Forest plot showing differences in the rate of venous thromboembolism after total knee arthroplasty between patients with rheumatoid arthritis (RA) and osteoarthritis (OA).

<p>Forest plot showing differences in the rate of venous thromboembolism after total knee arthroplasty between patients with rheumatoid arthritis (RA) and osteoarthritis (OA).</p

Meta-regression analysis comparing associations of age and gender with rates of deep vein thrombosis (DVT) and venous thromboembolism (VTE) after total knee arthroplasty in patients with rheumatoid arthritis and osteoarthritis.

<p>Meta-regression analysis comparing associations of age and gender with rates of deep vein thrombosis (DVT) and venous thromboembolism (VTE) after total knee arthroplasty in patients with rheumatoid arthritis and osteoarthritis.</p

Incidence of Deep Vein Thrombosis and Venous Thromboembolism following TKA in Rheumatoid Arthritis versus Osteoarthritis: A Meta-Analysis

<div><p>This meta-analysis was designed to compare the incidence of deep vein thrombosis (DVT) and venous thromboembolism (VTE) following total knee arthroplasty (TKA) in patients with rheumatoid arthritis (RA) and osteoarthritis (OA). All studies directly comparing the post-TKA incidence of DVT and/or VTE in patients with RA and OA were included. For all comparisons, odds ratios and 95% confidence intervals (CI) were calculated for binary outcomes. Six studies were included in the meta-analysis. The pooled data showed that the combined rates of asymptomatic and symptomatic DVT did not differ significantly in the RA and OA groups (1065/222,714 [0.5%] vs. 35,983/6,959,157 [0.5%]; OR 0.77, 95% CI: 0.57 to 1.02; P = 0.07). The combined rates of asymptomatic and symptomatic DVT and pulmonary embolism (PE) after TKA were significantly lower in the RA than in the OA group (1831/225,406 [0.8%] vs. 63,953/7,018,721 [0.9%]; OR 0.76, 95% CI: 0.62 to 0.93; P = 0.008). Conclusiviely, the DVT rates after primary TKA were similar in RA and OA patients. In contrast, the incidence of VTE (DVT plus PE) after primary TKA was lower in RA than in OA patients, despite patients with RA being at theoretically higher risk of thrombi due to chronic inflammation.</p></div

PRISMA (Preferred Reporting Items for Systematic reviews and Meta-analyses) flow diagram of the identification and selection of the studies included in this meta-analysis.

<p>PRISMA (Preferred Reporting Items for Systematic reviews and Meta-analyses) flow diagram of the identification and selection of the studies included in this meta-analysis.</p

Demographic data, opening gap, and preoperative and postoperative alignment in knees with rotation greater than 3° and less than 3°.

Demographic data, opening gap, and preoperative and postoperative alignment in knees with rotation greater than 3° and less than 3°.</p

Forest plot showing differences in the rate of deep vein thrombosis after total knee arthroplasty between patients with rheumatoid arthritis (RA) and osteoarthritis (OA).

<p>Forest plot showing differences in the rate of deep vein thrombosis after total knee arthroplasty between patients with rheumatoid arthritis (RA) and osteoarthritis (OA).</p

Receiver operating characteristics analysis.

Receiver operating characteristic curves illustrating the optimal cut-off values for opening gap width predicting > 3° distal tibial external rotation.</p

Characteristics of the studies included in the meta-analysis.

<p>Characteristics of the studies included in the meta-analysis.</p

Measurement of the angle of vertical osteotomy direction and biplane osteotomy angle on computed tomography.

(A) Line 1, a tangent line to posterior tibia plateau is drawn on the axial image of tibia plateau level. (B) Line 1’, copied and pasted from Fig 1A. The angle of vertical osteotomy direction is determined between line 1’ and vertical osteotomy (line 2). (C) A sagittal image at the prominent tibial tuberosity level. The biplane osteotomy angle is determined between vertical osteotomy (line 3) and oblique osteotomy (line 4).</p

Measuring the angle of the axial rotational change of the distal tibia after HTO.

Two lines were drawn from the sulcus of the posterior border of the tibial plateau to the marked preoperative and postoperative tibial tuberosity positions overlaid on the tibial plateaus of the preoperative and postoperative three-dimensional model on the axial planes.</p