PtRuFe/Carbon Nanotube Composites as Bifunctional Catalysts for Efficient Methanol Oxidation and Oxygen Reduction

The design of bifunctional catalysts with high performance and low platinum for the oxygen reduction reaction (ORR) and the methanol oxidation reaction (MOR) is of significant implication to promote the industrialization of fuel cells. In our work, Pt/carbon nanotube (CNT), Pt3Ru/CNT, and PtRu/CNT catalysts were synthesized by plasma heat treatment, in which the pyrolysis reduction of organometallic salts and the dispersion of CNTs were achieved simultaneously, and catalytic nanoparticles with uniform particle size were anchored on the dispersed CNT surface. Later, Fe was further introduced, and PtFe/CNT, Pt3RuFe/CNT, and PtRuFe/CNT catalysts were synthesized by calcination, and the structure and electrochemical properties in both MOR and ORR of all as-synthesized catalysts were investigated. The results indicated that plasma thermal treatment has the advantage of rapidness and immediacy in the synthesis of catalysts, and the Pt/CNT, Pt3Ru/CNT, and PtRu/CNT catalysts exhibited better electrocatalytic properties than commercial platinum (JM-Pt/C) catalysts. Meanwhile, the introduction of Fe during the calcination further changed the surface electronic properties of catalytic nanoparticles and enhanced the graphitization degree of catalysts; the PtRuFe/CNT catalyst exhibited outstanding electrocatalytic properties with a mass activity of 834.3 mA mg–1 for MOR and a half-wave potential of 0.928 V in alkaline media for ORR. The combination of plasma thermal treatment and calcination puts forward a novel strategy for the optimization of catalysts, and the synthesis method based on plasma dispersion needs to be further optimized to achieve its large-scale promotion

Biomolecular-Induced Synthesis of Self-Assembled Hierarchical La(OH)CO₃ One-Dimensional Nanostructures and Its Morphology-Held Conversion toward La₂O₃ and La(OH)₃

Novel hierarchical layer-by-layer self-assembled one-dimensional (1D) La(OH)CO3 nanostructures, with a diameter of around 700 nm and lengths in the range of 6−8 μm, were synthesized by a developed hydrothermal method using La2O3 and glycine as the starting materials. Various experimental conditions, such as the reaction time, temperature, and the molar ratios of the starting reagents, were studied. The obtained 1D La(OH)CO3 nanostructures can be successfully converted to La2O3 and La(OH)3 nanorods via calcination under appropriate conditions. Analytical methods such as X-ray diffraction, scanning electron microscopy, transmission electron microscopy, and selected area electron microscopy were employed to characterize these products, and the possible growth mechanism of 1D La(OH)CO3 nanostructures was explored. The UV−visible diffuse reflectance absorbance spectra indicate that the 1D nanostructures have enhanced UV-light absorbance properties in contrast to the bulk materials. The electrochemical studies show that 1D La(OH)CO3 nanostructures have a stronger ability to promote electron transfer between ascorbic acid (H2A) and the glass−carbon (GC) electrode than the bulk La(OH)CO3. These layer-by-layer self-assembled hierarchical products have possible application as an efficient support matrix for the immobilization of enzymes and some biomolecules. This one-pot method is likely to be useful in the preparation of many other layered structures

Presentation_1_Mortality and Clinical Predictors After Percutaneous Mitral Valve Repair for Secondary Mitral Regurgitation: A Systematic Review and Meta-Regression Analysis.pdf

BackgroundPercutaneous mitral valve repair (PMVR) provides an available choice for patients suffering from secondary mitral regurgitation (SMR), especially those whose symptoms persist after optimal, conventional, heart-failure therapy. However, conflicting results from clinical trials have created a problem in identifying patients who will benefit the most from PMVR.ObjectiveTo pool mortality data and assess clinical predictors after PMVR among patients with SMR. To this end, subgroup and meta-regression analyses were additionally performed.MethodsWe searched PubMed, EMBASE, and Cochrane databases, and 13 studies were finally included for meta-analysis. Estimated mortality and 95% confidence intervals (CIs) were obtained using a random-effects proportional meta-analysis. We also carried out a meta-regression analysis to clarify the potential influence of important covariates on mortality.ResultsA total of 1,259 patients with SMR who had undergone PMVR were enrolled in our meta-analysis. The long-term estimated pooled mortality of PMVR was 19.3% (95% CI: 13.6–25.1). Meta-regression analysis showed that mortality was directly proportional to cardiac resynchronization therapy (CRT) (β = 0.009; 95% CI: 0.002–0.016; p = 0.009), an effective regurgitant orifice (ERO) (β = 0.009; 95% CI: 0.000–0.018; p = 0.047), and a mineralocorticoid receptor antagonist (MRA) use (β = −0.015; 95% CI: −0.023–−0.006; p Conclusion and RelevanceThe pooled mortality of PMVR was 19.3% (95% CI: 13.6–25.1). Further meta-regression indicated that AF was associated with a better outcome in conjunction with the use of a mitral annuloplasty device, while better LV functioning predicted a better outcome after the implantation of an edge-to-edge repair device.</p

Electroless Deposition of Platinum Nanoparticles in Room-Temperature Ionic Liquids

The electroless deposition of Pt nanoparticles (Pt-NPs) could be carried out by dissolving potassium tetrachloroplatinate­(II) (K₂[PtCl₄]) in 1-ethyl-3-methylimidazolium (EMI⁺) room-temperature ionic liquids (RTILs) containing bis­(trifluoromethylsulfonyl) imide (NTf₂^–) or tetrafluoroborate (BF₄^–) anion and small cations, such as H⁺, K⁺, and Li⁺. In this case, no deposition of Pt-NPs occurred in RTILs without such small cations. The formation of Pt-NPs was only observed in RTILs containing trifluoromethanesulfonimide (HNTf₂) and protons at high temperature (≥80 °C) when potassium hexachloroplatinate­(IV) (K₂[PtCl₆]) was dissolved in the RTILs. The obtained Pt-NPs gave a characteristic absorption spectrum of ultrasmall Pt-NPs. The ultrasmall and uniform Pt-NPs of ca. 1–4 nm in diameter were produced and the Pt-NPs/EMI⁺NTf₂^– dispersion was kept stably for several months without adding any additional stabilizers or capping molecules. The identified Fourier-transform patterns along the [0 1 1] zone axis were observed for the TEM images of Pt-NPs. On the basis of the results obtained, a probable mechanism of the electroless formation of Pt-NPs is discussed

Image_1_Construction of novel hypoxia-related gene model for prognosis and tumor microenvironment in endometrial carcinoma.tif

IntroductionEndometrial cancer is currently one of the three most common female reproductive cancers, which seriously threatens women’s lives and health. Hypoxia disrupts the tumor microenvironment, thereby affecting tumor progression and drug resistance.MethodsWe established hypoxia-related gene model to predict patient prognosis and 1-, 3-, and 5-year overall survival rates. Then, the expression level of hypoxia-related genes and survival data were extracted for comprehensive analysis by Cox regression analysis, and the model was established.ResultsWe analyzed the survival and prognosis of patients in the high and low-risk groups. The Kaplan-Meier curve showed that the low-risk group is associated with a better survival rate. The 1-, 3-, and 5-year AUC values of the model were 0.680, 0.698, and 0.687, respectively. Finally, we found that LAG3 may be a potential immune checkpoint for endometrial cancer.ConclusionWe found four hypoxia-related genes (ANXA2, AKAP12, NR3C1, and GPI) associated with prognosis. The hypoxia-related gene model can also predict prognosis and tumor microenvironment in endometrial cancer.</p

Image_2_Construction of novel hypoxia-related gene model for prognosis and tumor microenvironment in endometrial carcinoma.tif

IntroductionEndometrial cancer is currently one of the three most common female reproductive cancers, which seriously threatens women’s lives and health. Hypoxia disrupts the tumor microenvironment, thereby affecting tumor progression and drug resistance.MethodsWe established hypoxia-related gene model to predict patient prognosis and 1-, 3-, and 5-year overall survival rates. Then, the expression level of hypoxia-related genes and survival data were extracted for comprehensive analysis by Cox regression analysis, and the model was established.ResultsWe analyzed the survival and prognosis of patients in the high and low-risk groups. The Kaplan-Meier curve showed that the low-risk group is associated with a better survival rate. The 1-, 3-, and 5-year AUC values of the model were 0.680, 0.698, and 0.687, respectively. Finally, we found that LAG3 may be a potential immune checkpoint for endometrial cancer.ConclusionWe found four hypoxia-related genes (ANXA2, AKAP12, NR3C1, and GPI) associated with prognosis. The hypoxia-related gene model can also predict prognosis and tumor microenvironment in endometrial cancer.</p

Electrochemical In Situ Na Doping to Construct High-Performance Lithium-Rich Cathode

Lithium-rich layered oxides are regarded as the next generation of cathode materials for lithium ion batteries. However, the irreversible release of oxygen during cycling can lead to serious failure problems. In order to solve the above problems, this paper proposes an electrochemical in situ Na doping method with ultrahigh content, homogenization, and no residual alkali. The traditional solid-phase sintering method has low doping content (<10%), no obvious expansion of layer spacing, more residual alkali and multiphase interface, which will lead to serious structural and interface failure problems during charging and discharging. The ultrahigh Na content (30%) leads to the extra-large layer spacing (0.547 nm), and the integration of nonbonded O 2p orbitals is effectively inhibited by coulomb repulsion, which greatly improves the electrochemical performance of cathode materials. The mechanism of electrochemical doping was investigated by a series of in-situ/ex-situ characterizations and density functional theory. This study provides a new way to improve the performance of Li-rich cathode materials

Table_2_Construction of novel hypoxia-related gene model for prognosis and tumor microenvironment in endometrial carcinoma.docx

IntroductionEndometrial cancer is currently one of the three most common female reproductive cancers, which seriously threatens women’s lives and health. Hypoxia disrupts the tumor microenvironment, thereby affecting tumor progression and drug resistance.MethodsWe established hypoxia-related gene model to predict patient prognosis and 1-, 3-, and 5-year overall survival rates. Then, the expression level of hypoxia-related genes and survival data were extracted for comprehensive analysis by Cox regression analysis, and the model was established.ResultsWe analyzed the survival and prognosis of patients in the high and low-risk groups. The Kaplan-Meier curve showed that the low-risk group is associated with a better survival rate. The 1-, 3-, and 5-year AUC values of the model were 0.680, 0.698, and 0.687, respectively. Finally, we found that LAG3 may be a potential immune checkpoint for endometrial cancer.ConclusionWe found four hypoxia-related genes (ANXA2, AKAP12, NR3C1, and GPI) associated with prognosis. The hypoxia-related gene model can also predict prognosis and tumor microenvironment in endometrial cancer.</p

Image_3_Construction of novel hypoxia-related gene model for prognosis and tumor microenvironment in endometrial carcinoma.tif

IntroductionEndometrial cancer is currently one of the three most common female reproductive cancers, which seriously threatens women’s lives and health. Hypoxia disrupts the tumor microenvironment, thereby affecting tumor progression and drug resistance.MethodsWe established hypoxia-related gene model to predict patient prognosis and 1-, 3-, and 5-year overall survival rates. Then, the expression level of hypoxia-related genes and survival data were extracted for comprehensive analysis by Cox regression analysis, and the model was established.ResultsWe analyzed the survival and prognosis of patients in the high and low-risk groups. The Kaplan-Meier curve showed that the low-risk group is associated with a better survival rate. The 1-, 3-, and 5-year AUC values of the model were 0.680, 0.698, and 0.687, respectively. Finally, we found that LAG3 may be a potential immune checkpoint for endometrial cancer.ConclusionWe found four hypoxia-related genes (ANXA2, AKAP12, NR3C1, and GPI) associated with prognosis. The hypoxia-related gene model can also predict prognosis and tumor microenvironment in endometrial cancer.</p

Multifunctional Ho₂O₃ Coating with Oxygen Vacancies Enables High-Performance Lithium-Rich Layered Oxide Cathodes

Li-rich materials with exceptionally high specific capacity have great potential for the commercialization of cathode materials in the future. However, irreversible oxygen loss, transition metal (TM) dissolution, and structural degradation during cycling make the commercialization of Li-rich cathode materials difficult. Here, a uniform Ho2O3 coating was formed on the surface of Li-rich layered oxide (LLO) cathodes due to the good electrical conductivity and abundant oxygen vacancies of Ho2O3. The high conductivity of the material improves the kinetic performance. The modification layer effectively stabilizes the evolution of CEI during the long cycling process and inhibits the occurrence of irreversible side reactions. More importantly, the abundant oxygen vacancies effectively inhibited oxygen precipitation and enhanced the reversibility of anion redox. The charging and discharging processes of the material and the modification mechanism are deeply analyzed through a series of characterizations. The results show that the modification method effectively improves the electrochemical performance of the materials. The capacity loss of the Ho2O3-coated material is less than that of LLO after long cycling at 1C and 0.5C, and the discharge-specific capacity of the modified material can be increased to 158.1 mAh g–1 at 5C. This paper provides a new guiding path for the design of future high-voltage LLO materials