount of COX-2 was detected in KS tissue sections. Telomerase-immortalized human umbilical vein endothelial cells supporting KSHV stable latency (TIVE-LTC) expressed elevated levels of functional COX-2 and microsomal PGE2 synthase (m-PGES), and secreted the predominant eicosanoid inflammatory metabolite PGE2. Infected HMVEC-d and TIVE-LTC cells secreted a variety of ICs, GFs, angiogenic factors and matrix metalloproteinases (MMPs), which were significantly abrogated by COX-2 inhibition either by chemical inhibitors or by siRNA. The ability of these factors to induce tube formation of uninfected endothelial cells was also inhibited. PGE2, secreted early during KSHV infection, profoundly increased the adhesion of uninfected endothelial cells to fibronectin by activating the small G protein Rac1. COX-2 inhibition considerably reduced KSHV latent ORF73 gene expression and survival of TIVE-LTC cells. Collectively, these studies underscore the pivotal role of KSHV induced COX-2/PGE2 in creating KS lesion like microenvironment during de novo infection. Since COX-2 plays multiple roles in KSHV latent gene expression, which themselves are powerful mediators of cytokine induction, anti-apoptosis, cell survival and viral genome maintainence, effective inhibition of COX-2 via well-characterized clinically approved COX-2 inhibitors could potentially be used in treatment to control latent KSHV infection and ameliorate KS

Building consensus in strategic decision-making : system dynamics as a group support system

Contains fulltext : 28724.pdf (publisher's version ) (Open Access)System dynamics was originally founded as a method for modeling and simulating the behavior of industrial systems. In recent years it is increasingly employed as a Group Support System for strategic decision-making groups. The model is constructed in direct interaction with a management team, and the procedure is generally referred to as group model-building. The model can be conceptual (qualitative) or a full-blown (quantitative) computer simulation model. In this article, a case is described in which a qualitative system dynamics model was built to support strategic decision making in a Dutch government agency. Since people from different departments held strongly opposite viewpoints on the strategy, the agency had discussed its strategic problem for more than a year, but was obviously not able to reach consensus. The application of group model-building was successful in integrating opposite points of view, as well as in fostering consensus and creating commitment. The purpose of the article is twofold: first, to illustrate the process of group model-building with system dynamics; second, to evaluate why it was successful. Evaluation results reveal the importance of both systemic thinking through model-building and the role of the facilitator in catalyzing the strategic decision-making process

Update on the methods of the U.S. Preventive Services Task Force: insufficient evidence

The U.S. Preventive Services Task Force (USPSTF) seeks to provide reliable and accurate evidence-based recommendations to primary care clinicians. However, clinicians indicate frustration with the lack of guidance provided by the USPSTF when the evidence is insufficient to make a recommendation. This article describes a new USPSTF plan to commission its Evidence-based Practice Centers to collect information in 4 domains pertinent to clinical decisions about prevention and to report this information routinely. The 4 domains are potential preventable burden, potential harm of the intervention, costs (both monetary and opportunity), and current practice. The process and rationale used to select these domains are presented, along with examples of how clinicians might use the information to guide clinical decision making when evidence is insufficient