13 research outputs found

    Model structure for the natural history of human papillomavirus infection and cervical cancer.

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    <p>The model structure reflects the natural history of HPV infection towards cervical cancer. Women can be infected by HPV and progress to low-grade CIN or high-grade CIN, or regress with natural immunity. Low-grade CIN progress to high-grade CIN, or regress thanks to the natural immunity. High-grade CIN progress to invasive cervical cancer (local, regional and distant cancer), or regress thanks to the natural immunity. In the male model, there are three compartments considered: susceptibility to infection, infection and recovery with natural immunity. Female can be protected by HPV vaccine.</p

    Study sites in Attapeu province, the Lao PDR.

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    <p>Don Ngew and Hard Sun villages are located in Xaysetha district (API = 31.2); Vong Say and Ta Oum villages are located in Phouvong district (API = 103.4); and Hard Sai Soung and Som Poi villages are located in Sanamxay district (API = 59.9). API, annual parasite incidence (according to the API data from 2013). Map of Laos (left), Data source: CIESIN, CIAT, GPW, Available from: <a href="http://sedac.ciesin.columbia.edu/gpw" target="_blank">http://sedac.ciesin.columbia.edu/gpw</a>. Map of Attapeu province (right) was created by the authors.</p