3D Printing Technology Acceptance through a Peer-Assisted Learning Continuing Education Course

As rehabilitation technologies rapidly develop, the lack of evidence-based training remains a barrier to technology adoption. Continuing education (CE) may provide training opportunities for new technologies, specifically 3D printing. Current models of CE course design rely on traditional, pedagogical methods, including didactic delivery, as opposed to applying adult learning models, which integrate experiential, self-directed learning to promote collaboration and problem-solving. This study sought to determine whether the active learning approach of peer-assisted learning (PAL) promoted collaboration and transference of knowledge between rehabilitation clinician peers when learning 3D printing. In this mixed methods study, 35 clinicians from occupational therapy, physical therapy, and speech language pathology disciplines participated in two hours of CE, which integrated tenets of PAL to explore attitudes toward technology adoption perceptions as measured by the Technology Acceptance Model (TAM). Pretest and posttest results were analyzed using paired permutation tests. All TAM responses improved significantly (p \u3c .05), suggesting that for rehabilitation clinicians, CE using an andragogical PAL approach contributed to improving technology acceptance of 3D printing. Content analysis of posttest open-ended questions further explored PAL implementation. The qualitative themes were: (1) Active opportunities supported learning, (2) group format facilitated problem-solving within a team, (3) technology was easier than expected, and (4) barriers remain for technology application in practice. In conclusion, the themes support the integration of PAL as a delivery method of CE to enhance technology adoption

Predictors of Comorbid Eating Disorders and Association with Other Obsessive-Compulsive Spectrum Disorders in Trichotillomania

Trichotillomania (TTM) and eating disorders (ED) share many phenomenological similarities, including ritualized compulsive behaviors. Given this, and that comorbid EDs may represent additional functional burden to hair pullers, we sought to identify factors that predict diagnosis of an ED in a TTM population. Subjects included 555 adult females (age range 18–65) with DSM-IV-TR TTM or chronic hair pullers recruited from multiple sites. 7.2% (N = 40) of our TTM subjects met criteria for an ED in their lifetime. In univariable regression analysis, obsessive-compulsive disorder (OCD), Yale-Brown Obsessive Compulsive Scale (Y-BOCS) worst-ever compulsion and total scores, certain obsessive-compulsive spectrum disorders, anxiety disorder, attention-deficit/hyperactivity disorder (ADHD), and substance disorder all met the pre-specified criteria for inclusion in the multivariable analysis. In the final multivariable model, diagnosis of OCD (OR: 5.68, 95% CI: 2.2–15.0) and diagnosis of an additional body-focused repetitive behavior disorder (BFRB) (OR: 2.69, 95% CI: 1.1–6.8) were both associated with increased risk of ED in TTM. Overall, our results provide further support of the relatedness between ED and TTM. This finding highlights the importance of assessing for comorbid OCD and additional BFRBs in those with TTM. Future research is needed to identify additional predictors of comorbid disorders and to better understand the complex relationships between BFRBs, OCD and EDs

The Grizzly, September 23, 2004

Get Down in the Lounge • USGA Amendments Cause Controversy • Wismer Rumors Exposed • Family Day is Just Around the Corner • You got SERVed! • Medulla: Soul for Your Brain • Lead the Way: UC Leadership Studies Program • Care to Dance? • Opinions: Should More Public Places Move Towards a Complete No-smoking Policy?; Tattoo or not to Tattoo? • My Summer Vacation Camping at Death Pond • The Kobe Bryant Sagahttps://digitalcommons.ursinus.edu/grizzlynews/1565/thumbnail.jp

The Grizzly, September 16, 2004

Ursinus Goes Wireless • New Bookstore, New Look, Same Sentiments • Project Pericles Seeks to Remedy Political Apathy • Election 101: Who do you Side With? • Environmental Studies Professor gets with the Program • Ursinus Student Awarded $40,000 Grant • Are Ursinus Students Apathetic? • Ursinus Professors Dance the Night Away in Russia • Opinions: Should the Miss America Pageant Qualify as one of the Great American pastimes?; Why America Needs Four More Years of George W. Bush; Surviving \u27R-ships\u27 in College • Field Hockey Team Continues Where They Left Off • Men\u27s Soccer Shows Promisehttps://digitalcommons.ursinus.edu/grizzlynews/1564/thumbnail.jp

The Grizzly, October 26, 2006

Editorial: Putting the Pieces Back Together • Possible Scam Raises Concerns • Town Hall Meeting Brings Forth Campus Issues • Food Drive a Success • Fall is in the Air • Story Behind the Statue: Praha • Get to Know the Nominees • Opinions: Long Live Noise; Swept Under the Rug; Truth About Study Abroad • Women\u27s Volleyball Swept by Gettysburg • Bullets Offense Too Much for Bears • Bears Make Run for Playoffshttps://digitalcommons.ursinus.edu/grizzlynews/1722/thumbnail.jp

Heated Tobacco Product Iqos Induces Unique Metabolic Signatures in Human Bronchial Epithelial Cells

Metabolic signatures are lacking for heated tobacco products, making it crucial to identify new biosignatures of lung damage. This will enable the establishment of product-specific guidelines and an understanding of associated toxicity

The Grizzly, September 28, 2006

Anti-Racist Writer and Educator Speaks to Ursinus Community • Spinach Recall and Dining at Ursinus • Smoking Ban Introduced • Images from Annual Fringe Festival • USGA Town Hall Meeting • Shades of Clay Closes • Beyond the Condom: Guide to Safe Sex • Constitution Day: A Review • An Afternoon with Johnny Knoxville and Bam Margera • Watson Fellowship • Opinions: The Core ; New Zack City • Soccer Struggles • Letter to the Editor • NCAA Drug Testinghttps://digitalcommons.ursinus.edu/grizzlynews/1719/thumbnail.jp

The Lantern Vol. 74, No. 1, Fall 2006

• Seven Haikus About Insomnia • Lunch Hour • Divorced Parents and Flower Guts • 24 • Lily • Growth • Narcissistically Admiring You • Mysterious Avocado • Aloha Roast • Summer • Lines • Internalizing • San Francisco • Numb Candle • Moments No. 1 • Tanka • Euphemism • We be Malllllll • Dragon Magic • Time for the Magic Show • Green • Job • The Shire • Venom • The Seasons of Love • The Position • Fragments of an Artist • Peace • Vagabond Nights • Rerum Concordia Discorshttps://digitalcommons.ursinus.edu/lantern/1169/thumbnail.jp

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

Long noncoding RNAs (lncRNAs) are commonly dys-regulated in tumors, but only a handful are known toplay pathophysiological roles in cancer. We inferredlncRNAs that dysregulate cancer pathways, onco-genes, and tumor suppressors (cancer genes) bymodeling their effects on the activity of transcriptionfactors, RNA-binding proteins, and microRNAs in5,185 TCGA tumors and 1,019 ENCODE assays.Our predictions included hundreds of candidateonco- and tumor-suppressor lncRNAs (cancerlncRNAs) whose somatic alterations account for thedysregulation of dozens of cancer genes and path-ways in each of 14 tumor contexts. To demonstrateproof of concept, we showed that perturbations tar-geting OIP5-AS1 (an inferred tumor suppressor) andTUG1 and WT1-AS (inferred onco-lncRNAs) dysre-gulated cancer genes and altered proliferation ofbreast and gynecologic cancer cells. Our analysis in-dicates that, although most lncRNAs are dysregu-lated in a tumor-specific manner, some, includingOIP5-AS1, TUG1, NEAT1, MEG3, and TSIX, synergis-tically dysregulate cancer pathways in multiple tumorcontexts

Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

Although theMYConcogene has been implicated incancer, a systematic assessment of alterations ofMYC, related transcription factors, and co-regulatoryproteins, forming the proximal MYC network (PMN),across human cancers is lacking. Using computa-tional approaches, we define genomic and proteo-mic features associated with MYC and the PMNacross the 33 cancers of The Cancer Genome Atlas.Pan-cancer, 28% of all samples had at least one ofthe MYC paralogs amplified. In contrast, the MYCantagonists MGA and MNT were the most frequentlymutated or deleted members, proposing a roleas tumor suppressors.MYCalterations were mutu-ally exclusive withPIK3CA,PTEN,APC,orBRAFalterations, suggesting that MYC is a distinct onco-genic driver. Expression analysis revealed MYC-associated pathways in tumor subtypes, such asimmune response and growth factor signaling; chro-matin, translation, and DNA replication/repair wereconserved pan-cancer. This analysis reveals insightsinto MYC biology and is a reference for biomarkersand therapeutics for cancers with alterations ofMYC or the PMN