SONOCHEMICAL DEGRADATION OF CARBON TETRACHLORIDE IN AQUEOUS SOLUTION AT TWO FREQUENCIES : 200KHZ AND 600KHZ, 200W ACOUSTIC POWER

Joint Research on Environmental Science and Technology for the Eart

STUDY ON APPLICABILITY OF THE CONTACT OXIDATION PROCESS IN REMOVAL OF ORGANIC POLLUTANTS FROM TEXTILE WASTEWATER

Joint Research on Environmental Science and Technology for the Eart

Does it match? Analyzing self-reported online dermatology match data to Charting Outcomes in the Match

Dermatology is arguably the most competitive residency (81.6% match rate for United States allopathic seniors) with significantly more applicants than available positions. To objectify this process, the National Residency Match Program (NRMP) has produced bi-annual Charting Outcomes in Match (COM) datasets, which aggregate data from the prior two application cycles and tabulate statistics to aid applicants. In parallel, online forums provide medical trainees with vast amounts of information, including residency application insights. Reddit medical school subforum compiles annual spreadsheets of anonymous, individualized applicant data to aid future applicants. We compared this data to NRMP data to show that although the data means are similar (e.g. Step 1), the Reddit dermatology spreadsheet collects more data and the individualized nature aids applicants in a personalized way unlike the mean aggregate data in NRMP. Under univariate analysis, Alpha Omega Alpha status, overall publications, and dermatology-specific publications are associated with interview invitation rates. Although limitations of the study include small data size and reporting bias, this is the first of its kind to our knowledge to compare these two often-used tools to aid dermatology applicants. Future endeavors should expand anonymous data reporting and use the data to carry out more extensive studies to investigate factors influencing the application process

The contribution of free radicals in paracetamol degradation by UV/NaClO

UV/Chlorine is an emerging advanced oxidation process which forms several reactive species including •OH, •Cl, •OCl. This study investigated the contribution of three main free radicals: •OH, •Cl, •OCl on Paracetamol degradation under different conditions. Benzoic acid (BA), Nitro benzene (NB) and DMOB were used as probe compounds. The second rate constant of •OH, •Cl, •OCl with PRC were determined: 4.19 (±0.15) ×109 M-1s-1; 3.71 1010 M-1s-1; 3.532×109 M-1s-1, respectively. The formation of free radicals depends on pH. In particular, at pH 5: the contribution of •OH and     (-•OCl, •Cl) are 45 %, 41 %, respectively, at pH 8.5, the contribution of free radicals increases up to 63 %. Keywords. Paracetamol, UV/Chlorine process, reactive species

Adaptive dynamic programing based optimal control for a robot manipulator

In this paper, the optimal control problem of a nonlinear robot manipulator in absence of holonomic constraint force based on the point of view of adaptive dynamic programming (ADP) is presented. To begin with, the manipulator was intervened by exact linearization. Then the framework of ADP and Robust Integral of the Sign of the Error (RISE) was developed. The ADP algorithm employs Neural Network technique to tune simultaneously the actor-critic network to approximate the control policy and the cost function, respectively. The convergence of weight as well as position tracking control problem was considered by theoretical analysis. Finally, the numerical example is considered to illustrate the effectiveness of proposed control design.

Adaptive dynamic programming algorithm for uncertain nonlinear switched systems

This paper studies an approximate dynamic programming (ADP) strategy of a group of nonlinear switched systems, where the external disturbances are considered. The neural network (NN) technique is regarded to estimate the unknown part of actor as well as critic to deal with the corresponding nominal system. The training technique is simul-taneously carried out based on the solution of minimizing the square error Hamilton function. The closed system’s tracking error is analyzed to converge to an attraction region of origin point with the uniformly ultimately bounded (UUB) description. The simulation results are implemented to determine the effectiveness of the ADP based controller

Sensitive detection of circulating methylated SEPT9 in hepatocellular carcinoma patients using a novel quantitative PCR assay †

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide. Early detection is crucial, yet reliable biomarkers are limited. Methylated SEPT9 (mSEPT9) has emerged as a promising biomarker for HCC. Building upon previous ExBP technology, we enhanced the semi-nested realtime PCR assay by integrating TaqMan probes, enabling quantitative detection of mSEPT9 in plasma samples of HCC patients. The assay was validated using synthetic DNA standards and plasma samples from 49 HCC patients, 20 chronic liver disease (CLD) patients, and 32 healthy donors (HDs). Our assay demonstrated sensitivity in detecting methylation ratios as low as 1 : 100 000. The assay showed a strong linear correlation between Ct values and methylation levels over four orders of magnitude (R2 = 0.96178), indicating robust quantification. Clinically, the assay revealed significant differences in ΔCt values between HCC patients (median ΔCt = 19.55) and controls (CLD: 29.32 and HDs: 26.19, p < 0.005). ROC analysis for HCC vs. controls yielded an AUC of 0.729, with 77.55% sensitivity and 59.62% specificity at the optimal cutoff (≤25.98). Notably, the assay identified 72.73% of HCC cases with AFP levels below 20 ng mL−1, underscoring its potential in detecting AFP-negative cases. These findings suggest that the novel mSEPT9 assay is a sensitive and specific tool for early HCC detection, offering prognostic value for clinical monitoring

Sensitive Organophosphorus and Carbamate Pesticides Biosensor Based on Acetylcholinesterase and CdZnSe/ZnS Ternary Alloy Quantum Dots

This report presents the results of ternary alloy quantum dots (TQDs) manufacturing and its superior optical properties to fabricate the biosensor for pesticide detection. The explanation for the changes in PL intensity based on the change of electronic charges that alters the pH value of the surrounding environment, and the types of interaction on the surface of CdZnSe/ZnS TQDs were discussed. We show the decomposition process of the indicator (ATCh) with the catalysis from acetylcholinesterase enzyme (AChE) that inhibited by organophosphorus and carbamate pesticides including Trichlorfon (TF), Cypermethrin (CH), Abamectin (AT), and Carbosulfan (CS) with concentrations from 0.05 ppm to 10 ppm

Mechanism to Detect Pesticide Residues in Tealeaves Based on CdZnSe/ZnS Ternary Alloy Quantum Dots

In this report, we present the optical properties of the biosensors fabricated from CdZnSe/ZnS quantum dots. The optical properties such as absorption and emission of the ternary quantum dots before and after coupling with the protein molecules like streptavidine (SA) and acetylcholinesterase enzymes (AChE), to form a biosensor structure, will be presented. In particular, the changes in luminescence intensity according to the pH value of the solution environment containing biosensor have been considered, before and after the presence of pesticides. The changes in luminescence intensity of the biosensor after the presence of pesticide over time from 2 seconds to 26 minutes were also surveyed. We have been carried out the tests to determine the trace amounts of commercial pesticides like Motox 5EC, containing 5% cypermethrin and Tungatin 10 EC, containing 10% abamectin, on the real samples of tealeaves. Some characteristics of the relationship between composition, structure, and special optical properties of ternary alloy quantum dots will also be presented. These studies open up the potential applications of  ternary quantum dots for agricultural production

A High-Quality Genome Assembly of Striped Catfish (Pangasianodon hypophthalmus) Based on Highly Accurate Long-Read HiFi Sequencing Data

The HiFi sequencing technology yields highly accurate long-read data with accuracies greater than 99.9% that can be used to improve results for complex applications such as genome assembly. Our study presents a high-quality chromosome-scale genome assembly of striped catfish (Pangasianodon hypophthalmus), a commercially important species cultured mainly in Vietnam, integrating HiFi reads and Hi-C data. A 788.4 Mb genome containing 381 scaffolds with an N50 length of 21.8 Mb has been obtained from HiFi reads. These scaffolds have been further ordered and clustered into 30 chromosome groups, ranging from 1.4 to 57.6 Mb, based on Hi-C data. The present updated assembly has a contig N50 of 14.7 Mb, representing a 245-fold and 4.2-fold improvement over the previous Illumina and Illumina-Nanopore-Hi-C based version, respectively. In addition, the proportion of repeat elements and BUSCO genes identified in our genome is remarkably higher than in the two previously released striped catfish genomes. These results highlight the power of using HiFi reads to assemble the highly repetitive regions and to improve the quality of genome assembly. The updated, high-quality genome assembled in this work will provide a valuable genomic resource for future population genetics, conservation biology and selective breeding studies of striped catfish