RBC aggregation dynamics in autologous plasma and serum studied with double-channel optical tweezers

Red blood cells aggregating and disaggregating forces were measured in the autologous plasma and serum using the double-channeled optical tweezers. A significant, three-fold decrease of the both forces was observed in the serum compared to the plasma. The results of this study help to better assess the RBC aggregation mechanism

Scorecard for monitoring language policy and its approbation on the example of the Russian Federation’s regions

El artículo está dedicado a cuestiones de estado y desarrollo de la política lingüística a nivel regional. Teniendo en cuenta la estructura federal del país y el alto grado de diversidad lingüística e interétnica en las regiones de la Federación de Rusia, existen diferencias significativas en los aspectos organizativos y sustantivos de la política lingüística, los principios básicos y las direcciones formuladas a nivel federal. El artículo presenta los fundamentos metodológicos y la implementación práctica de la evaluación de actividades de las autoridades de los temas de la Federación de Rusia para preservar y apoyar los idiomas nativos de los pueblos de la Federación de Rusia. The article is devoted to issues of the state and development of language policy at the regional level. Taking into consideration the country’s federal structure and the high degree of linguistic and interethnic diversity in the Russian Federation’s regions, there are significant differences in the organizational and substantive aspects of the language policy, the basic principles and directions formulated at the federal level. The article presents the methodological foundations and practical implementation of the activities assessment of the authorities of the Russian Federation’ subjects in preserving and supporting the native languages of the peoples of the Russian Federation

Digital Economy in the Post-COVID Period: Changes, Communication Processes and Development Prospects

Topicality: Without a doubt, the COVID-19 pandemic has made significant changes in consumer behavior, further strengthening the transition of the global system from the classical economy to the digital economy. In the context of the pandemic, consumer behavior has become even more digital: initially it was associated with health safety standards to limit social face-to-face contacts, and later consumers could not imagine their life without online aggregators of food delivery, documents, clothing, etc. The goal of the research: to conduct a theoretical review of the features of the development of the digital economy and communication strategies of management before the COVID-19 pandemic and already in the post-COVID-19 period. Methods of research: comparative analysis, methods of generalization and classification, historical analysis. Results of the research: the study made it possible to form a theoretical overview of the scientific material and ideas for preparing for a statistical analysis of the global macroeconomic indicators of the digital economy. Practical application: The chapter will be useful for the relevant government agencies (in Russia, for instance, the Ministry of Digital Development) for developing practical recommendations on a broader digitalization of management systems

LHCb upgrade software and computing : technical design report

This document reports the Research and Development activities that are carried out in the software and computing domains in view of the upgrade of the LHCb experiment. The implementation of a full software trigger implies major changes in the core software framework, in the event data model, and in the reconstruction algorithms. The increase of the data volumes for both real and simulated datasets requires a corresponding scaling of the distributed computing infrastructure. An implementation plan in both domains is presented, together with a risk assessment analysis

Physics case for an LHCb Upgrade II - Opportunities in flavour physics, and beyond, in the HL-LHC era

The LHCb Upgrade II will fully exploit the flavour-physics opportunities of the HL-LHC, and study additional physics topics that take advantage of the forward acceptance of the LHCb spectrometer. The LHCb Upgrade I will begin operation in 2020. Consolidation will occur, and modest enhancements of the Upgrade I detector will be installed, in Long Shutdown 3 of the LHC (2025) and these are discussed here. The main Upgrade II detector will be installed in long shutdown 4 of the LHC (2030) and will build on the strengths of the current LHCb experiment and the Upgrade I. It will operate at a luminosity up to 2×1034 cm−2s−1, ten times that of the Upgrade I detector. New detector components will improve the intrinsic performance of the experiment in certain key areas. An Expression Of Interest proposing Upgrade II was submitted in February 2017. The physics case for the Upgrade II is presented here in more depth. CP-violating phases will be measured with precisions unattainable at any other envisaged facility. The experiment will probe b → sl+l−and b → dl+l− transitions in both muon and electron decays in modes not accessible at Upgrade I. Minimal flavour violation will be tested with a precision measurement of the ratio of B(B0 → μ+μ−)/B(Bs → μ+μ−). Probing charm CP violation at the 10−5 level may result in its long sought discovery. Major advances in hadron spectroscopy will be possible, which will be powerful probes of low energy QCD. Upgrade II potentially will have the highest sensitivity of all the LHC experiments on the Higgs to charm-quark couplings. Generically, the new physics mass scale probed, for fixed couplings, will almost double compared with the pre-HL-LHC era; this extended reach for flavour physics is similar to that which would be achieved by the HE-LHC proposal for the energy frontier

Study of the B−→Λc+Λˉc−K−B^{-} \to \Lambda_{c}^{+} \bar{\Lambda}_{c}^{-} K^{-} decay

The decay $B^{-} \to \Lambda_{c}^{+} \bar{\Lambda}_{c}^{-} K^{-}$ is studied in proton-proton collisions at a center-of-mass energy of $\sqrt{s}=13$ TeV using data corresponding to an integrated luminosity of 5 $\mathrm{fb}^{-1}$ collected by the LHCb experiment. In the $\Lambda_{c}^+ K^{-}$ system, the $\Xi_{c}(2930)^{0}$ state observed at the BaBar and Belle experiments is resolved into two narrower states, $\Xi_{c}(2923)^{0}$ and $\Xi_{c}(2939)^{0}$, whose masses and widths are measured to be $$m(\Xi_{c}(2923)^{0}) = 2924.5 \pm 0.4 \pm 1.1 \,\mathrm{MeV}, \\ m(\Xi_{c}(2939)^{0}) = 2938.5 \pm 0.9 \pm 2.3 \,\mathrm{MeV}, \\ \Gamma(\Xi_{c}(2923)^{0}) = \phantom{000}4.8 \pm 0.9 \pm 1.5 \,\mathrm{MeV},\\ \Gamma(\Xi_{c}(2939)^{0}) = \phantom{00}11.0 \pm 1.9 \pm 7.5 \,\mathrm{MeV},$$ where the first uncertainties are statistical and the second systematic. The results are consistent with a previous LHCb measurement using a prompt $\Lambda_{c}^{+} K^{-}$ sample. Evidence of a new $\Xi_{c}(2880)^{0}$ state is found with a local significance of $3.8\,\sigma$, whose mass and width are measured to be $2881.8 \pm 3.1 \pm 8.5\,\mathrm{MeV}$ and $12.4 \pm 5.3 \pm 5.8 \,\mathrm{MeV}$, respectively. In addition, evidence of a new decay mode $\Xi_{c}(2790)^{0} \to \Lambda_{c}^{+} K^{-}$ is found with a significance of $3.7\,\sigma$. The relative branching fraction of $B^{-} \to \Lambda_{c}^{+} \bar{\Lambda}_{c}^{-} K^{-}$ with respect to the $B^{-} \to D^{+} D^{-} K^{-}$ decay is measured to be $2.36 \pm 0.11 \pm 0.22 \pm 0.25$, where the first uncertainty is statistical, the second systematic and the third originates from the branching fractions of charm hadron decays.Comment: All figures and tables, along with any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-028.html (LHCb public pages

Multidifferential study of identified charged hadron distributions in ZZ-tagged jets in proton-proton collisions at s=\sqrt{s}=13 TeV

Jet fragmentation functions are measured for the first time in proton-proton collisions for charged pions, kaons, and protons within jets recoiling against a $Z$ boson. The charged-hadron distributions are studied longitudinally and transversely to the jet direction for jets with transverse momentum 20 $< p_{\textrm{T}} < 100$ GeV and in the pseudorapidity range $2.5 < \eta < 4$. The data sample was collected with the LHCb experiment at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 1.64 fb$^{-1}$. Triple differential distributions as a function of the hadron longitudinal momentum fraction, hadron transverse momentum, and jet transverse momentum are also measured for the first time. This helps constrain transverse-momentum-dependent fragmentation functions. Differences in the shapes and magnitudes of the measured distributions for the different hadron species provide insights into the hadronization process for jets predominantly initiated by light quarks.Comment: All figures and tables, along with machine-readable versions and any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-013.html (LHCb public pages

Measurement of the ratios of branching fractions R(D∗)\mathcal{R}(D^{*}) and R(D0)\mathcal{R}(D^{0})

The ratios of branching fractions $\mathcal{R}(D^{*})\equiv\mathcal{B}(\bar{B}\to D^{*}\tau^{-}\bar{\nu}_{\tau})/\mathcal{B}(\bar{B}\to D^{*}\mu^{-}\bar{\nu}_{\mu})$ and $\mathcal{R}(D^{0})\equiv\mathcal{B}(B^{-}\to D^{0}\tau^{-}\bar{\nu}_{\tau})/\mathcal{B}(B^{-}\to D^{0}\mu^{-}\bar{\nu}_{\mu})$ are measured, assuming isospin symmetry, using a sample of proton-proton collision data corresponding to 3.0 fb${ }^{-1}$ of integrated luminosity recorded by the LHCb experiment during 2011 and 2012. The tau lepton is identified in the decay mode $\tau^{-}\to\mu^{-}\nu_{\tau}\bar{\nu}_{\mu}$. The measured values are $\mathcal{R}(D^{*})=0.281\pm0.018\pm0.024$ and $\mathcal{R}(D^{0})=0.441\pm0.060\pm0.066$, where the first uncertainty is statistical and the second is systematic. The correlation between these measurements is $\rho=-0.43$. Results are consistent with the current average of these quantities and are at a combined 1.9 standard deviations from the predictions based on lepton flavor universality in the Standard Model.Comment: All figures and tables, along with any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-039.html (LHCb public pages

Features of Assessment and Formation of the Aeration Regime of Residential Development on the Sloping Lands of the Russian Arctic

The urban development of areas in the Arctic zone of the Russian Federation is a relevant and important task to be tackled by contemporary urban planners. This focus is largely explained by the development of the Northern Sea Route (NSR) and its port cities. Last but not least, to develop these cities means to ensure a comfortable living environment for local residents and visiting specialists. However, given the harsh climate in the Arctic zone of the Russian Federation, this task requires a more elaborate approach. Current building techniques, designed for flatlands with relatively comfortable climates, cannot be applied to this territory without degrading the quality of the living environment. Environmental comfort is influenced by many factors, and one of them is the aeration regime. This study is aimed at researching the aeration regime of built-up areas on the sloping lands of the Arctic zone of the Russian Federation and identifying the features of its formation. The object of this study is a residential development on the sloping lands of the Arctic zone of the Russian Federation. The subject of the study is the external aeration regime at the level of 1.2 m from the ground level of the residential development on the sloping lands of the Arctic zone of the Russian Federation. These parameters were explored, and the aeration regime was assessed using such advanced software packages as QG for the GIS analysis of the area and ANSYS Fluent for the mathematical modeling of the aeration regime. The results of the research are presented in the form of graphs, dependency tables, and petal diagrams visually demonstrating the distribution of discomfortable zones for different morphotypes of development on various slopes most widely spread in the Arctic zone of the Russian Federation. The theoretical research was pilot-tested in the existing residential development area in Murmansk. The results of the study are usable in practice if respective land use documents are drafted for residential areas of settlements in the Arctic zone of the Russian Federation

Features of Assessment and Formation of the Aeration Regime of Residential Development on the Sloping Lands of the Russian Arctic

The urban development of areas in the Arctic zone of the Russian Federation is a relevant and important task to be tackled by contemporary urban planners. This focus is largely explained by the development of the Northern Sea Route (NSR) and its port cities. Last but not least, to develop these cities means to ensure a comfortable living environment for local residents and visiting specialists. However, given the harsh climate in the Arctic zone of the Russian Federation, this task requires a more elaborate approach. Current building techniques, designed for flatlands with relatively comfortable climates, cannot be applied to this territory without degrading the quality of the living environment. Environmental comfort is influenced by many factors, and one of them is the aeration regime. This study is aimed at researching the aeration regime of built-up areas on the sloping lands of the Arctic zone of the Russian Federation and identifying the features of its formation. The object of this study is a residential development on the sloping lands of the Arctic zone of the Russian Federation. The subject of the study is the external aeration regime at the level of 1.2 m from the ground level of the residential development on the sloping lands of the Arctic zone of the Russian Federation. These parameters were explored, and the aeration regime was assessed using such advanced software packages as QG for the GIS analysis of the area and ANSYS Fluent for the mathematical modeling of the aeration regime. The results of the research are presented in the form of graphs, dependency tables, and petal diagrams visually demonstrating the distribution of discomfortable zones for different morphotypes of development on various slopes most widely spread in the Arctic zone of the Russian Federation. The theoretical research was pilot-tested in the existing residential development area in Murmansk. The results of the study are usable in practice if respective land use documents are drafted for residential areas of settlements in the Arctic zone of the Russian Federation